4,314 research outputs found
Vectorcardiographic changes during extended space flight
To assess the effects of space flight on cardiac electrical properties, vectorcardiograms were taken on the 9 Skylab astronauts during the flights of 28, 59, and 84 days. The Frank lead system was used and observations were made at rest; during 25%, 50% and 75% of maximum exercise; during a short pulse of exercise (150 watts, 2 minutes); and after exercise. Data from 131 in-flight tests were analyzed by computer and compared to preflight and postflight values. Statistically significant increase in QRS vector magnitude (six of nine crewmen); T vector magnitude (five of nine crewmen); and resting PR interval duration (six of nine crewmen) occurred. During exercise the PR interval did not differ from preflight. Exercise heart rates inflight were the same as preflight, but increased in the immediate postflight period. With the exception of the arrhythmias, no deleterious vectorcardiographic changes were observed during the Skylab missions
Carrier dynamics and coherent acoustic phonons in nitride heterostructures
We model generation and propagation of coherent acoustic phonons in
piezoelectric InGaN/GaN multi-quantum wells embedded in a \textit{pin} diode
structure and compute the time resolved reflectivity signal in simulated
pump-probe experiments. Carriers are created in the InGaN wells by ultrafast
pumping below the GaN band gap and the dynamics of the photoexcited carriers is
treated in a Boltzmann equation framework. Coherent acoustic phonons are
generated in the quantum well via both deformation potential electron-phonon
and piezoelectric electron-phonon interaction with photogenerated carriers,
with the latter mechanism being the dominant one. Coherent longitudinal
acoustic phonons propagate into the structure at the sound speed modifying the
optical properties and giving rise to a giant oscillatory differential
reflectivity signal. We demonstrate that coherent optical control of the
differential reflectivity can be achieved using a delayed control pulse.Comment: 14 pages, 11 figure
The Physics of Miniature Worlds
This excerpt from a book length work on the history of the methodology of experimental physical models (physically similar systems) interwoven in Ludwig Wittgenstein's life begins in 1913-1914. It also discusses works by physicists around the same time that were thematically related to the philosophical topics he was working on: Ludwig Boltzmann, Wilhelm Ostwald, Edgar Buckingham, James Thomson, D'Arcy Wentworth Thompson, Henry Crew (and his new translation of Galileo's Two New Sciences during this period), Heike Kamerlingh Onnes, Van Der Waals, and Rayleigh (following up on the work of Gabriel Stokes), and Richard C Tolman. The landmark work at Britain's National Physical Laboratory in 1914 on Similar Motions by Stanton and Pannell, following up on Osborne Reynolds' work in Manchester, is also described and discussed.
Connections between physics and the history of flight are mentioned, too: Penuad's successes, Boltzmann's relationship with engineer Otto Lilienthal, and the significance that Hermann von Helmholtz's landmark paper in meteorology which addressed the problem of steering aircraft, took on during this period
The calpastatin-derived calpain inhibitor CP1B reduces mRNA expression of matrix metalloproteinase-2 and-9 and invasion by leukemic THP-1 cells
The ubiquitous proteases Ό- and m-calpain are Ca2+-dependent cysteine endopeptidases. Besides involvement in a variety of physio(patho)logical processes, recent studies suggest a pivotal role of calpains in differentiation of hematopoietic cells and tumor cell invasion. However, the precise actions of calpains and their endogenous inhibitor, calpastatin, in these processes are only partially understood. Here we have studied the role of the calpain/calpastatin system in the invasion of leukemic cells under basal and differentiationstimulating conditions. To further differentiate the human leukaemic cell line THP-1 (monocytic), the cells were treated for 24 hours with the differentiationstimulating reagents phorbol 12-myristate 13-acetate (PMA) and dimethyl sulfoxide (DMSO). Macrophage and granulocytelike differentiation was confirmed by induction of vimentin expression as well as by microscopic and fluorescence assisted cytometric analysis. Extracellular matrix (ECM) invasion of both the basal and differentiation stimulated cells in a Matrigel assay was inhibited by preincubation of the cells with the specific calpain inhibitor CP1B for 24 hours. Inhibition of invasiveness correlated with decreased mRNA expression and secretion of the matrix metalloproteinases MMP-2 and MMP-9. In contrast, addition of CP1B only during the invasion process did neither influence transmigration nor MMP release. This is the first report showing that the calpain/calpastatin system mediates MMPmRNA expression of the leukemic THP-1 cells and as a consequence their invasiveness
