Escalated regeneration in sciatic nerve crush injury by the combined therapy of human amniotic fluid mesenchymal stem cells and fermented soybean extracts, Natto

Attenuation of inflammatory cell deposits and associated cytokines prevented the apoptosis of transplanted stem cells in a sciatic nerve crush injury model. Suppression of inflammatory cytokines by fermented soybean extracts (Natto) was also beneficial to nerve regeneration. In this study, the effect of Natto on transplanted human amniotic fluid mesenchymal stem cells (AFS) was evaluated. Peripheral nerve injury was induced in SD rats by crushing a sciatic nerve using a vessel clamp. Animals were categorized into four groups: Group I: no treatment; Group II: fed with Natto (16 mg/day for 7 consecutive days); Group III: AFS embedded in fibrin glue; Group IV: Combination of group II and III therapy. Transplanted AFS and Schwann cell apoptosis, inflammatory cell deposits and associated cytokines, motor function, and nerve regeneration were evaluated 7 or 28 days after injury. The deterioration of neurological function was attenuated by AFS, Natto, or the combined therapy. The combined therapy caused the most significantly beneficial effects. Administration of Natto suppressed the inflammatory responses and correlated with decreased AFS and Schwann cell apoptosis. The decreased AFS apoptosis was in line with neurological improvement such as expression of early regeneration marker of neurofilament and late markers of S-100 and decreased vacuole formation. Administration of either AFS, or Natto, or combined therapy augmented the nerve regeneration. In conclusion, administration of Natto may rescue the AFS and Schwann cells from apoptosis by suppressing the macrophage deposits, associated inflammatory cytokines, and fibrin deposits

Research of Curve Fitting Method on the Measured Settlement of Tanks

AbstractThe settlement data of oil storage tanks made of steel are measured by the measurement points located around the base of the tank wall. The measured settlement data need to be curve fitted in order to reflect the settlement distribution around the whole tank wall base. Considering about the disadvantage of measured settlement data treatment methods on tanks in current standards, an optimization method of curve fitting on the measured settlement data is presented. The Fourier series expansion is used to analyze the measured settlement data, the fitting curves and mean square error according to different order are obtained. The fitting curve with minimum mean square error is selected as the most appropriate one that reflects the actual displacement of the tank base. The optimization method of curve fitting present is applied to analyze the measured settlement data obtained from the floating roof tank and the fixed roof tank. Results show that different effects can be obtained with different order of the fitting curve. Curve fitting referring to different order is necessary to the measured settlement data in actual engineering in order to find the most appropriate one that reflects the real tank base displacement distribution

Long-distant contribution and χc1\chi_{c1} radiative decays to light vector meson

The discrepancy between the PQCD calculation and the CLEO data for $\chi_{c1}\to \gamma V$ ($V=\rho^0,\,\omega,\,\phi$) stimulates our interest in exploring extra mechanism of $\chi_{c1}$ decay. In this work, we apply an important non-perturbative QCD effect, i.e., hadronic loop mechanism, to study $\chi_{c1}\to \gamma V$ radiative decay. Our numerical result shows that the theoretical results including the hadronic loop contribution and the PQCD calculation of $\chi_{c1}\to \gamma V$ are consistent with the corresponding CLEO data of $\chi_{c1}\to \gamma V$. We expect further experimental measurement of $\chi_{c1}\to \gamma V$ at BES-III, which will be helpful to test the hadronic loop effect on $\chi_{c1}$ decay.Comment: 7 pages, 2 figures. Accepted for publication in Eur. Phys. J.

Transport spin polarization of Ni_xFe_{1-x}: electronic kinematics and band structure

We present measurements of the transport spin polarization of Ni_xFe_{1-x} (0<x<1) using the recently-developed Point Contact Andreev Reflection technique, and compare them with our first principles calculations of the spin polarization for this system. Surpisingly, the measured spin polarization is almost composition-independent. The results clearly demonstrate that the sign of the transport spin polarization does not coincide with that of the difference of the densities of states at the Fermi level. Calculations indicate that the independence of the spin polarization of the composition is due to compensation of density of states and Fermi velocity in the s- and d- bands

Development of a metal-free black phosphorus/graphitic carbon nitride heterostructure for visible-light-driven degradation of indomethacin

The development of affordable and efficient technologies for the removal of pharmaceuticals and personal care products (PPCPs) from water has recently been the subject of extensive attention. In this study, a black phosphorus/graphitic carbon nitride (BP-g-C3N4) heterostructure is fabricated as an extremely active metal-free photocatalyst via a newly-developed exfoliation strategy. The BP-g-C3N4 shows an 11 times better decomposition rate of a representative PPCPs-type pollutant, indomethacin (IDM), compared to the widely used P25 TiO2 under real-sunlight illumination. Also, its visible-light activity is even better than that of the best photocatalysts previously developed, but only consumes 1/10-1/4 of the catalyst. The results show that BP performs a cocatalyst-like behavior to catalyze the generation of reactive oxygen species, thus speeding up the decomposition of IDM. In addition, the BP-g-C3N4 photocatalyst also exhibits excellent IDM removal efficiency in authentic water matrices (tap water, surface water, and secondarily treated sewage effluent). Large-scale application demonstration under natural sunlight further reveals the practicality of BP-g-C3N4 for real-world water treatment operations. Our work will open up new possibilities in the development of purely metal-free photocatalysts for "green" environmental remediation applications. (C) 2021 Elsevier B.V. All rights reserved.Environmental Biolog

