159 research outputs found

    A contribuição das referências dos planos de ensino para a caracterização de domínios: um estudo no curso de Biocombustível do Centro Paula Souza

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    This research analyzes the bibliographical references indicated in the courses taught in two units of the Technological Course in Biofuels at the Centro Paula Souza in order to characterize the scientific domain founding the training of their students. In addition, this study maps the citation network by block of courses – basic and professional-, identifying the theoretical-methodological proximity between the two units. The corpus of analysis consists of 284 references retrieved at the Fatec Jaboticabal unit, and 238 references at the Fatec Araçatuba unit. Bibliometric relational citation analysis procedures associated with Social Network Analysis were adopted. As a result, there was a moderate overlap of citation identities between the two units for the group of subjects of the basic axis and the group of subjects of Agricultural Production Process, Management, Final Undergraduate Project and Transversal subjects. On the other hand, the overlap was less significant for the Biofuel Production Processes axis. The study concluded that the adopted methodology allowed to characterize the scientific domain founding of the technologist's training in Biofuels, in its two units, as well as to identify their similarities and specificities regarding their citation identities, constituted from the references adopted in the courses.Esta investigación analiza las referencias bibliográficas señaladas en los cursos en dos unidades del Curso Tecnológico en Biocombustibles del Centro Paula Souza con el fin de caracterizar el dominio científico que fundamenta la formación de sus estudiantes. Además, este estudio mapea la red de citas por bloque de cursos - básico y profesional-, identificando la proximidad teórico-metodológica entre las dos unidades. El corpus de análisis consta de 284 referencias recuperadas en la unidad Fatec Jaboticabal y 238 referencias en la unidad Fatec Araçatuba. Se adoptan procedimientos bibliométricos de análisis de citas relacionales asociados con el análisis de redes sociales. Como resultado, hubo una moderada superposición de identidades de citación entre las dos unidades didácticas para el grupo de cursos del eje básico y el grupo de cursos de Procesos Productivos Agropecuarios, Gestión, Trabajo Fin de Grado y cursos Transversales. Por otro lado, la superposición fue menos significativa para el eje Procesos de producción de biocombustibles. El estudio concluyó que la metodología adoptada permitió caracterizar el dominio científico fundacional de la formación del tecnólogo en Biocombustibles, en sus dos unidades didácticas, así como identificar sus similitudes y especificidades en cuanto a sus identidades de citación, constituidas a partir de las referencias adoptadas en los cursos.Esta pesquisa analisa as referências adotadas nas disciplinas ministradas em duas unidades do Curso Tecnológico em Biocombustíveis do Centro Paula Souza a fim de caracterizar o domínio científico fundante da formação dos seus egressos. Ainda, mapeia a rede de citações por bloco de disciplinas – básicas e profissionais-, identificando a proximidade teórico-metodológica entre as duas unidades. O corpus de análise é constituído por 284 referências recuperadas para a unidade Fatec Jaboticabal e 238 referências para a unidade Fatec Araçatuba. Adotam-se procedimentos bibliométricos de análise de citação relacional associados à Análise de Redes Sociais. Como resultados observou-se uma sobreposição moderada de identidade de citação entre as duas unidades de ensino para o grupo de disciplinas do eixo básico e o grupo de disciplinas de Processo de Produção Agrícola, Gestão, Projeto de Trabalho de Graduação e Transversais. Por outro lado, a sobreposição mostrou-se menos significativa para o eixo de disciplinas Processos de Produção de Biocombustíveis. Conclui-se que a metodologia adotada permitiu caracterizar o domínio científico fundante da formação do tecnólogo em Biocombustíveis, em suas duas unidades de ensino, assim como identificar suas similaridades e especificidades quanto às suas identidades de citação, constituídas a partir das referências adotadas nas disciplinas

    Color stability, surface roughness and microhardness of composites submitted to mouthrinsing action

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    OBJECTIVE:The purpose of this study was to evaluate the effect of mouth rinse solutions on color stability, surface roughness and microhardness of two composite resins. MATERIAL AND METHODS: Fifty test specimens of each composite (Filtek Z250 and Z350; 3M ESPE) were made using a teflon matrix (12x2 mm). Color, surface roughness and Knoop microhardness baseline measurements of each specimen were made and specimens (n=10) were immersed in 5 mouth rinse solutions: G1: distilled water (control), G2: Plax Classic, G3: Plax alcohol-free; G4: Periogard, and G5: Listerine. Final measurements of color, roughness and microhardness were performed and the results submitted to statistical analysis (2-way ANOVA, Bonferroni s test;

