38 research outputs found

    Projecto de formação e investigação em educação de infância (PFIEI) : relatório do projecto promover a qualidade em educação pré-escolar (PQEPE)

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    Relatório elaborado no âmbito do "Projecto de Formação e Investigação em Educação de Infância (PFIEI)".Com este relatório pretendemos dar a conhecer os resultados de um estudo de avaliação do impacto da brochura Sabe o que é a Educação Pré-Escolar?. Este estudo exploratório, realizado no ano lectivo 2006/2007, envolveu 14 intervenientes educativos no âmbito da Educação de Infância a exercer as suas funções na zona urbana da região de Leiria e Batalha. Recorrendo à utilização do Questionário de Identificação e Caracterização da Organização e Funcionamento dos Estabelecimentos de Educação Pré-Escolar, à brochura Sabe o que é a Educação Pré-Escolar? e a diálogos informais, este estudo contemplou dois momentos distintos: antes e após a leitura da brochura. Os resultados revelam a pertinência da brochura na mudança e clarificação de ideias de diferentes intervenientes educativos na Educação Pré-Escolar no que respeita à organização, funcionamento e tutela e à qualidade e avaliação na educação pré-escolar

    Diversidade genética estimada com marcadores entre sequências simples repetidas em cultivos comerciais de Cupuaçuzeiro

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    RESUMO: Quinze primers ISSR (entre sequências simples repetidas) foram utilizados para avaliar a diversidade genética entre e dentro de pomares comerciais de Theobroma grandiflorum (Willd. ex Spreng.) K. Schum. Para isso, foram analisados sessenta indivíduos, distribuídos nos três cultivos. Um total de 102 bandas foi amplificado, com uma porcentagem de 52,0% de polimorfismo em nível de espécie e média de 6,8 alelos por primer ISSR. A média do Índice de Conteúdo Polimórfico (PIC) foi de 0,55. Em relação aos índices de diversidade gênica de Nei (H) e de Shannon (I), os cultivos analisados apresentaram os valores: SAR H = 0,114 e I = 0,177; SSL H = 0,108 e I = 0,162 e SEC H = 0,104 e I = 0,156, considerados valores de moderados a baixos. A AMOVA revelou 34,91% da variância total entre os cultivos e 65,09% dentro deles. Os marcadores moleculares ISSR revelaram que há diversidade genética dentro de cada cultivo comercial estudado, portanto é possível selecionar genótipos superiores que poderão ser utilizados para originar cultivos mais uniformes. Esse resultado tem sido considerado de grande relevância, por fornecer ferramentas para a implementação de programas de melhoramento e delineamento de estratégias de conservação ex situ e in situ

    The management of acute venous thromboembolism in clinical practice. Results from the European PREFER in VTE Registry

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    Venous thromboembolism (VTE) is a significant cause of morbidity and mortality in Europe. Data from real-world registries are necessary, as clinical trials do not represent the full spectrum of VTE patients seen in clinical practice. We aimed to document the epidemiology, management and outcomes of VTE using data from a large, observational database. PREFER in VTE was an international, non-interventional disease registry conducted between January 2013 and July 2015 in primary and secondary care across seven European countries. Consecutive patients with acute VTE were documented and followed up over 12 months. PREFER in VTE included 3,455 patients with a mean age of 60.8 ± 17.0 years. Overall, 53.0 % were male. The majority of patients were assessed in the hospital setting as inpatients or outpatients (78.5 %). The diagnosis was deep-vein thrombosis (DVT) in 59.5 % and pulmonary embolism (PE) in 40.5 %. The most common comorbidities were the various types of cardiovascular disease (excluding hypertension; 45.5 %), hypertension (42.3 %) and dyslipidaemia (21.1 %). Following the index VTE, a large proportion of patients received initial therapy with heparin (73.2 %), almost half received a vitamin K antagonist (48.7 %) and nearly a quarter received a DOAC (24.5 %). Almost a quarter of all presentations were for recurrent VTE, with >80 % of previous episodes having occurred more than 12 months prior to baseline. In conclusion, PREFER in VTE has provided contemporary insights into VTE patients and their real-world management, including their baseline characteristics, risk factors, disease history, symptoms and signs, initial therapy and outcomes

    613 cases of splenic rupture without risk factors or previously diagnosed disease: a systematic review

