Causes of government construction projects failure in an emerging economy: evidence from Ghana

Purpose This study investigates the factors that cause government construction projects failure in a developing. Methodology The study used sequential data collection approach through an in-depth semi-structured interview (16 participants) and questionnaire survey (230 participants) to solicit their perceptions from project management practitioners, contractors and client (government officials) about the factors that lead to Ghanaian government construction projects. The Relative Importance Index (RII) was used to determine the relative importance of the factors identified. This was followed by Spearman rank correlation coefficient and Kendall’s coefficient of concordance to measure the degree of agreement among the participants on their perceptions. Findings Thirty-four (34) factors were identified as the main factors that lead into Ghanaian government construction projects failure. The top ten (10) most important factors that cause Ghanaian government construction projects failure are: political interferences, delays in payment, partisan politics, bureaucracy, corruption, poor supervision, lack of commitment by project leaders, poor planning, starting more projects than the government can fund, and change in government. The failure factors were grouped into four main themes and found that the most important failure factors are leadership. This is followed by management and administrative practices, resources, and external forces respectively. Research limitations/implications This study is limited to only the public sector and therefore finding may not be applicable in the private sector. Practical implications Policy makers and construction project management practitioners would be able to use findings as a guide during the implementation of government projects in order to reduce and/or avoid government construction projects failure. Originality/value Construction projects failure in developing countries is high. Accordingly, extant literature has been devoted to identifying the factors that lead to failure; however, they have mainly been discussed from generic point of view or individual case studies. Researches that focus exclusively on government construction projects in developing countries are rare despite the dynamics in which these projects are implemented. This research extends the construction project management literature by focusing on government construction projects in a developing economy; where there are weak public institutional systems coupled with partisanship politics and bad cultural orientation towards government sector work inherited from colonial rule

Modelling of Malaria Risk Areas in Ghana by using Environmental and Anthropogenic Variables – A Spatial Multi- Criteria Approach

Malaria is the leading cause of morbidity and mortality in Ghana, accounting for over three million cases and thousands of deaths annually. The risks of morbidity and mortality associated with malaria are characterized by spatial and temporal variation across the country. This research sought to use GIS and multi-criteria decision analysis to produce a predictive model of malaria using eight risk factors ranging from environmental to anthropogenic. Each of the risk factors was classified into three classes of malaria risk according to how it impacts malaria prevalence. The classified risk factors were finally overlaid through the use of weighted overlay after weights were determined from them using the Analytical Hierarchy Process (AHP). Results indicate that high risk areas are concentrated at the central as well as the west-southern parts of the country consisting mainly of the Ashanti, Brong Ahafo, Eastern, Central and the Western Regions. No area was classified as low risk while 53.51% and 46.49% were classified as medium and high risk respectively. The risk map created can serve not only as a predictive tool, but can be used to obtain a comprehensive understanding of the dynamics of malariatransmission.Keywords: Malaria, GIS, Analytical Hierarchy Process, Weighted Overla

A Spatio-Temporal Based Estimation of Sequestered Carbon in the Tarkwa Mining Area of Ghana

The vegetation in the Tarkwa Mining Area (TMA) has experienced changes as a result of population growth, urbanization, mining activities and illegal chainsaw operations and this has led to an increase in temperature over the past years. Therefore, studying its forest biomass carbon (C) stock and its spatio-temporal change is important to the sustainability of forest resources and understanding of the forest C budget in the TMA. In this study, aboveground forest biomass/carbon stock and its changes in the TMA were estimated from three nested-circular plots of horizontal radii 12.62 m, 8 m and 4 m using stratified random sampling from sixty locations in five land use/cover types as well as GIS/Remote Sensing techniques over a 21 year period. An estimated total of 1 250.93 ± 7 Mg/km2 carbon was recorded in the TMA. Carbon in different land-use/cover types ranges from 587.76 ± 4 Mg/km2 carbon in closed canopy to 270.23 ± 2 Mg/km2 carbon in shrubs/herbaceous. The TMA also experienced an average of 412.14 Gg of carbon (equivalent to 19.63 Gg carbon per year) lost between 1986 and 2007 due to the changes in the land use/cover types. The study area is however, considered a net source of carbon.Keywords: Spatio-Temporal, Carbon, Mining, Biomass, GI

Analysis of Risk Management Practices in the Oil and Gas Industry in Ghana. Case Study of Tema Oil Refinery (Tor)

