2,320 research outputs found
How to let go: pectin and plant cell adhesion.
This is the final version of the article. It first appeared from Frontiers via http://dx.doi.org/10.3389/fpls.2015.00523Plant cells do not, in general, migrate. They maintain a fixed position relative to their neighbors, intimately linked through growth and differentiation. The mediator of this connection, the pectin-rich middle lamella, is deposited during cell division and maintained throughout the cell's life to protect tissue integrity. The maintenance of adhesion requires cell wall modification and is dependent on the actin cytoskeleton. There are developmental processes that require cell separation, such as organ abscission, dehiscence, and ripening. In these instances, the pectin-rich middle lamella must be actively altered to allow cell separation, a process which also requires cell wall modification. In this review, we will focus on the role of pectin and its modification in cell adhesion and separation. Recent insights gained in pectin gel mechanics will be discussed in relation to existing knowledge of pectin chemistry as it relates to cell adhesion. As a whole, we hope to begin defining the physical mechanisms behind a cells' ability to hang on, and how it lets go.The writing of this review was carried out with the help of grant BB-L002884-1 (BBSRC, UK)
Identification of rare nonsynonymous variants in SYNE1/CPG2 in bipolar affective disorder
Background: Bipolar affective disorder (BPD) is a severe
mood disorder with a prevalence of ∼ 1.5% in the
population. The pathogenesis of BPD is poorly understood;
however, a strong heritable component has been identified.
Previous genome-wide association studies have indicated a
region on 6q25, coding for the SYNE1 gene, which increases
disease susceptibility. SYNE1 encodes the synaptic nuclear
envelope protein-1, nesprin-1. A brain-specific splice variant
of SYNE1, CPG2 encoding candidate plasticity gene 2, has
been identified. The intronic single-nucleotide
polymorphism with the strongest genome-wide significant
association in BPD, rs9371601, is present in both SYNE1
and CPG2. / Methods: We screened 937 BPD samples for genetic
variation in SYNE1 exons 14–33, which covers the CPG2
region, using high-resolution melt analysis. In addition, we
screened two regions of increased transcriptional activity,
one of them proposed to be the CPG2 promoter region. / Results and Conclusion: We identified six nonsynonymous
and six synonymous variants. We genotyped three rare
nonsynonymous variants, rs374866393, rs148346599 and
rs200629713, in a total of 1099 BPD samples and 1056
controls. Burden analysis of these rare variants did not show
a significant association with BPD. However, nine patients
are compound heterozygotes for variants in SYNE1/CPG2,
suggesting that rare coding variants may contribute
significantly towards the complex genetic architecture
underlying BPD. Imputation analysis in our own wholegenome
sequencing sample of 99 BPD individuals
identified an additional eight risk variants in the CPG2
region of SYNE1
Viability of the UENF popcorn improvement program based on divergence in S1 families.
With the objective of evaluating the viability of the programme of recurrent selection with popcorn of the Universidade Estadual do Norte Fluminense Darcy Ribeiro carried out in Campos dos Goytacazes and Itaocara, state of Rio de Janeiro (Brazil), 40 families that originated the second cycle were evaluated for 14 morphoagronomical characteristics and random amplified polymorphic DNA (RAPD) markers, using multivariate analysis. The analyses of variance revealed the existence of variability for most evaluated morphoagronomic traits. Clustering by Tocher's optimization method for the morphoagronomic traits of Campos dos Goytacazes formed eight groups and 16 for those of Itaocara. For the RAPD markers, 18 groups of S1 families were formed by Ward's clustering method. It is concluded that there is genetic divergence in the selected families, which allows the inference that there is sufficient variability for the continuity of the recurrent selection process with the formation of new cycles.
Fall Detection Analysis Using a Real Fall Dataset
International Conference on Soft Computing Models in Industrial and Environmental Applications (13th. 2018. San Sebastián
Caracterização morfologica e agronomica de algumas cultivares de capim-elefante.
bitstream/item/143038/1/2058.pd
Mapping of major QTLs associated with witches broom resistance in cocoa.
Edição dos resumos do 46º Congresso Nacional de Genética, Águas de Lindóia, SP, 2000
Social presence and dishonesty in retail
Self-service checkouts (SCOs) in retail can benefit consumers and retailers, providing control and autonomy to shoppers independent from staff, together with reduced queuing times. Recent research indicates that the absence of staff may provide the opportunity for consumers to behave dishonestly, consistent with a perceived lack of social presence. This study examined whether a social presence in the form of various instantiations of embodied, visual, humanlike SCO interface agents had an effect on opportunistic behaviour. Using a simulated SCO scenario, participants experienced various dilemmas in which they could financially benefit themselves undeservedly. We hypothesised that a humanlike social presence integrated within the checkout screen would receive more attention and result in fewer instances of dishonesty compared to a less humanlike agent. This was partially supported by the results. The findings contribute to the theoretical framework in social presence research. We concluded that companies adopting self-service technology may consider the implementation of social presence in technology applications to support ethical consumer behaviour, but that more research is required to explore the mixed findings in the current study.<br/
Determinants of environmental management in the red sea hotels: Personal and organizational values and contextual variables
What motivates firms to adopt environmental management practices is one of the most significant aspects in the contemporary academic debate in which the review of the existing literature yields, with an obvious contextual bias toward developed world, contested theories and inconclusive findings. Providing a unique model that brings together the individual and organizational levels of analysis on firms' adoption of environmental management practices, this study aims to provide a new insight from the context of developing world. Data from 158 Red Sea hotels reveal two identifiable dimensions of environmental management-planning and organization, and operations-that can be explained as originating from different values. Whereas organizational altruism is a powerful predictor of both dimensions, managers' personal values and organizational competitive orientation are only relevant to environmental operations. The evidence also indicates that contextual variables such as chain affiliation, hotel star rating, and size are important to explain hotels' environmental management behaviors. © 2012 ICHRIE
Erratum to: Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer
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