Aquilegia, Vol. 40 No. 4, Fall 2016: Newsletter of the Colorado Native Plant Society

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Aquilegia Volume 41 No. 4 Summer 2017

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Aquilegia Volume 40 No. 2 Annual Conference Issue 2016 Annual Conference 2016; Forty Years of Change: Plants, People, Places

The CoNPS Annual Conference is the primary state gathering and annual fund-raiser for the Colorado Native Plant Society, a non-profit organization. Proceeds from the conference support CoNPS’ wide-ranging projects including education, conservation, native plant gardening, and botanical and horticultural publications and activities.https://epublications.regis.edu/aquilegia/1190/thumbnail.jp

Aquilegia Volume 41 No.1 Winter 2017

IN THIS ISSUE:Forty Years of Progress in Pollination Biology Return of the Native: Colorado Natives in Horticulture Climate Change and Columbines The Ute Learning and Ethnobotany Garden The Urban Prairies Project Book Reviewshttps://epublications.regis.edu/aquilegia/1192/thumbnail.jp

Population genetic structure in European lobsters: implications for connectivity, diversity and hatchery stocking

The European lobster Homarus gammarus is a marine crustacean prized for seafood, but populations across its range are threatened by fishery overexploitation. The species’ larval stages are planktonic, suggesting considerable dispersal among populations. The potential threats of overexploitation and erosion of population structure due to hatchery releases or inadvertent introductions make it important to understand the genetic structuring of populations across multiple geographic scales. Here we assess lobster population structure at a fine scale in Cornwall, southwestern UK, where a hatchery-stocking operation introduces cultured individuals into the wild stock, and at a broader European level, in order to compare the spatial scale of hatchery releases with that of population connectivity. Microsatellite genotypes of 24 individuals from each of 13 locations in Cornwall showed no fine-scale population structure across distances of up to ~230 km. Significant differentiation and isolation by distance were detected at a broader scale, using 300 additional individuals comprising a further 15 European samples. Signals of genetic heterogeneity were evident between an Atlantic cluster and samples from Sweden. Connectivity within the Atlantic and Swedish clusters was high, although evidence for isolation by distance and a transitional zone within the eastern North Sea suggested that direct gene exchange between these stocks is limited and fits a stepping-stone model. We conclude that hatchery-reared lobsters should not be released where broodstock are distantly sourced but, using Cornwall as a case study, microsatellites revealed no evidence that the normal release of hatchery stock exceeds the geographic scale of natural connectivity.European Social FundWorshipful Company of FishmongersBBSRCThis research was supported by Lobster Grower 2, a 3 yr project funded by Innovate-UK (TS/ N006097/1) and BBSRC (BB/N013891/1) under an AgriTech Catalyst Industrial Stage Award. We are also greatly appreciative of the studentship funding provided by the European Social Fund and of the grant awarded by the Fishmonger’s Company, UK, both of which made the work possible

Cloud Hosted Real‐time Data Services for the Geosciences (CHORDS)

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/133550/1/gdj336_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/133550/2/gdj336.pd

Aquilegia, Vol. 40 No. 1 - Winter 2015-2016, Newsletter of the Colorado Native Plant Society

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A comparison of quantitative methods for clinical imaging with hyperpolarized (13)C-pyruvate.

Dissolution dynamic nuclear polarization (DNP) enables the metabolism of hyperpolarized (13)C-labelled molecules, such as the conversion of [1-(13)C]pyruvate to [1-(13)C]lactate, to be dynamically and non-invasively imaged in tissue. Imaging of this exchange reaction in animal models has been shown to detect early treatment response and correlate with tumour grade. The first human DNP study has recently been completed, and, for widespread clinical translation, simple and reliable methods are necessary to accurately probe the reaction in patients. However, there is currently no consensus on the most appropriate method to quantify this exchange reaction. In this study, an in vitro system was used to compare several kinetic models, as well as simple model-free methods. Experiments were performed using a clinical hyperpolarizer, a human 3 T MR system, and spectroscopic imaging sequences. The quantitative methods were compared in vivo by using subcutaneous breast tumours in rats to examine the effect of pyruvate inflow. The two-way kinetic model was the most accurate method for characterizing the exchange reaction in vitro, and the incorporation of a Heaviside step inflow profile was best able to describe the in vivo data. The lactate time-to-peak and the lactate-to-pyruvate area under the curve ratio were simple model-free approaches that accurately represented the full reaction, with the time-to-peak method performing indistinguishably from the best kinetic model. Finally, extracting data from a single pixel was a robust and reliable surrogate of the whole region of interest. This work has identified appropriate quantitative methods for future work in the analysis of human hyperpolarized (13)C data.CJD is jointly funded by the National Institute for Health Research (NIHR), Cambridge Biomedical Research Centre and GlaxoSmithKline (GSK). Additional funding for this study was provided by Cancer Research UK (CRUK, C19212/A16628; C19212/A911376), The Wellcome Trust, Cambridge Experimental Cancer Medicine Centre, Cambridge Cancer Centre, the School of Clinical Medicine at the University of Cambridge and the CRUK and Engineering and Physical Sciences Research Council (EPSRC) Cancer Imaging Centre in Cambridge and Manchester.This is the final version of the article. It first appeared from Wiley via http://dx.doi.org/10.1002/nbm.346

Aquilegia, Vol. 38 No. 4 - Fall, 2014, Newsletter of the Colorado Native Plant Society

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Science granting councils in Sub-Saharan Africa: trends and tensions

This article documents recent trends in science funding support in Sub-Saharan Africa (SSA). We analyse these trends at the SSA regional level alongside a summary of four case studies of science funding in four Science Granting Councils (SGCs) in East Africa. Our findings support the literature on science funding in SSA regarding low levels of funding, cross-country engagement, and the need for capacity building. However, we also find there are tensions among funding and policy actors around the perceived ways in which investment in science will benefit society. We argue that the narratives and logics of science funders and their roots in ‘Republic of Science’ vs. ‘Embedded Autonomy’ rationales for SGC activity must be more transparent to enable critical engagement with the ideas being used to justify spending