Risk management refers to an interactive process consisting of steps, which when undertaken in sequence, enable continual improvement in decision making. The aim of risk management is to obtain understanding by all parties and agreement around what the risks really are and how they will be managed to improve performance, increase the value of firms and reduce financial distress .We used primary and secondary data in our analysis The study identified risks confronting Tema Oil Refinery (TOR) as instability in global oil prices, depreciation of the cedi against major currencies, health and safety, political interference, environmental pollution, brain drain, shortage of crude oil, huge debts as a result of subsidizing of petroleum products by government and default on the part of oil marketing companies to pay for products and  high operational risks .Other challenges as apathy on the part of staff to abide by safety rules was identified. TOR incorporates risk management in their strategic plan and have operations and Audit risk department but have been battling with effective implementation. Made recommendations to government and management of TOR on how to overcome the problems in implementing risk management in order to achieve the goals of the only refinery in Ghana. Keywords: Risk Management Practices, Management and industr

Pulse Pressure Relationships with Demographics and Kidney Function in Ashanti, Ghana

Introduction. Hypertension, particularly pulse pressure [PP] is a major risk factor for end-stage renal disease. However, the effect of individual components of hypertension namely PP, systolic [SBP] and diastolic blood pressure [DBP] on kidney function, in the general African population is unknown. Methods. Data were collected on 944 participants [aged 40-75 y], living in villages in the area around the city of Kumasi, Ghana, on demographics, medications, height, weight, BP and 24-hour creatinine clearance (CrCl). Results. The demographic and clinical characteristics were: age 55(11) [mean (SD)] years, females 62%, rural village-dwellers 52%, diabetes 1·5%, BMI 21(4) kg/m2, 24-hourCrCl as a measure of glomerular filtration rate (GFR) 84(23) ml/min/1.73 m2. 29% had BP >140/90 mmHg; SBP and DBP were 125/74(26/14) mmHg, PP was 51(17) mmHg. PP increased with age by 0.55(95% CI: 0.46,0.64) mmHg/year. PP was higher (53(17) v 49(15) mmHg; p < 0.001) in the semiurban participants. GFR decreased both with increasing PP [-0.19 (-0.27,-0.10 ml/min/1.73 m2/mmHg; p < 0.001] and SBP [-0.09 (-0.14,-0.03) ml/min/1.73 m2/mmHg; p < 0.001] but there was no significant relationship with DBP [-0.04 (-0.15,0.06)]. After adjusting for SBP, the relationship between GFR and PP became steeper [-0.31 (-0.50,-0.12) ml/min/1.73 m2/mmHg; p < 0.001]. Using multivariate regression analysis that included PP, age, gender, BMI, only increasing age [-0.75 (-0.88,-0.62)] and decreasing BMI [0.49 (0.16,0.81)] were associated with decreased kidney function. Conclusions. In this homogeneous West-African population, PP increased with age and had a steeper relationship with declining kidney function than SBP or DBP

Assessment of trace metal contamination by geochemical normalisation in sediments of two lagoons: A comparative study of the Kpeshie and Muni lagoons, Ghana

Heavy metal contamination status of bottom sediments of two lagoons was compared by the employment of Enrichment Factor (EF) analysis for Iron (Fe), Manganese (Mn), Cupper (Cu), Lead (Pb), Chromium (Cr), Nickel (Ni), Silver (Ag), Zinc (Zn) and Mercury (Hg). Kpeshie Lagoon recorded enrichment (EF ≥ 1) for Cd, Pb, Ag, Hg and Zn, whilst Muni Lagoon recorded enrichment for Cd, Mn, Ag, Hg and Zn as metals of anthropogenic influence. Kpeshie, situated in a highly urbanized area, has 75% spatial distribution of Pb enrichment. The assessment shows that Ag and Hg are the most enriched metals in the sediments of both Lagoons, reaching extremely severe levels. Only Mn showed statistically significant difference in mean concentration of metals for both Lagoons. Pearson correlation matrix indicated that Pb had a strong relation with Ag, Hg and Zn (r = 0.956; p &lt; 0.05) which is significant in Kpeshie. It also had a strong association with Ag and Hg but not with Zn (r = 0.240) in the Muni. The study clearly delineates Pb as a pollutant that designates the urban status of Kpeshie. Its associated metals; Ag, Hg and Zn which may be coming from a common source are from industrialized zones

Combined treatment with dipeptidyl peptidase 4 (DPP4) inhibitor sitagliptin and elemental diets reduced indomethacin-induced intestinal injury in rats via the increase of mucosal glucagon-like peptide-2 concentration.

