7,465 research outputs found
Design of an integrated shallow water wave experiment
The experimental design and instrumentation for an integrated shallow-water surface gravity wave experiment is discussed. The experiment required the measurement of the water surface elevation, meteorological parameters, and directional spectra at a number of locations on a shallow lake. In addition, to acquire data under a wide range of conditions, an experimental period of three years was required. A system of telephone and radio modem links were installed to enable real-time monitoring of instrument performance at eight separate measurement locations on the lake. This system also enabled logging sessions to be optimized to ensure the maximum possible data return from this extended experimentIEEE Oceanic Engineering Societ
The rodent research animal holding facility as a barrier to environmental contamination
The rodent Research Animal Holding Facility (RAHF), developed by NASA Ames Research Center (ARC) to separately house rodents in a Spacelab, was verified as a barrier to environmental contaminants during a 12-day biocompatibility test. Environmental contaminants considered were solid particulates, microorganisms, ammonia, and typical animal odors. The 12-day test conducted in August 1988 was designed to verify that the rodent RAHF system would adequately support and maintain animal specimens during normal system operations. Additional objectives of this test were to demonstrate that: (1) the system would capture typical particulate debris produced by the animal; (2) microorganisms would be contained; and (3) the passage of animal odors was adequately controlled. In addition, the amount of carbon dioxide exhausted by the RAHF system was to be quantified. Of primary importance during the test was the demonstration that the RAHF would contain particles greater than 150 micrometers. This was verified after analyzing collection plates placed under exhaust air ducts and rodent cages during cage maintenance operations, e.g., waste tray and feeder changeouts. Microbiological testing identified no additional organisms in the test environment that could be traced to the RAHF. Odor containment was demonstrated to be less than barely detectable. Ammonia could not be detected in the exhaust air from the RAHF system. Carbon dioxide levels were verified to be less than 0.35 percent
Paper Session II-B - Life Sciences Shuttle Flights- 15 Years
Fifteen years ago, the first Life Sciences Announcement of Opportunity offered the promises of man-tended microgravity flights. For the experiments involving nonhuman elements, i.e., plants, animals, tissues and cells, the Shuttle Transportation System (STS) flights posed both challenges and rewards. The transition from the 1-G laboratory bench to O-G environment has resulted in new information with each succeeding flight. These rewards are measured both in better understanding in methods and materials to conduct research within the microgravity milieu and interpretation of the data obtained.
The engineering systems developed, operational knowledge gained over the past 15 years, and data base of experimental results being developed, can only enhance, support, and stimulate the scientific community\u27s sights toward NASA\u27s next direction - Space Station Freedom
Understanding the patterns, characteristics and trends in the housing sector labour force-AHURI Final Report No.208
The focus of this study is the national policy problem of the gap between housing supply and demand, as identified and monitored by the National Housing Supply Council. Research to date has not focused upon the spatial distribution of labour supply and demand of the housing sector labour force (HSLF). Also research to date has not distinguished between labour engaged in building new dwellings and labour engaged in undertaking alterations and additions. In addressing this research gap, this Final Report presents the summative output of the AHURI research project entitled: Understanding the patterns, characteristics and trends in the housing sector labour force in Australia. It follows the publication of the Positioning Paper for the project (Dalton et al. 2011a).This chapter has presented a response to the secondary research question: What are the temporal dimensions of the HSLF as a whole and the new build and alterations and additions sub-sectors? It first described the categories, containing records of workers who worked in the housing industry, which were used to interrogate the census data. Using these categories, the data presented showed that, in aggregate, the size of the HSLF grew in the period 2001-06. In Victoria, the workforce grew from 72 000 to 89 000, an increase of 23 per cent in the five-year period 2001-06. The 44 per cent growth in the Queensland workforce was almost twice that of Victoria for the same period when it grew from 53 000 to 77 000. This aggregate data was then split to distinguish between workers who worked on 'new build' housing and those who worked on 'alterations and additions'. The results of this splitting showed that there had been growth in both sub-sectors. The rate of growth in the alterations and additions sub-sector was greater than for the new build sector, although this growth was from a lower base
Novel mutations in the BRCA1 and BRCA2 genes in Iranian women with early-onset breast cancer
BACKGROUND:
Breast cancer is the most common female malignancy and a major cause of death in middle-aged women. So far, germline mutations in the BRCA1 and BRCA2 genes in patients with early-onset breast and/or ovarian cancer have not been identified within the Iranian population.
METHODS:
With the collaboration of two main centres for cancer in Iran, we obtained clinical information, family history and peripheral blood from 83 women under the age of 45 with early-onset breast cancer for scanning of germline mutations in the BRCA1 and BRCA2 genes. We analysed BRCA1 exons 11 and BRCA2 exons 10 and 11 by the protein truncation test, and BRCA1 exons 2, 3, 5, 13 and 20 and BRCA2 exons 9, 17, 18 and 23 with the single-strand conformation polymorphism assay on genomic DNA amplified by polymerase chain reaction.
RESULTS:
Ten sequence variants were identified: five frameshifts (putative mutations – four novel); three missense changes of unknown significance and two polymorphisms, one seen commonly in both Iranian and British populations.
CONCLUSIONS
Identification of these novel mutations suggests that any given population should develop a mutation database for its programme of breast cancer screening. The pattern of mutations seen in the BRCA genes seems not to differ from other populations studied. Early-onset breast cancer (less than 45 years) and a limited family history is sufficient to justify mutation screening with a detection rate of over 25% in this group, whereas sporadic early-onset breast cancer (detection rate less than 5%) is unlikely to be cost-effective
Environmental Dependence of the Fundamental Plane of Galaxy Clusters
Galaxy clusters approximate a planar (FP) distribution in a three-dimensional
parameter space which can be characterized by optical luminosity, half-light
radius, and X-ray luminosity. Using a high-quality catalog of cluster
redshifts, we find the nearest neighbor cluster for those common to an FP study
and the cluster catalog. Examining scatter about the FP, we find 99.2%
confidence that it is dependent on nearest neighbor distance. Our study of
X-Ray clusters finds that those with high central gas densities are
systematically closer to neighbor clusters. If we combine results here with
those of Fritsch and Buchert, we find an explanation for some of our previous
conclusions: Clusters in close proximity to other clusters are more likely to
have massive cooling flows because they are more relaxed and have higher
central gas densities.Comment: Accepted for publication in Astrophysical Journal Letters. Moderate
revisions, including more statistical analysis and discussion. Latex, 7 page
Synchronized pulse control of decoherence
We present a new strategy for multipulse control over decoherence. When a
two-level system interacts with a reservoir characterized by a specific
frequency, we find that the decoherence is effectively suppressed by
synchronizing the pulse-train application with the dynamical motion of the
reservoir.Comment: 14 pages, 8 figure
Sex Cord-Gonadal Stromal Tumor of the Rete Testis
A 34-year-old tetraplegic patient with suppurative epididymitis was found on follow-up examination and ultrasonography to have a testicular mass. The radical orchiectomy specimen contained an undifferentiated spindled sex cord-stromal tumor arising in the rete testis. Testicular sex cord-stromal tumors are far less common than germ cell neoplasms and are usually benign. The close relationship between sex cords and ductules of the rete testis during development provides the opportunity for these uncommon tumors to arise anatomically within the rete tesis. This undifferentiated sex cord-stromal tumor, occurring in a previously unreported location, is an example of an unusual lesion mimicking an intratesticular malignant neoplasm
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