706 research outputs found
Medicina d'Emergenza-Urgenza e antibiotico-terapia L'importanza delle linee guida locali
Lâintroduzione degli antibiotici ha drasticamente ridotto la mortalitĂ per malattie come polmonite, endocardite e meningite, rivoluzionando la pratica medica, la quale Ăš stata trasformata da diagnostica e non interventistica in terapeutica ed interventistica.
Lo sviluppo di resistenza agli antimicrobici Ăš riconosciuto come una delle piĂč grandi minacce alla salute del genere umano, tanto che lâorganizzazione mondiale della sanitĂ (WHO) ha proclamato lâantimicrobico-resistenza il focus della giornata mondiale della salute nel 2011.
In assenza di antibiotici efficaci, diversi campi della medicina saranno gravemente ostacolati, inclusi la chirurgia, la cura dei neonati prematuri, la chemioterapia oncologica, la terapia intensiva e la medicina dei trapianti.
Eâ stato coniato lâacronimo ESKAPE (Enterococcus, Staphilococcus, Klebsiella, Acinetobacter, Pseudomonas ed ESBL â E.coli ed Enetrobacter) per indicare i piĂč rilevanti organismi multi resistenti.
Le malattie causate dai patogeni ESKAPE, Mycobacterium tuberculosis multi resistente e altri altamente problematici batteri antibiotico resistenti, come il Clostridium difficile ipervirulento e resistente ai fluorochinolonici, lo Streptococcus pneumoniae multiresistente e Neisseria gonorrhoeae, sono associate ad elevata morbiditĂ , mortalitĂ ed elevati costi sanitari ovunque nel mondo.
La politica per il corretto impiego degli antibiotici Ăš lâelemento chiave per evitare lâabuso e lâuso incorretto degli antibiotici. Gli obiettivi principali sono raggiungere il miglior outcome clinico correlato allâuso degli antibiotici, ridurre la tossicitĂ e gli altri eventi avversi, ridurre i costi per la cura delle infezioni e limitare la selezione di ceppi resistenti agli antimicrobic
Social media and politics: the case of Ukraine
Abstract
Nowadays, politics is undergoing several changes, especially because of the growing use of social media from politicians, who are using these virtual platforms as tools to gain more and more consent. Social media are also leading to extreme democratization of politics, making it possible for non-politicians not only to enter the sphere of politics but even to win major competitions, such as presidential elections. To bring an actual and highly illustrative example, in this article the authors go through a deep analysis of the former actor and recently elected prime minister of Ukraine Volodimir Zelenskij and his strategical use of social media compared to the one carried out by his opponents, leading him to win the presidential elections with an enormous consent
Ukraine a country in crisis between Europe, Russia, and a complex electoral process
Abstract
To this day, Ukraine is still experiencing difficult times both economically and politically. The economic and political crisis at the end of 2014, which led to the dismissal of President Yanukovich, meant that the territory of Crimea and, therefore, the port of Sevastopol as well, remained under Russian control. The new elections of 2019 carried a breath of fresh air and hope also for new relationships with Russia. The paper wants to photograph this situation and analyse the recent 2019 presidential elections
Skin Safety and Health Prevention: an Overview of Chemicals in Cosmetic Products
Introduction. Cosmetic products contain a wide range of chemicals to which we are exposed every day. The aim of the study was to determine the presence of potential dangerous substances which can cause adverse health effects by examining product labels.Methods. A total of 283 products were collected from various shops in Lecce (Italy) and divided into 3 categories: rinse-off, leave-on and make-up. The label of every product was examined and a list including fragrances, preservatives and other chemicals of concern was created.Results. Fragrances were present in 52.3% of the examined products, mostly limonene (76.9%) and linalool (64.6%) but also citronellol (34.1%), geraniol (31.5%), coumarin (30%) and hexyl cinnamal (29.2%). Preservatives showed a rate of 60% and the most frequently identified were phenoxyethanol (48.7%), sodium benzoate (35.6%), potassium sorbate (22%), methylparaben (15.2%) and MI/MCI (9.9%). The other chemicals of concern were detected in 58% of products; included PEGs (62.3%), acrylate copolymer (34%), petrolatum (17.2%), polysorbates (14,8%), BHT (14.7%), ethylhextyl methoxycinnamate (13.6%), benzophenone-1 (3.7%), benzophenone-3 (4.9%), BHA (1.6%), cocamide DEA and toluene (1.2%).Conclusions. The use of many of these substances is allowed within certain limits, due to their toxicity at higher concentrations. Other important aspects should be considered as, for instance, the possibility of long-term effects. On the other hand, other substances may induce several acute adverse side-effects, i.e. contact dermatitis and allergic reactions. For these reasons, an enhancement of the criteria used for cosmetics formulation is required since many chemicals used singularly or combined are potentially unsafe
Characterization of monovarietal olive oils obtained from mills of Calabria region (Southern Italy)
AbstractThe qualitative characteristics of four monovarietal olive oils produced in Calabria region (Southern Italy) were evaluated. The aim of this work was to evidence the differences on chemical parameters due to variety and to growing environment. Results demonstrated a large variability in qualitative indexes according to the variety. Most of the Grossa di Gerace oils sampled in Ionian Southern coast revealed a high total acidity (percentage upper 0.8% of oleic acid). Fatty acid composition showed some varietal characters: in Grossa di Gerace oils possessed a low content of oleic acid and many Carolea oils showed a heptadecenoic acid level higher than 0.3% as European Rules requires for the extra virgin olive oil category. Carolea cultivar is widely grown in different sites of Calabria and so it is influenced by the different climatic conditions: the obtained oils strongly differed according to the production area
Chlorambucil plus rituximab with or without maintenance rituximab as first-line treatment for elderly chronic lymphocytic leukemia patients
Les droits disciplinaires des fonctions publiques : « unification », « harmonisation » ou « distanciation ». A propos de la loi du 26 avril 2016 relative à la déontologie et aux droits et obligations des fonctionnaires
The production of tt⟠, W+bb⟠and W+cc⟠is studied in the forward region of protonâproton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98±0.02 fbâ1 . The W bosons are reconstructed in the decays WââÎœ , where â denotes muon or electron, while the b and c quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions.The production of , and is studied in the forward region of proton-proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98 0.02 \mbox{fb}^{-1}. The bosons are reconstructed in the decays , where denotes muon or electron, while the and quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions
Multidifferential study of identified charged hadron distributions in -tagged jets in proton-proton collisions at 13 TeV
Jet fragmentation functions are measured for the first time in proton-proton
collisions for charged pions, kaons, and protons within jets recoiling against
a boson. The charged-hadron distributions are studied longitudinally and
transversely to the jet direction for jets with transverse momentum 20 GeV and in the pseudorapidity range . The
data sample was collected with the LHCb experiment at a center-of-mass energy
of 13 TeV, corresponding to an integrated luminosity of 1.64 fb. Triple
differential distributions as a function of the hadron longitudinal momentum
fraction, hadron transverse momentum, and jet transverse momentum are also
measured for the first time. This helps constrain transverse-momentum-dependent
fragmentation functions. Differences in the shapes and magnitudes of the
measured distributions for the different hadron species provide insights into
the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any
supplementary material and additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb
public pages
Study of the decay
The decay is studied
in proton-proton collisions at a center-of-mass energy of TeV
using data corresponding to an integrated luminosity of 5
collected by the LHCb experiment. In the system, the
state observed at the BaBar and Belle experiments is
resolved into two narrower states, and ,
whose masses and widths are measured to be where the first uncertainties are statistical and the second
systematic. The results are consistent with a previous LHCb measurement using a
prompt sample. Evidence of a new
state is found with a local significance of , whose mass and width
are measured to be and , respectively. In addition, evidence of a new decay mode
is found with a significance of
. The relative branching fraction of with respect to the
decay is measured to be , where the first
uncertainty is statistical, the second systematic and the third originates from
the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb
public pages
Measurement of the ratios of branching fractions and
The ratios of branching fractions
and are measured, assuming isospin symmetry, using a
sample of proton-proton collision data corresponding to 3.0 fb of
integrated luminosity recorded by the LHCb experiment during 2011 and 2012. The
tau lepton is identified in the decay mode
. The measured values are
and
, where the first uncertainty is
statistical and the second is systematic. The correlation between these
measurements is . Results are consistent with the current average
of these quantities and are at a combined 1.9 standard deviations from the
predictions based on lepton flavor universality in the Standard Model.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-039.html (LHCb
public pages
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