The gut incretin glucagon-like peptide-1 (GLP-1) and the intestinotropic hormone GLP-2 are released from enteroendocrine L cells in response to ingested nutrients. Treatment with an exogenous GLP-2 analogue increases intestinal villous mass and prevents intestinal injury. Since GLP-2 is rapidly degraded by dipeptidyl peptidase 4 (DPP4), DPP4 inhibition may be an effective treatment for intestinal ulcers. We measured mRNA expression and DPP enzymatic activity in intestinal segments. Mucosal DPP activity and GLP concentrations were measured after administration of the DPP4 inhibitor sitagliptin (STG). Small intestinal ulcers were induced by indomethacin (IM) injection. STG was given before IM treatment, or orally administered after IM treatment with or without an elemental diet (ED). DPP4 mRNA expression and enzymatic activity were high in the jejunum and ileum. STG dose-dependently suppressed ileal mucosal enzyme activity. Treatment with STG prior to IM reduced small intestinal ulcer scores. Combined treatment with STG and ED accelerated intestinal ulcer healing, accompanied by increased mucosal GLP-2 concentrations. The reduction of ulcers by ED and STG was reversed by co-administration of the GLP-2 receptor antagonist. DPP4 inhibition combined with luminal nutrients, which up-regulate mucosal concentrations of GLP-2, may be an effective therapy for the treatment of small intestinal ulcers

Sulfate transporters involved in sulfate secretion in the kidney are localized in the renal proximal tubule II of the elephant fish (Callorhinchus milii)

Most vertebrates, including cartilaginous fishes, maintain their plasma SO4 (2-) concentration ([SO4 (2-)]) within a narrow range of 0.2-1 mM. As seawater has a [SO4 (2-)] about 40 times higher than that of the plasma, SO4 (2-) excretion is the major role of kidneys in marine teleost fishes. It has been suggested that cartilaginous fishes also excrete excess SO4 (2-) via the kidney. However, little is known about the underlying mechanisms for SO4 (2-) transport in cartilaginous fish, largely due to the extraordinarily elaborate four-loop configuration of the nephron, which consists of at least 10 morphologically distinguishable segments. In the present study, we determined cDNA sequences from the kidney of holocephalan elephant fish (Callorhinchus milii) that encoded solute carrier family 26 member 1 (Slc26a1) and member 6 (Slc26a6), which are SO4 (2-) transporters that are expressed in mammalian and teleost kidneys. Elephant fish Slc26a1 (cmSlc26a1) and cmSlc26a6 mRNAs were coexpressed in the proximal II (PII) segment of the nephron, which comprises the second loop in the sinus zone. Functional analyses using Xenopus oocytes and the results of immunohistochemistry revealed that cmSlc26a1 is a basolaterally located electroneutral SO4 (2-) transporter, while cmSlc26a6 is an apically located, electrogenic Cl(-)/SO4 (2-) exchanger. In addition, we found that both cmSlc26a1 and cmSlc26a6 were abundantly expressed in the kidney of embryos; SO4 (2-) was concentrated in a bladder-like structure of elephant fish embryos. Our results demonstrated that the PII segment of the nephron contributes to the secretion of excess SO4 (2-) by the kidney of elephant fish. Possible mechanisms for SO4 (2-) secretion in the PII segment are discussed

Prepared for PrEP:preferences for HIV pre-exposure prophylaxis among Chinese men who have sex with men in an online national survey

BACKGROUND: Pre-exposure prophylaxis (PrEP) is not widely available in China. Previous studies reported low awareness and inconclusive findings on the acceptability of PrEP among Chinese men who have sex with men (MSM). METHODS: We conducted a secondary analysis of an online national survey comparing preferences for oral and long-acting injectable PrEP among MSM and identifying correlates of preferences. The study did not collect detailed information about partner types that may influence negotiated safety and PrEP uptake. RESULTS: Nine-hundred and seventy-nine men from the larger sample of 1045 men responded to the PrEP survey questions. Most men (81.9%) had never heard of PrEP, but reported interest in using PrEP. More participants chose injectable PrEP (36.3%) as their preferred formulation than oral PrEP (24.6%). Men who had at least two HIV tests (adjusted OR = 1.36, 95%CI 1.04, 1.78) more commonly preferred injectable PrEP. CONCLUSION: Our findings may help inform PrEP messaging in areas where PrEP has yet to be scaled up

Health Risk Assessment of Organochlorine Pesticides Contaminations in Dairy Products from Selected Farms in Greater Accra Region-Ghana

The study was geared towards ascertaining the levels of synthetic pyrethroids and organochlorine pesticides residues in dairy products(milk, cheese and yoghurt) from selected farms in Greater Accra Region of Ghana. In all fifty (50) samples of dairy products (25 fresh cow milk, 9 cheese and 16 yoghurt) were analyzed. