5,042 research outputs found

    eCHASE: Sustainable Exploitation of Electronic Cultural Heritage

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    Europe’s digital cultural heritage content has tremendous exploitation potential in applications such as Education, Publishing, e-Commerce, Public Access and Tourism. Value is hugely amplified if the content can be aggregated, repurposed and distributed at a European level. The eCHASE project seeks to demonstrate that public-private partnerships between content holders and commercial service providers can create new services and a sustainable business based on access and exploitation of digital cultural heritage content. This paper describes these issues and introduces the eCHASE architecture that is being developed to showcase the business models created for the project

    Cost of Salmonella infections in Australia, 2015

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    Copyright Ó, International Association for Food Protection Gastroenteritis caused from infections with Salmonella enterica (salmonellosis) causes significant morbidity in Australia. In addition to acute gastroenteritis, approximately 8.8% of people develop irritable bowel syndrome (IBS) and 8.5% of people develop reactive arthritis (ReA). We estimated the economic cost of salmonellosis and associated sequel illnesses in Australia in a typical year circa 2015. We estimated incidence, hospitalizations, other health care usage, absenteeism, and premature mortality for four age groups using a variety of complementary data sets. We calculated direct costs (health care) and indirect costs (lost productivity and premature mortality) by using Monte Carlo simulation to estimate 90% credible intervals (CrI) around our point estimates. We estimated that 90,833 cases, 4,312 hospitalizations, and 19 deaths occurred from salmonellosis in Australia circa 2015 at a direct cost of AUD 23.8 million (90% CrI, 19.3 to 28.9 million) and a total cost of AUD 124.4 million (90% CrI, 107.4 to 143.1 million). When IBS and ReA were included, the estimated direct cost was 35.7 million (90% CrI, 29.9 to 42.7 million) and the total cost was AUD 146.8 million (90% CrI, 127.8 to 167.9 million). Foodborne infections were responsible for AUD 88.9 million (90% CrI, 63.9 to 112.4 million) from acute salmonellosis and AUD 104.8 million (90% CrI, 75.5 to 132.3 million) when IBS and ReA were included. Targeted interventions to prevent illness could considerably reduce costs and societal impact from Salmonella infections and sequel illnesses in Australia

    In vivo label-free photoacoustic microscopy of cell nuclei by excitation of DNA and RNA

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    Imaging of cell nuclei plays a critical role in cancer diagnosis and prognosis. To image noninvasively cell nuclei in vivo without staining, we developed UV photoacoustic microscopy (UV-PAM), in which 266nm wavelength UV light excites unlabeled DNA and RNA in cell nuclei to produce photoacoustic waves. We applied UV-PAM to ex vivo imaging of cell nuclei in a mouse lip and a mouse small intestine and to in vivo imaging of the cell nuclei in the mouse skin. The UV-PAM images of unstained cell nuclei match the optical micrographs of the histologically stained cell nuclei. Given intrinsic optical contrast and high spatial resolution, in vivo label-free UV-PAM has potential for unique biological and clinical application

    Diffusion of H in Pd-Ag Alloys (423 to 523 K)

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    Abstract H diffusion constants have been determined from steadystate fluxes through Pd-Ag alloy membranes. The upstream side is maintained at a nearly constant p up an

    RELIABILITY ANALYSIS OF A STEEL BEAM USING THE MONTE CARLO METHOD

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    This paper aims to show the feasibility of structural analysis in steel beams, based on the precepts of reliability. We assessed the reliability and security of a steel I-beam profile (I 254 (10”) x 37,7), MR250, subject to an applied bending moment. The purpose was to evaluate the appropriateness of the component in handling specific project stresses. First we provide a dimensioning analysis based on Brazilian structural standards and then a verification of the beam’s relative safety, in terms of the reliability index ï¢ . The adopted failure function is related to gross and net areas of the flange, submitted to traction stresses. The system’s reliability index, constituted by the failure function is also determined. Considering the statistical results, the failure rate in the structure, demonstrates that the solicited project loadings are sustained, also determining the capacity of the structure to exceed the applied load, while maintaining structural safety of the steel beam. In the reliability analysis, the use of randomized integer generation, assisted by computational resources (Mathcad), makes it feasible to infinitely test the metallic structure. The Monte Carlo method was used, based on determined probability distributions (involved variables), to obtain the probability of structural failure. The random variables used in the reliability analysis, are delineated by the Joint Committee for Structural Safety (JCSS)

    Aerosol Retrievals from Different Polarimeters During the ACEPOL Campaign Using a Common Retrieval Algorithm

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    In this paper, we present aerosol retrieval results from the ACEPOL (Aerosol Characterization from Polarimeter and Lidar) campaign, which was a joint initiative between NASA and SRON the Netherlands Institute for Space Research. The campaign took place in OctoberNovember 2017 over the western part of the United States. During ACEPOL six different instruments were deployed on the NASA ER-2 high-altitude aircraft, including four multi-angle polarimeters (MAPs): SPEX airborne, the Airborne Hyper Angular Rainbow Polarimeter (AirHARP), the Airborne Multi-angle SpectroPolarimetric Imager (AirMSPI), and the Research Scanning Polarimeter (RSP). Also, two lidars participated: the High Spectral Resolution Lidar-2 (HSRL-2) and the Cloud Physics Lidar (CPL). Flights were conducted mainly for scenes with low aerosol load over land, but some cases with higher AOD were also observed. We perform aerosol retrievals from SPEX airborne, RSP (410865 nm range only), and AirMSPI using the SRON aerosol retrieval algorithm and compare the results against AERONET (AErosol RObotic NETwork) and HSRL-2 measurements (for SPEX airborne and RSP). All three MAPs compare well against AERONET for the aerosol optical depth (AOD), with a mean absolute error (MAE) between 0.014 and 0.024 at 440 nm. For the fine-mode effective radius the MAE ranges between 0.021 and 0.028 m. For the comparison with HSRL-2 we focus on a day with low AOD (0.020.14 at 532 nm) over the California Central Valley, Arizona, and Nevada (26 October) as well as a flight with high AOD (including measurements with AOD>1.0 at 532 nm) over a prescribed forest fire in Arizona (9 November). For the day with low AOD the MAEs in AOD (at 532 nm) with HSRL-2 are 0.014 and 0.022 for SPEX and RSP, respectively, showing the capability of MAPs to provide accurate AOD retrievals for the challenging case of low AOD over land. For the retrievals over the smoke plume a reasonable agreement in AOD between the MAPs and HSRL-2 was also found (MAE 0.088 and 0.079 for SPEX and RSP, respectively), despite the fact that the comparison is hampered by large spatial variability in AOD throughout the smoke plume. A good comparison is also found between the MAPs and HSRL-2 for the aerosol depolarization ratio (a measure of particle sphericity), with an MAE of 0.023 and 0.016 for SPEX and RSP, respectively. Finally, SPEX and RSP agree very well for the retrieved microphysical and optical properties of the smoke plume
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