Propagating Coherent Acoustic Phonon Wavepackets in InMnAs/GaSb
We observe pronounced oscillations in the differential reflectivity of a
ferromagnetic InMnAs/GaSb heterostructure using two-color pump-probe
spectroscopy. Although originally thought to be associated with the
ferromagnetism, our studies show that the oscillations instead result from
changes in the position and frequency-dependent dielectric function due to the
generation of coherent acoustic phonons in the ferromagnetic InMnAs layer and
their subsequent propagation into the GaSb. Our theory accurately predicts the
experimentally measured oscillation period and decay time as a function of
probe wavelength.Comment: 4 pages, 4 figure
Generalized Involution Models for Wreath Products
We prove that if a finite group has a generalized involution model, as
defined by Bump and Ginzburg, then the wreath product also has a
generalized involution model. This extends the work of Baddeley concerning
involution models for wreath products. As an application, we construct a
Gelfand model for wreath products of the form with abelian, and
give an alternate proof of a recent result due to Adin, Postnikov, and Roichman
describing a particularly elegant Gelfand model for the wreath product \ZZ_r
\wr S_n. We conclude by discussing some notable properties of this
representation and its decomposition into irreducible constituents, proving a
conjecture of Adin, Roichman, and Postnikov's.Comment: 29 page
Review of biorthogonal coupled cluster representations for electronic excitation
Single reference coupled-cluster (CC) methods for electronic excitation are
based on a biorthogonal representation (bCC) of the (shifted) Hamiltonian in
terms of excited CC states, also referred to as correlated excited (CE) states,
and an associated set of states biorthogonal to the CE states, the latter being
essentially configuration interaction (CI) configurations. The bCC
representation generates a non-hermitian secular matrix, the eigenvalues
representing excitation energies, while the corresponding spectral intensities
are to be derived from both the left and right eigenvectors. Using the
perspective of the bCC representation, a systematic and comprehensive analysis
of the excited-state CC methods is given, extending and generalizing previous
such studies. Here, the essential topics are the truncation error
characteristics and the separability properties, the latter being crucial for
designing size-consistent approximation schemes. Based on the general order
relations for the bCC secular matrix and the (left and right) eigenvector
matrices, formulas for the perturbation-theoretical (PT) order of the
truncation errors (TEO) are derived for energies, transition moments, and
property matrix elements of arbitrary excitation classes and truncation levels.
In the analysis of the separability properties of the transition moments, the
decisive role of the so-called dual ground state is revealed. Due to the use of
CE states the bCC approach can be compared to so-called intermediate state
representation (ISR) methods based exclusively on suitably orthonormalized CE
states. As the present analysis shows, the bCC approach has decisive advantages
over the conventional CI treatment, but also distinctly weaker TEO and
separability properties in comparison with a full (and hermitian) ISR method
Resonant Coherent Phonon Spectroscopy of Single-Walled Carbon Nanotubes
Using femtosecond pump-probe spectroscopy with pulse shaping techniques, one
can generate and detect coherent phonons in chirality-specific semiconducting
single-walled carbon nanotubes. The signals are resonantly enhanced when the
pump photon energy coincides with an interband exciton resonance, and analysis
of such data provides a wealth of information on the chirality-dependence of
light absorption, phonon generation, and phonon-induced band structure
modulations. To explain our experimental results, we have developed a
microscopic theory for the generation and detection of coherent phonons in
single-walled carbon nanotubes using a tight-binding model for the electronic
states and a valence force field model for the phonons. We find that the
coherent phonon amplitudes satisfy a driven oscillator equation with the
driving term depending on photoexcited carrier density. We compared our
theoretical results with experimental results on mod 2 nanotubes and found that
our model provides satisfactory overall trends in the relative strengths of the
coherent phonon signal both within and between different mod 2 families. We
also find that the coherent phonon intensities are considerably weaker in mod 1
nanotubes in comparison with mod~2 nanotubes, which is also in excellent
agreement with experiment.Comment: 21 pages, 22 figure
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