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    Background Rupture of the spleen in the absence of trauma or previously diagnosed disease is largely ignored in the emergency literature and is often not documented as such in journals from other fields. We have conducted a systematic review of the literature to highlight the surprisingly frequent occurrence of this phenomenon and to document the diversity of diseases that can present in this fashion. Methods Systematic review of English and French language publications catalogued in Pubmed, Embase and CINAHL between 1950 and 2011. Results We found 613 cases of splenic rupture meeting the criteria above, 327 of which occurred as the presenting complaint of an underlying disease and 112 of which occurred following a medical procedure. Rupture appeared to occur spontaneously in histologically normal (but not necessarily normal size) spleens in 35 cases and after minor trauma in 23 cases. Medications were implicated in 47 cases, a splenic or adjacent anatomical abnormality in 31 cases and pregnancy or its complications in 38 cases. The most common associated diseases were infectious (n = 143), haematologic (n = 84) and non-haematologic neoplasms (n = 48). Amyloidosis (n = 24), internal trauma such as cough or vomiting (n = 17) and rheumatologic diseases (n = 10) are less frequently reported. Colonoscopy (n = 87) was the procedure reported most frequently as a cause of rupture. The anatomic abnormalities associated with rupture include splenic cysts (n = 6), infarction (n = 6) and hamartomata (n = 5). Medications associated with rupture include anticoagulants (n = 21), thrombolytics (n = 13) and recombinant G-CSF (n = 10). Other causes or associations reported very infrequently include other endoscopy, pulmonary, cardiac or abdominal surgery, hysterectomy, peliosis, empyema, remote pancreato-renal transplant, thrombosed splenic vein, hemangiomata, pancreatic pseudocysts, splenic artery aneurysm, cholesterol embolism, splenic granuloma, congenital diaphragmatic hernia, rib exostosis, pancreatitis, Gaucher's disease, Wilson's disease, pheochromocytoma, afibrinogenemia and ruptured ectopic pregnancy. Conclusions Emergency physicians should be attuned to the fact that rupture of the spleen can occur in the absence of major trauma or previously diagnosed splenic disease. The occurrence of such a rupture is likely to be the manifesting complaint of an underlying disease. Furthermore, colonoscopy should be more widely documented as a cause of splenic rupture

    Improving HF communications efficiency using evolved data rate change algorithms

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    As comunicações na banda das altas frequências (HF) têm evoluído tecnologicamente, desde o final dos anos 80, sendo esta evolução motivada pela potencial robustez desta forma de comunicação em situações de catástrofe e de emergência, e pelo custo de manutenção e implementação das comunicações via satélite. Apesar do reaparecimento do interesse nas comunicações HF, existem vários desafios envolvidos, como a operação rádio com relações sinal-ruido (SNR) tipicamente muito baixas e variação do sinal devido a mudanças frequentes na camada da Ionosfera. Para lidar com as variações do canal em HF, surgiram várias tecnologias como os algoritmos de seleção automática do débito binário (DRC). As soluções existentes (Trinder e RapidM) foram estudadas, e com base nas vulnerabilidades detetadas, foram propostas versões melhoradas de ambos os algoritmos: Avoiding Cut-Off State (ACOS) e Bit Error Optimization (BEO). A primeira proposta reduz o número de ocorrências de corte na ligação (correspondente a taxas de erro de bit superiores a 10-3) e a segunda aumenta a disponibilidade da ligação e elimina as oscilações de débito binário. Quando comparadas com as versões originais, ambas as propostas demonstram melhores desempenhos, seja num sistema de simulação ou em condições reais de propagação.High frequency (HF) band communications have undergone a remarkable technologic evolution, since the 80s, motivated by their potential robustness to catastrophic and emergency situations, and by the high costs involved in implementing and maintaining satellite links. Despite the renewed interest on HF communications, there are a lot of challenges involved, like the operation with very low signal-to-noise ratios (SNR) and signal variation due to the frequent changes in the Ionosphere constitution. In order to deal with the variability of the HF channel, several technologies have emerged like the Data Rate Change (DRC) algorithms. Former DRC algorithms solutions were studied (Trinder and RapidM), and based on their vulnerabilities, improved versions were proposed for both algorithms: Avoiding Cut-Off State (ACOS) and Bit Error Optimization (BEO). The first proposal reduces the occurrences of link cut-offs (corresponding to bit error rates higher than 10-3), and the second increases the link availability and eliminates data rate oscillations. When compared to the original versions of the algorithms, both proposals showed significant performance improvements, either when evaluated in a simulation environment, or in real field propagation tests.info:eu-repo/semantics/publishedVersio
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