Production of Milky Way structure by the Magellanic Clouds

Previous attempts at disturbing the galactic disk by the Magellanic Clouds relied on direct tidal forcing. However, by allowing the halo to actively respond rather than remain a rigid contributor to the rotation curve, the Clouds may produce a wake in the halo which then distorts the disk. Recent work reported here suggests that the Magellanic Clouds use this mechanism to produce disk distortions sufficient to account for both the radial location, position angle and sign of the HI warp and observed anomalies in stellar kinematics towards the galactic anticenter and LSR motion.Comment: 8 pages, uuencoded compressed PostScript, no figures, html version with figures and mpeg simulations available at http://www-astro.phast.umass.edu/Preprints/martin/martin1/lmc_online.htm

Effect of the Milky Way on Magellanic Cloud structure

A combination of analytic models and n-body simulations implies that the structural evolution of the Large Magellanic Cloud (LMC) is dominated by its dynamical interaction with the Milky Way. Although expected at some level, the scope of the involvement has significant observational consequences. First, LMC disk orbits are torqued out of the disk plane, thickening the disk and populating a spheroid. The torque results from direct forcing by the Milky Way tide and, indirectly, from the drag between the LMC disk and its halo resulting from the induced precession of the LMC disk. The latter is a newly reported mechanism that can affect all satellite interations. However, the overall torque can not isotropize the stellar orbits and their kinematics remains disk-like. Such a kinematic signature is observed for nearly all LMC populations. The extended disk distribution is predicted to increase the microlensing toward the LMC. Second, the disk's binding energy slowly decreases during this process, puffing up and priming the outer regions for subsequent tidal stripping. Because the tidally stripped debris will be spatially extended, the distribution of stripped stars is much more extended than the HI Magellanic Stream. This is consistent with upper limits to stellar densities in the gas stream and suggests a different strategy for detecting the stripped stars. And, finally, the mass loss over several LMC orbits is predicted by n-body simulation and the debris extends to tens of kiloparsecs from the tidal boundary. Although the overall space density of the stripped stars is low, possible existence of such intervening populations have been recently reported and may be detectable using 2MASS.Comment: 15 pages, color Postscript figures, uses emulateapj.sty. Also available from http://www-astro.phast.umass.edu/~weinberg/weinberg-pubs.htm

Evolution of the Small Magellanic Cloud

Based on the results of N-body simulations on the last 2.5 Gyr evolution of the Large and Small Magellanic Clouds (LMC and SMC, respectively) interacting with the Galaxy, we firstly show when and where the leading arms (LAs) of the Magellanic stream (MS) can pass through the Galactic plane after the MS formation. We secondly show collisions between the outer Galactic HI disk and the LAs of the MS can create giant HI holes and chimney-like structures in the disk about 0.2 Gyr ago. We thirdly show that a large amount of metal-poor gas is stripped from the SMC and transfered to the LMC during the tidal interaction between the Clouds and the Galaxy about 0.2 and 1.3 Gyr ago. We thus propose that this metal-poor gas can closely be associated with the origin of LMC's young and intermediate-age stars and star clusters with distinctively low-metallicities with [Fe/H] < -0.6.Comment: 4 pages, 3 figures, to appear in the proceedings of ``Galaxies in the Local Volume'', Sydney, 8 to 13 July, 200

Tidal Streams as Probes of the Galactic Potential

We explore the use of tidal streams from Galactic satellites to recover the potential of the Milky Way. Our study is motivated both by the discovery of the first lengthy stellar stream in the halo (\cite{it98}) and by the prospect of measuring proper motions of stars brighter than 20th magnitude in such a stream with an accuracy of $\sim 4\mu as/$yr, as will be possible with the Space Interferometry Mission (SIM). We assume that the heliocentric radial velocities of these stars can be determined from supporting ground-based spectroscopic surveys, and that the mass and phase-space coordinates of the Galactic satellite with which they are associated will also be known to SIM accuracy. Using results from numerical simulations as trial data sets, we find that, if we assume the correct form for the Galactic potential, we can predict the distances to the stars as a consequence of the narrow distribution of energy expected along the streams. We develop an algorithm to evaluate the accuracy of any adopted potential by requiring that the satellite and stars recombine within a Galactic lifetime when their current phase-space coordinates are integrated backwards. When applied to a four-dimensional grid of triaxial logarithmic potentials, with varying circular velocities, axis ratios and orientation of the major-axis in the disk plane, the algorithm can recover the parameters used for the Milky Way in a simulated data set to within a few percent using only 100 stars in a tidal stream.Comment: Revised version - original algorithm generalised to be applicable to any potential shape. LaTeX, 12 pages including 3 figures. To be published in ApJ Letter

Stanley's conjecture for critical ideals

Let S=K[x_1,x_2,...,x_n] be a polynomial ring in n variables over a field K. Stanley's conjecture holds for the modules I and S/I, when I is a critical monomial ideal. We calculate the Stanley depth of S/I when I is a canonical critical monomial ideal. For non critical monomial ideals we show the existence of a Stanley ideal with the same depth and Hilbert function.Comment: 5 page

The Magellanic Stream and the density of coronal gas in the Galactic halo

The properties of the Magellanic Stream constrain the density of coronal gas in the distant Galactic halo. We show that motion through ambient gas can strongly heat Stream clouds, driving mass loss and causing evaporation. If the ambient gas density is too high, then evaporation occurs on unreasonably short timescales. Since heating dominates drag, tidal stripping appears to be responsible for producing the Stream. Requiring the survival of the cloud MS IV for 500 Myr sets an upper limit on the halo gas density n_H< 10^{-5} cm^{-3} at 50 kpc, roughly a factor of 10 lower than that estimated from the drag model of Moore & Davis (1994). Implications for models of the evolution of gas in galaxy halos are discussed.Comment: 4 pages, 1 figure, in press, ApJ

Selective Hydrogenation and Transfer Hydrogenation for Post-Functional Synthesis of Trifluoromethylphenyl Diazirine Derivatives for Photoaffinity Labeling

Elucidation of protein functions on the basis of structure–activity relationships can reveal the mechanisms of homeostasis functions in life and is one of the greatest interests of scientists. In the human body, many proteins are activated and/or inactivated by ligands to maintain homeostasis. Understanding the mechanism of molecular interactions between small bioactive ligands and proteins is an important step in rational drug design and discovery. ! Photoaffinity labeling, which is one of the most familiar approaches for chemical biology analysis, was initiated using diazocarbonyl derivatives in 1962 (Singh et al., 1962). Many researchers have subsequently tried to establish alternative approaches for the direct identification of target proteins for the bioactive small ligands. These approaches are based on the affinity between the ligand and the target protein (Figure 1). Several reviews are published for the recent applications of photoaffinity labeling (Tomohiro et al., 2005; Hashimoto & Hatanaka, 2008). To archive photoaffinity labeling, researchers have to prepare photoaffinity labeling ligands. The native ligands must be modified by photoreactive compounds (photophores) by organic synthesi

Neuroimaging of serotonin transporters in post-stroke pathological crying

Pathological crying (PC) is a neuropsychiatric disorder characterized by an excessive tendency towards crying after brain damage. To elucidate the role of serotonin neurotransmission for PC, a pilot study was performed using single photon emission computed tomography with [123I]β-CIT to estimate central (midbrain/pons and thalamus/hypothalamus) serotonin transporter (SERT) densities in 15 stroke patients who did or did not have PC. SERT binding ratios in midbrain/pons were significantly lower in the PC subgroup