    Combretum leprosum Mart. (Combretaceae): Potential as an antiproliferative and anti-inflammatory agent

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    AbstractEthnopharmacological relevanceCombretum leprosum is a species that is popularly used in Brazil as a healing agent to treat skin problems and lesions. In this study we investigated the possible potential of this extract to treat inflammatory and hyperproliferative skin conditions.Materials and methodsClassical models of skin inflammation such as TPA- and croton oil-induced mouse ear oedema were applied in order to verify the potential topical anti-inflammatory activity of the ethanolic extract from flowers of Combretum leprosum.ResultsTopical application of ethanolic extract promoted a dose-dependent inhibition of phorbol ester-induced ear oedema, reduced myeloperoxidase activity and IL-6 tissue levels with inhibition comparable to dexamethasone (positive control). Histological and immunohistochemical analysis revealed that ethanolic extract also suppressed cell infiltration. Ethanolic extract altered inflammatory parameters on a chronic skin inflammation model induced by repeated applications of croton oil, decreasing ear oedema, epidermal hyperproliferation and cell infiltration. In addition, immunohistochemical analysis showed that the extract decreased PCNA expression on the epidermis.ConclusionTaken together, these results suggest that the extract from flowers of Combretum leprosum could be considered as a new potential tool for the treatment of several skin inflammatory diseases since it reversed the skin inflammatory and hyperproliferative process in a very significant manner. Further investigations are needed in order to verify the cellular mechanism and safety of Combretum leprosum extract

    Pesquisadores de maior visibilidade em Organização e Representação do Conhecimento: um estudo a partir da análise de cocitações

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    The most visible researchers in Knowledge Organization and Representation were identified, from the perspective of Brazilian researchers, based on cocitations from the papers presented in the last five meetings of the Encontros Nacionais de Pesquisa of the Associação Nacional de Pesquisa e Pós- Graduação em Ciência da Informação (ENANCIBs) from 2003 to 2008. First, the total number of references was identified, a total of 134 articles. Second, a citation analysis was conducted, being considered the most cited authors those who received 12 citations or more, which resulted in 31 most cited authors. Third, the Pajek software was used for the construction of the co-citation network and, thereafter, some indicators were calculated with the Ucinet software, which describe the structure and cohesion of the generated network, and, particularly, its density, and its degree of centrality, betweenness and proximity. The high cohesion of the network and the compliance between the most co-cited authors and the calculated indicators were verified.Se identifican los investigadores con mayor visibilidad en Organización y Representación del Conocimiento, desde el punto de vista de los investigadores brasileños, a partir de las cocitaciones realizadas en los artículos presentados en los cinco últimos Encontros Nacionais de Pesquisa da Associação Nacional de Pesquisa e Pós-Graduação em Ciência da Informação (ENANCIB), realizados entre 2003 y 2008. Se localizó el conjunto total de referencias, compuesto por 134 artículos y, realizado el análisis de citas, se consideraron como autores más citados a aquellos que hubieran recibido 12 citas o más: un total de 31. Seguidamente, se utilizó el software Pajek para la construcción de la red de cocitación y se calcularon, por medio del software Ucinet, algunos indicadores que describen la estructura y cohesión de la red generada, en particular su densidad y su centralidad de grado, de intermediación y de proximidad. Se verificó la alta cohesión de la red y la conformidad entre los autores más cocitados y los indicadores calculados

    Analysis of the Potential Topical Anti-Inflammatory Activity of Averrhoa carambola L. in Mice

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    Inflammatory skin disorders, such as psoriasis and atopic dermatitis, are very common in the population; however, the treatments currently available are not well tolerated and are often ineffective. Averrhoa carambola L. (Oxalidaceae) is an Asian tree that has been used in traditional folk medicine in the treatment of several skin disorders. The present study evaluates the topical anti-inflammatory effects of the crude ethanolic extract of A. carambola leaves, its hexane, ethyl acetate, and butanol fractions and two isolated flavonoids on skin inflammation. Anti-inflammatory activity was measured using a croton oil-induced ear edema model of inflammation in mice. Topically applied ethanolic extract reduced edema in a dose-dependent manner, resulting in a maximum inhibition of 73 ± 3% and an ID50 value of 0.05 (range: 0.02–0.13) mg/ear. Myeloperoxidase (MPO) activity was also inhibited by the extract, resulting in a maximum inhibition of 60 ± 6% (0.6 mg/ear). All of the fractions tested caused inhibition of edema formation and of MPO activity. Treatment with the ethyl acetate fraction was the most effective, resulting in inhibition levels of 75 ± 5 and 54 ± 8% for edema formation and MPO activity, respectively. However, treatment of mice with isolated compounds [apigenin-6-C-β-l-fucopyranoside and apigenin-6-C-(2″-O-α-l-rhamnopyranosyl)-β-l-fucopyranoside] did not yield successful results. Apigenin-6-C-(2″-O-α-l-rhamnopyranosyl)-β-l-fucopyranoside caused only a mild reduction in edema formation (28 ± 11%). Taken together, these preliminary results support the popular use of A. carambola as an anti-inflammatory agent and open up new possibilities for its use in skin disorders

