NOVO REGISTRO DE FABACEAE (CAESALPINIOIDEAE) PARA O BRASIL: Dimorphandra davisii SPRAGUE & SANDWITH

The study presents the first occurrence of Dimorphandra davisii Sprague & Sandwith from Brazil, a species previously known only in Guyana and Venezuela. After examining the INPA and NY herbarium collections, it was verified that the species was collected in 1986 and occurs in the municipality of Presidente Figueiredo, in the state of Amazonas, but never registered for the Brazilian flora. The record of the species increases the floristic data of the Brazilian Amazon and contributes to the better knowledge of Dimorphandra in Brazil.Keywords: Caesalpinieae; Distribution of species; Amazon Rainforest; Taxonomy.O estudo apresenta a primeira ocorrência de Dimorphandra davisii Sprague et Sandwith do Brasil, uma espécie conhecida apenas na Guiana e Venezuela. Depois de examinar as coleções dos herbários INPA e NY, verificou-se que a espécie foi coletada em 1986 e ocorre no município de Presidente Figueiredo, no estado do Amazonas, mas nunca registrada para a flora brasileira. O registro da espécie aumenta os dados florísticos da Amazônia brasileira e contribui para o melhor conhecimento de Dimorphandra no Brasil.Palavras-chave: Caesalpinieae, Distribuição de espécies, Floresta Amazônica, Taxonomia

Multi-reference approach to the calculation of photoelectron spectra including spin-orbit coupling

X-ray photoelectron spectra provide a wealth of information on the electronic structure. The extraction of molecular details requires adequate theoretical methods, which in case of transition metal complexes has to account for effects due to the multi-configurational and spin-mixed nature of the many-electron wave function. Here, the Restricted Active Space Self-Consistent Field method including spin-orbit coupling is used to cope with this challenge and to calculate valence and core photoelectron spectra. The intensities are estimated within the frameworks of the Dyson orbital formalism and the sudden approximation. Thereby, we utilize an efficient computational algorithm that is based on a biorthonormal basis transformation. The approach is applied to the valence photoionization of the gas phase water molecule and to the core ionization spectrum of the $\text{[Fe(H}_2\text{O)}_6\text{]}^{2+}$ complex. The results show good agreement with the experimental data obtained in this work, whereas the sudden approximation demonstrates distinct deviations from experiments

The efficacy of a compassion-focused therapy–based intervention in reducing psychopathic traits and disruptive behavior: a clinical case study with a juvenile detainee

Conduct disorder (CD) is the most diagnosed psychopathological disorder in juvenile detainees. The presence of a CD diagnosis, especially when associated with psychopathic traits, contributes to a poor prognosis, high recidivism rates, and low responsivity to treatment in these youth. Although group intervention programs have proven to be effective in decreasing antisocial behavior, studies testing their efficacy in reducing psychopathic traits are scarce and limited. Moreover, there is a lack of research focused on the efficacy of individual treatment approaches specifically designed to reduce psychopathic traits and disruptive behavior in juvenile detainees. Compassion-focused therapy (CFT) shows promising results in the treatment of several psychopathological disorders. Besides, there is some theoretical support to consider CFT a suitable approach to treating juvenile detainees. However, there are no treatment programs based on CFT that are designed to target psychopathic traits and disruptive behavior in these youth. Consequently, treatment outcome research in this area is absent. This clinical case study presents the treatment of a juvenile detainee with CD, a high psychopathic profile, and a very high risk for criminal recidivism using the PSYCHOPATHY.COMP program (a 20-session individual CFT program), which was specially designed to reduce psychopathic traits and disruptive behavior. The treatment outcome data revealed a significant reduction in psychopathic traits and disruptive behavior. The treatment gains were maintained and/or increased over time (3 months after program completion). This clinical case study demonstrates the feasibility and efficacy of the PSYCHOPATHY.COMP program in reducing psychopathic traits and disruptive behavior in a juvenile detainee.This research has been supported by the first author PhD Grant (SFRH/BD/99795/2014), sponsored by the Portuguese Foundation for Science and Technology (FCT). This work was also financed by FEDER—European Social Fund—through the COMPETE 2020-Operational Program for Competitiveness and Internationalization (POCI), and by Portuguese funds through FCT in the framework of the project POCI-01-0145-FEDER-016724

Application of the zero-range potential model to positron annihilation on molecules

In this paper we use a zero-range potential (ZRP) method to model positron interaction with molecules. This allows us to investigate the effect of molecular vibrations on positron-molecule annihilation using the van der Waals dimer Kr2 as an example. We also use the ZRP to explore positron binding to polyatomics and examine the dependence of the binding energy on the size of the molecule for alkanes. We find that a second bound state appears for a molecule with ten carbons, similar to recent experimental evidence for such a state emerging in alkanes with twelve carbons.Comment: 14 pages, 6 figures, to be published in Nuclear Instruments and Methods

The Mutation without childrenrgl Causes Ecdysteroid Deficiency in Third-Instar Larvae of Drosophila melanogaster

Larvae homozygous for the recessive lethal allele gene, located in polytene chromosomal region 97F, consists of 11 exons. A 6.8-kb transcript is expressed throughout development but is absent in the mutant gene encodes a protein of 187 kDa. Eight zinc fingers of the C2–C2 type point to a possible function as a transcription factor. The protein shows considerable homology to human proteins which have been implicated in both mental retardation and a leukemia/lymphoma syndrome

Normalization of prostate specific antigen in patients treated with intensity modulated radiotherapy for clinically localized prostate cancer

