8,611 research outputs found

    Bounding Selmer groups for the Rankin--Selberg convolution of Coleman families

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    Let ff and gg be two cuspidal modular forms and let F\mathcal{F} be a Coleman family passing through ff, defined over an open affinoid subdomain VV of weight space W\mathcal{W}. Using ideas of Pottharst, under certain hypotheses on ff and gg we construct a coherent sheaf over V×WV \times \mathcal{W} which interpolates the Bloch-Kato Selmer group of the Rankin-Selberg convolution of two modular forms in the critical range (i.e. the range where the pp-adic LL-function LpL_p interpolates critical values of the global LL-function). We show that the support of this sheaf is contained in the vanishing locus of LpL_p.Comment: Final version. To appear in Canadian Jour. Mat

    EMPIRICAL STUDY ON THE INFLUENCE OF PROCUREMENT METHODS ON LAST PLANNER® SYSTEM IMPLEMENTATION

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    Previous studies have examined various factors that influence the implementation of the Last Planner System (LPS) in construction projects. However, there is limited documented evidence on the influence of procurement methods on the implementation of the LPS. The aim of this study, therefore; is to understand the influence of some selected procurement methods on the implementation of the LPS using case study approach. Three in-depth case studies were conducted on building and highways projects in the UK. The projects were managed with the LPS principles with dissimilar procurement methods. In addition to document analysis and physical observation, 28 in-depth-interviews were conducted. The investigation shows that the prevailing traditional mindset exhibited by the designers in the traditional design bid build (DBB) influences the quality of promises and commitments that could be made during the lookahead planning. From the study, it seems no single procurement method is a sure way to the full application of the LPS process on a project. The study observes that irrespective of the procurement route used, a mindset change towards collaboration among the different stakeholders on the project is fundamental to successful LPS implementation. For instance, on projects where DBB was used and the subcontractors were in framework agreement, the LPS implementation worked well among the subcontractors. The study recommends that the procurement approach to be used on LPS projects should not be too firm, but lithe enough to integrate collaborative working among the different stakeholders on the project for a smooth workflow

    Experimental validation of clock synchronization algorithms

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    The objective of this work is to validate mathematically derived clock synchronization theories and their associated algorithms through experiment. Two theories are considered, the Interactive Convergence Clock Synchronization Algorithm and the Midpoint Algorithm. Special clock circuitry was designed and built so that several operating conditions and failure modes (including malicious failures) could be tested. Both theories are shown to predict conservative upper bounds (i.e., measured values of clock skew were always less than the theory prediction). Insight gained during experimentation led to alternative derivations of the theories. These new theories accurately predict the behavior of the clock system. It is found that a 100 percent penalty is paid to tolerate worst-case failures. It is also shown that under optimal conditions (with minimum error and no failures) the clock skew can be as much as three clock ticks. Clock skew grows to six clock ticks when failures are present. Finally, it is concluded that one cannot rely solely on test procedures or theoretical analysis to predict worst-case conditions

    Agglomeration Elasticities in New Zealand

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    This paper analyses the relationship between firms’ multi-factor productivity and the effective employment density of the areas where they operate. Quantifying these agglomeration elasticities is of central importance in the evaluation of the wider economic benefits of transport investments. We estimate agglomeration elasticities using the Statistics New Zealand prototype Longitudinal Business Database: a firm-level panel covering the period 1999 to 2006. We estimate that an area with 10 percent higher effective density has firms with productivity that is 0.69 percent higher, once we control for the industry specific production functions and sorting of more productive firms across industries and locations. We present separate estimates of agglomeration elasticities for specific industries and regions, and examine the interaction of agglomeration with capital, labour, and other inputs.Agglomeration, urban density, transport evaluation, productivity

    Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity

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    BackgroundAgeing and type 2 diabetes mellitus (T2DM) are risk factors for skeletal muscle loss. We investigated whether anabolic resistance to feeding might underlie accelerated muscle loss in older people with T2DM and whether dysregulated mTOR signalling was implicated.Subjects8 obese men with T2DM, and 12 age-matched controls were studied (age 68±3 vs. 68±6y; BMI: 30±2 vs. 27±5 kg·m-2).MethodsBody composition was measured by dual-X-ray absorptiometry. Insulin and glucose were clamped at post-absorptive concentrations (13±2 vs. 9±3 mU·l-1; 7.4±1.9 vs. 4.6±0.4 mmol·l-1; T2DM vs. controls). Fractional synthetic rates (FSR) of myofibrillar and sarcoplasmic proteins were measured as the rate of incorporation of [13C] leucine during a primed, constant infusion of [1-13C] α-ketoisocaproic acid, 3 h after 10 or 20g of essential amino acids (EAA) were orally administered. Protein expression of total and phosphorylated mTOR signalling proteins was determined by Western blot analysis.ResultsDespite a significantly lower appendicular lean mass index and a greater fat mass index in T2DM vs. controls, basal myofibrillar and sarcoplasmic and post-prandial myofibrillar FSR were similar. After 20g EAA, stimulation of sarcoplasmic FSR was slightly blunted in T2DM patients. Furthermore, feeding 20g EAA increased phosphorylation of mTOR, p70S6k and 4E-BP1 by 60-100% in controls with no response observed in T2DM.ConclusionsThere was clear dissociation between changes in mTOR signalling versus changes in protein synthesis rates. However, the intact anabolic response of myofibrillar FSR to feeding in both groups suggests anabolic resistance may not explain accelerated muscle loss in T2DM
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