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The MIRD method of estimating absorbed dose
The estimate of absorbed radiation dose from internal emitters provides the information required to assess the radiation risk associated with the administration of radiopharmaceuticals for medical applications. The MIRD (Medical Internal Radiation Dose) system of dose calculation provides a systematic approach to combining the biologic distribution data and clearance data of radiopharmaceuticals and the physical properties of radionuclides to obtain dose estimates. This tutorial presents a review of the MIRD schema, the derivation of the equations used to calculate absorbed dose, and shows how the MIRD schema can be applied to estimate dose from radiopharmaceuticals used in nuclear medicine
Mollified hyperbolic method for coefficient identification problems
AbstractWe introduce a stable numerical method for the identification of a transmissivity coefficient in a one-dimensional parabolic equation. It is a combination of the Mollification Method and a well-known space marching implementation of the Hyperbolic Regularization procedure. The new method succesfully restores a certain type of continuity with respect to the initial condition and the boundary data. The accuracy of the algorithm is demonstrated by means of several examples where exact and perturbed data are considered
Superconductivity and hybrid soft modes in TiSe
The competition between superconductivity and other ground states of solids
is one of the challenging topics in condensed matter physics. Apart from
high-temperature superconductors [1,2] this interplay also plays a central role
in the layered transition-metal dichalcogenides, where superconductivity is
stabilized by suppressing charge-density-wave order to zero temperature by
intercalation [3] or applied pressure [4-7]. 1T-TiSe forms a prime example,
featuring superconducting domes on intercalation as well as under applied
pressure. Here, we present high energy-resolution inelastic x-ray scattering
measurements of the CDW soft phonon mode in intercalated CuTiSe and
pressurized 1T-TiSe along with detailed ab-initio calculations for the
lattice dynamical properties and phonon-mediated superconductivity. We find
that the intercalation-induced superconductivity can be explained by a solely
phonon-mediated pairing mechanism, while this is not possible for the
superconducting phase under pressure. We argue that a hybridization of phonon
and exciton modes in the pairing mechanism is necessary to explain the full
observed temperature-pressure-intercalation phase diagram. These results
indicate that 1T-TiSe under pressure is close to the elusive state of the
excitonic insulator
Gastrocnemius medialis contractile behavior during running differs between simulated Lunar and Martian gravities
The international partnership of space agencies has agreed to proceed forward to the Moon sustainably. Activities on the Lunar surface (0.16 g) will allow crewmembers to advance the
exploration skills needed when expanding human presence to Mars (0.38 g). Whilst data from actual hypogravity activities are limited to the Apollo missions, simulation studies have indicated that ground reaction forces, mechanical work, muscle activation, and joint angles decrease with declining gravity level. However, these alterations in locomotion biomechanics do not necessarily scale to the gravity level, the reduction in gastrocnemius medialis activation even appears to level off around 0.2 g, while muscle activation pattern remains similar. Thus, it is difficult to predict whether gastrocnemius medialis contractile behavior during running on Moon will basically be the same as on Mars. Therefore, this study investigated lower limb joint kinematics and gastrocnemius medialis behavior during running at 1 g, simulated Martian gravity, and simulated Lunar gravity on the vertical treadmill facility. The results indicate that hypogravity-induced alterations in joint kinematics and contractile behavior still persist between simulated running on the Moon and Mars. This contrasts
with the concept of a ceiling effect and should be carefully considered when evaluating exercise prescriptions and the transferability of locomotion practiced in Lunar gravity to Martian gravity
Contractile behavior of the gastrocnemius medialis muscle during running in simulated hypogravity
Vigorous exercise countermeasures in microgravity can largely attenuate muscular degeneration, albeit the extent of applied loading is key for the extent of muscle wasting. Running on the International Space Station is usually performed with maximum loads of 70% body weight (0.7 g). However, it has not been investigated how the reduced musculoskeletal loading affects muscle and series elastic element dynamics, and thereby force and power generation. Therefore, this study examined the effects of running on the vertical treadmill facility, a ground-based analog, at simulated 0.7 g on gastrocnemius medialis contractile behavior. The results reveal that fascicle−series elastic element behavior differs between simulated hypogravity and 1 g running. Whilst shorter peak series elastic element lengths at simulated 0.7 g appear to be the result of lower muscular and gravitational forces acting on it, increased fascicle lengths and decreased velocities could not be anticipated, but may inform the development of optimized running training in hypogravity. However, whether the alterations in contractile behavior precipitate musculoskeletal degeneration
warrants further study
Arithmetic Branching Programs with Memory
We extend the well known characterization of VPws as the class of polynomials computed by polynomial size arithmetic branching programs to other complexity classes. In order to do so we add additional memory to the computation of branching programs to make them more expressive. We show that allowing different types of memory in branching programs increases the computational power even for constant width programs. In particular, this leads to very natural and robust characterizations of VP and VNP by branching programs with memory. 1
Monte Carlo study of the critical temperature for the planar rotator model with nonmagnetic impurities
We performed Monte Carlo simulations to calculate the
Berezinskii-Kosterlitz-Thouless (BKT) temperature for the
two-dimensional planar rotator model in the presence of nonmagnetic impurity
concentration . As expected, our calculation shows that the BKT
temperature decreases as the spin vacancies increase. There is a critical
dilution at which . The effective interaction
between a vortex-antivortex pair and a static nonmagnetic impurity is studied
analytically. A simple phenomenological argument based on the pair-impurity
interaction is proposed to justify the simulations.Comment: 5 pages, 5 figures, Revetex fil
Penetration Depth Measurements in MgB_2: Evidence for Unconventional Superconductivity
We have measured the magnetic penetration depth of the recently discovered
binary superconductor MgB_2 using muon spin rotation and low field
-susceptibility. From the damping of the muon precession signal we find the
penetration depth at zero temperature is about 85nm. The low temperature
penetration depth shows a quadratic temperature dependence, indicating the
presence of nodes in the superconducting energy gap.Comment: 4 pages 3 figure
Statistical Survey of Type III Radio Bursts at Long Wavelengths Observed by the Solar TErrestrial RElations Observatory (STEREO)/Waves Instruments: Radio Flux Density Variations with Frequency
We have performed a statistical study of Type III radio bursts observed
by Solar TErrestrial RElations Observatory (STEREO)/Waves between May 2007 and
February 2013. We have investigated the flux density between kHz and
MHz. Both high- and low-frequency cutoffs have been observed in of
events suggesting an important role of propagation. As already reported by
previous authors, we observed that the maximum flux density occurs at MHz on
both spacecraft. We have developed a simplified analytical model of the flux
density as a function of radial distance and compared it to the STEREO/Waves
data.Comment: published in Solar Physic
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