348 research outputs found
PO-0748: Escalated-dose IMRT for prostate cancer: long-term toxicity and biochemical outcomes
The recognition of antegrade and retrograde atrial activation patterns using hybrid wavelet-neural network schemes
Fission studies with 140 MeV -Particles
Binary fission induced by 140 MeV -particles has been measured for
Ag, La, Ho and Au targets. The measured
quantities are the total kinetic energies, fragment masses, and fission cross
sections. The results are compared with other data and systematics. A minimum
of the fission probability in the vicinity is observed.Comment: 4 figures, 2 table
A common theme in extracellular fluids of beetles: extracellular superoxide dismutases crucial for balancing ROS in response to microbial challenge
Extracellular Cu/Zn superoxide dismutases (SODs) are critical for balancing the level of reactive oxygen species in the extracellular matrix of eukaryotes. In the present study we have detected constitutive SOD activity in the haemolymph and defensive secretions of different leaf beetle species. Exemplarily, we have chosen the mustard leaf beetle, Phaedon cochleariae, as representative model organism to investigate the role of extracellular SODs in antimicrobial defence. Qualitative and quantitative proteome analyses resulted in the identification of two extracellular Cu/Zn SODs in the haemolymph and one in the defensive secretions of juvenile P. cochleariae. Furthermore, quantitative expression studies indicated fat body tissue and defensive glands as the main synthesis sites of these SODs. Silencing of the two SODs revealed one of them, PcSOD3.1, as the only relevant enzyme facilitating SOD activity in haemolymph and defensive secretions in vivo. Upon challenge with the entomopathogenic fungus, Metarhizium anisopliae, PcSOD3.1-deficient larvae exhibited a significantly higher mortality compared to other SOD-silenced groups. Hence, our results serve as a basis for further research on SOD regulated host-pathogen interactions. In defensive secretions PcSOD3.1-silencing affected neither deterrent production nor activity against fungal growth. Instead, we propose another antifungal mechanism based on MRJP/yellow proteins in the defensive exudates
Diamond window for the ITER EC-H&CD upper launcher status of design, testing and qualification
Flexible CO<sub>2</sub> sensor architecture with selective nitrogen functionalities by one-step laser-induced conversion of versatile organic ink
Nitrogen-doped carbons (NC) are a class of sustainable materials for selective CO2 adsorption. We introduce a versatile concept to fabricate flexible NC-based sensor architectures for room-temperature sensing of CO2 in a one-step laser conversion of primary coatings cast from abundant precursors. By the unidirectional energy impact in conjunction with depth-dependent attenuation of the laser beam, a layered sensor heterostructure with porous transducer and active sensor layer is formed. Comprehensive microscopic and spectroscopic cross-sectional analyses confirm the preservation of a high content of imidazolic nitrogen in the sensor. The performance was optimized in terms of material morphology, chemical composition, and surface chemistry to achieve a linear relative resistive response of up to ∆R/R0 = -14.3% (10% of CO2). Thermodynamic analysis yields ΔadsH values of -35.6 kJ·mol-1 and 34.1 kJ·mol-1 for H2O and CO2, respectively. The sensor is operable even in humid environments (e.g., ∆R/R0,RH=80% = 0.53%) and shows good performance upon strong mechanical deformation
Aufbau eines Versuchsstandes für den ECH Upper Launcher in ITER - Schlussbericht zum Vorhaben 3FUS0010 (KIT Scientific Reports ; 7694)
Um Plasmainstabilitäten zu begegnen, werden in vier der oberen Ports im ITER Vakuumgefäß Electron Cyclotron Launcher installiert. Diese bestehen im Wesentlichen aus einer trapezförmigen Stahlkonstruktion, welche die Mikrowellenkomponenten (im Wesentlichen Spiegel und Wellenleiter) beherbergt. Bei der Konstruktion eines solchen Launchers müssen als wesentliche Vorgaben die mechanische Festigkeit, die ausreichende Kühlung des Systems und wirksame Abschirmung gegen Neutronen berücksichtigt werden
Results from 730 kg days of the CRESST-II Dark Matter Search
The CRESST-II cryogenic Dark Matter search, aiming at detection of WIMPs via
elastic scattering off nuclei in CaWO crystals, completed 730 kg days of
data taking in 2011. We present the data collected with eight detector modules,
each with a two-channel readout; one for a phonon signal and the other for
coincidently produced scintillation light. The former provides a precise
measure of the energy deposited by an interaction, and the ratio of
scintillation light to deposited energy can be used to discriminate different
types of interacting particles and thus to distinguish possible signal events
from the dominant backgrounds. Sixty-seven events are found in the acceptance
region where a WIMP signal in the form of low energy nuclear recoils would be
expected. We estimate background contributions to this observation from four
sources: 1) "leakage" from the e/\gamma-band 2) "leakage" from the
\alpha-particle band 3) neutrons and 4) Pb-206 recoils from Po-210 decay. Using
a maximum likelihood analysis, we find, at a high statistical significance,
that these sources alone are not sufficient to explain the data. The addition
of a signal due to scattering of relatively light WIMPs could account for this
discrepancy, and we determine the associated WIMP parameters.Comment: 17 pages, 13 figure
- …