<p>Abstract</p> <p>Background</p> <p>The purpose of this study was to determine the expected time to prostate specific antigen (PSA) normalization with or without neoadjuvant androgen deprivation (NAAD) therapy after treatment with intensity modulated radiotherapy (IMRT) for patients with clinically localized prostate cancer.</p> <p>Methods</p> <p>A retrospective cohort research design was used. A total of 133 patients with clinical stage T1c to T3b prostate cancer (2002 AJCC staging) treated in a community setting between January 2002 and July 2005 were reviewed for time to PSA normalization using 1 ng/mL and 2 ng/mL as criteria. All patients received IMRT as part of their management. Times to PSA normalization were calculated using the Kaplan-Meier method. Significance was assessed at p < 0.05.</p> <p>Results</p> <p>Fifty-six of the 133 patients received NAAD (42.1%). Thirty-one patients (23.8%) received radiation to a limited pelvic field followed by an IMRT boost, while 99 patients received IMRT alone (76.2%). The times to serum PSA normalization < 2 ng/mL when treated with or without NAAD were 298 ± 24 and 302 ± 33 days (mean ± SEM), respectively (p > 0.05), and 303 ± 24 and 405 ± 46 days, respectively, for PSA < 1 ng/mL (p < 0.05). Stage T1 and T2 tumors had significantly increased time to PSA normalization < 1 ng/mL in comparison to Stage T3 tumors. Also, higher Gleason scores were significantly correlated with a faster time to PSA normalization < 1 ng/mL.</p> <p>Conclusions</p> <p>Use of NAAD in conjunction with IMRT leads to a significantly shortened time to normalization of serum PSA < 1 ng/mL in patients with clinically localized prostate cancer.</p

A pena de morte da pessoa jurídica na lei de crimes ambientais

O Estado tem o papel de impedir a efetivação de danos ambientais e, quando não for possível, deve punir os responsáveis. A respeito das sanções dispostas na Lei de Crimes Ambientais, uma em especial é o objeto de estudo deste trabalho. Trata-se da possibilidade de liquidação forçada de pessoas jurídicas, nos termos do artigo 24 da referida legislação. Como ficará claro após a apreciação desta monografia, tal previsão - conhecida na doutrina como pena de morte da pessoa jurídica - é inconstitucional. Isso ocorre em virtude da violação de princípios constitucionais, tais como o da legalidade e da individualização da pena. Ademais, além das graves ofensas à Carta Magna, se mostra como uma política desastrada, uma vez que não pune adequadamente, não permite a reparação do dano ambiental e, ainda, prejudica a coletividade. Desse modo, viola também um importante princípio do Direito Ambiental: o princípio do poluidor pagador. Em que pese tantas objeções, a liquidação forçada da Lei de Crimes Ambientais seque em vigor e ainda serviu de inspiração para a dissolução forçada prevista na Lei Anticorrupção. A presente monografia debate a temática através do estudo da legislação brasileira e da doutrina pertinentes ao caso.The state has the obligation to prevent the execution of environmental damage and, where not possible, to punish those responsible. Regarding the sanctions laid out in the Environmental Crimes Law, one in particular is the object of study of this work. It is the possibility of forced liquidation of legal entities, pursuant to art. 24 of said law. As will be clear after the consideration of this monograph, such a prediction - known in the doctrine as the death penalty legal person - is unconstitutional. This is because of the violation of constitutional principles, such as the legality and individualization of punishment. Moreover, in addition to serious offenses against the Constitution, shown as a clumsy policy, since it does not adequately punish, does not allow the repair of environmental damage and also harms the community. This way, also violates an important principle of environmental law: the polluter pays principle. Despite many objections, the forced liquidation of the Environmental Crimes Law dry in force and also served as inspiration for the forced dissolution provided for in the Anti-Corruption Law. This monograph discusses the issue by studying the Brazilian legislation and the doctrine relevant to the case

Stellar Kinematics of the Andromeda II Dwarf Spheroidal Galaxy

We present kinematical profiles and metallicity for the M31 dwarf spheroidal (dSph) satellite galaxy Andromeda II (And II) based on Keck DEIMOS spectroscopy of 531 red giant branch stars. Our kinematical sample is among the largest for any M31 satellite and extends out to two effective radii (r_eff = 5.3' = 1.1 kpc). We find a mean systemic velocity of -192.4+-0.5 km/s and an average velocity dispersion of sigma_v = 7.8+-1.1 km/s. While the rotation velocity along the major axis of And II is nearly zero (<1 km/s), the rotation along the minor axis is significant with a maximum rotational velocity of v_max=8.6+-1.8 km/s. We find a kinematical major axis, with a maximum rotational velocity of v_max=10.9+-2.4 km/s, misaligned by 67 degrees to the isophotal major axis. And II is thus the first dwarf galaxy with evidence for nearly prolate rotation with a v_max/sigma_v = 1.1, although given its ellipticity of epsilon = 0.10, this object may be triaxial. We measured metallicities for a subsample of our data, finding a mean metallicity of [Fe/H] = -1.39+- 0.03 dex and an internal metallicity dispersion of 0.72+-0.03 dex. We find a radial metallicity gradient with metal-rich stars more centrally concentrated, but do not observe a significant difference in the dynamics of two metallicity populations. And II is the only known dwarf galaxy to show minor axis rotation making it a unique system whose existence offers important clues on the processes responsible for the formation of dSphs.Comment: 14 pages, 10 figures, 4 tables, accepted for publication in Ap