    Lipid profile in schoolchildren in Vitória – Brazil

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    Introduction: The growing prevalence of obesity is currently considered the most important nutritional disorder. It is characterized, according to the World Health Organization (WHO) as a worldwide epidemic in developing and developed countries. In an associated form, there is an increasing prevalence of dyslipidaemia. Aiming to improve the current situation and prevent the progression of the epidemic, the American Academy of Pediatrics recently reinforced the need for cholesterol screening in overweight children older than two years. Objective: To determine overweight and lipid profi le in children aged between six and nine years. Methods: A descriptive, cross-sectional study with children from Vitoria, ES. For nutritional classifi cation the Z-score > + 1 SD body mass index-for-age (according to WHO / 2007) was used; for the lipid profi le the Atherosclerosis Prevention Guidelines in Childhood were used. Anthropometric measurements (weight, height, waist circumference and triceps skinfold thickness) followed the standard techniques described by WHO. Data were organized and analysed using SPSS, version 8.5 and calculated the absolute, relative and mean (SD) frequencies and the association between overweight, lipid profile and other variables is adopted as signifi cant when p < 0.05. Results: The sample comprised a total of 511 children of both sexes (46.7% male), with a mean age of 101.6 ± 11.1 months. Overweight was found in 197 (38.5%) children: overweight in 71 (13.9%) and obesity in 126 (24.6%). Total cholesterol was elevated in 167 (32.7%) as were high LDL-C (136–27%). High triglycerides were found in 21 participants (4.1%). Signifi cant association was found between waist circumference and high levels of triglycerides (p = 0.019) and HDL-C (p = 0.033). Conclusion: Excess weight of the sample investigated is considered high and its health effects are important, with an increased total cholesterol greater than 32%. The high levels of HDL-C are protectivefactors for coronary heart disease, although the lipid profi le had been changed

    Tumor fibroso solitário retroperitoneal: um relato de caso / Retroperitoneal solitary fiber tumor: a case report

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    O tumor fibroso solitário é uma neoplasia mesenquimal rara, sendo que a pleura é o local mais acometido, e o envolvimento do retroperitônio é raro, com poucos relatos na literatura. O presente artigo expõe uma paciente com dor abdominal e massa palpável no epigástrio, com à exérese da lesão como tratamento adotado. O diagnóstico é confirmado pelo estudo anatomopatológico complementado por imuno-histoquímica, de tumor fibroso solitário sem sinais de malignidade

    Color stability, surface roughness and microhardness of composites submitted to mouthrinsing action

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    Objective: The purpose of this study was to evaluate the effect of mouth rinse solutions Lion color stability, surface roughness and microhardness of two composite resins. Material and Methods: Fifty test specimens of each composite (Filtek Z250 and Z350; 3M ESPE) were made using a teflon matrix (12x2 mm). Color, surface roughness and Knoop microhardness baseline measurements of each specimen were made and specimens (n=10) were immersed in 5 mouth rinse solutions: G1: distilled water (control), G2: Plax Classic, G3: Plax alcohol-free; G4: Periogard, and G5: Listerine. Final measurements of color, roughness and microhardness were performed and the results submitted to statistical analysis (2-way ANOVA, Bonferroni's test; p<0.05). Results: The most significant color change was observed for Z250 when immersed in Listerine (p<0.05). Z350 showed greater color change when immersed in Plax alcohol-free (p<0.05), but with no significant difference for Listerine (p>0.05). With regard to roughness, both composites showed significant changes when immersed in Listerine in comparison with Plax alcohol-free (p<0.05). Microhardness of Z350 was shown to be significantly changed when the composite was immersed in Plax alcohol-free (p<0.05). Conclusion: Composite changes depended on the material itself rather than the mouth rinse solution used
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