Study of the decay asymmetry parameter and CP violation parameter in the Lambdac+ --> Lambda pi+ decay

Using data from the FOCUS (E831) experiment at Fermilab, we present a new measurement of the weak decay-asymmetry parameter alpha(Lambdac) in Lambdac --> Lambda pi decay. Comparing particle with antiparticle decays, we obtain the first measurement of the CP violation parameter : A = [alpha(Lambdac)+alpha(antiLambda_c)]/[alpha(Lambdac)-alpha(antiLambda_c)]. We obtain alpha(Lambdac)=-0.78+-0.16+-0.13 and A = -0.07+-0.19+-0.12 where errors are statistical and systematic.Comment: 18 pages, to be submitted to Phys. Lett. B For a list of the FOCUS collaboration, see http://www-focus.fnal.gov/authors.htm

New way of healing : experienced counsellors’ perceptions of the influence of ch’i-related exercises on counselling practice in Taiwan

This study examines how Taiwanese senior counsellors with substantial experience of ch’i-related exercise (CRE) perceived the influence of their regular CRE on their counselling practice. I am interested in the perceived influence of CRE on both self-care and professional practice. In this studyn this studyn this study n this study n this study n this study, CRE, CRE, CRE, CRE, CRE refers to any refers to any refers to any refers to any ch'i enhancing exercise that coordinates movement with breathing and inner concentration wherein ch'i is a first order concept used by practitioners and regarded by them as an embodiment of ideas related to human life and human existence and able to be experienced and refined through any ch'i related exercise. CRE is a set of practices and an intrinsic part of local culture in Taiwan which in recent years, has become popular practice in Taiwanese society. There are growing numbers of counselling professionals involved in regular CRE in recent years. Studies examining the effects of CRE indicate the benefits of CRE on practitioners' global health and personal growth. However, no previous study has investigated the influence of the long-term regular use of CRE on counsellors‟ self-care and counselling practice. The narrative research design for this study was developed from a post-structural theoretical perspective located in the domain of social constructivism. The data were co-constructed between the researcher and 12 senior Taiwanese counsellors with substantial CRE experience using a semi-structured in-depth interview approach. Interview data were analysed using the structure-based approach developed by William Labov in the field of socio-linguistics. The study reveals an overall benefit of regular involvement in CRE for practitioners' global wellbeing and personal growth counsellor' self-care. The research findings also reveals the potential of ch’i to be used as a way of expressing health and illness and a way of understanding in therapy and CRE to be lived out in therapy as an embodiment. I argue that collectively the narratives, as a whole, give evidence of an increasing integratin of the ideas and practices of ch’i into counselling practice in contemporary Taiwan. This might even make up a new form of integrated and culturally appropriate practice, what I term "a new way of healing." These are therapeutic practices which value the potential of CRE for counsellor's self-care and personal growth; recognize the integral whole of the human person; promote conscious use of the knowledge and experience of ch’i and CRE in therapy as an important aspect of the therapeutic use of self. Implications for practice such as the potential of CRE to be introduced into counsellor training programmes for counsellors' preparation or ongoing education are provided. Recommendations for future research such as the development of a new healing modality based on the research findings are offered

BESII Detector Simulation

A Monte Carlo program based on Geant3 has been developed for BESII detector simulation. The organization of the program is outlined, and the digitization procedure for simulating the response of various sub-detectors is described. Comparisons with data show that the performance of the program is generally satisfactory.Comment: 17 pages, 14 figures, uses elsart.cls, to be submitted to NIM

In Situ Observations of the Deformation Behavior and Fracture Mechanisms of Ti-45Al-2Nb-2Mn+0.8 vol pct TiB₂

The deformation and fracture mechanisms of a nearly lamellar Ti-45Al-2Nb-2Mn (at. pct) + 0.8 vol pct TiB₂ intermetallic, processed into an actual low-pressure turbine blade, were examined by means of in situ tensile and tensile-creep experiments performed inside a scanning electron microscope (SEM). Low elongation-to-failure and brittle fracture were observed at room temperature, while the larger elongations-to-failure at high temperature facilitated the observation of the onset and propagation of damage. It was found that the dominant damage mechanisms at high temperature depended on the applied stress level. Interlamellar cracking was observed only above 390 MPa, which suggests that there is a threshold below which this mechanism is inhibited. Failure during creep tests at 250 MPa was controlled by intercolony cracking. The in situ observations demonstrated that the colony boundaries are damage nucleation and propagation sites during tensile creep, and they seem to be the weakest link in the microstructure for the tertiary creep stage. Therefore, it is proposed that interlamellar areas are critical zones for fracture at higher stresses, whereas lower stress, high-temperature creep conditions lead to intercolony cracking and fracture.The authors are grateful to Industria de Turbo Propulsores, S.A. for supplying the intermetallic blades. Funding from the Spanish Ministry of Science and Innovation through projects MAT2009-14547-C02-01 and MAT2009-14547-C02-02 is acknowledged. The Madrid Regional Government supported this project partially through the ESTRUMAT grant P2009/MAT-1585. C.J.B. acknowledges the support from Grant SAB2009-0045 from the Spanish Ministry of Education for his sabbatical stage in Madrid.Publicad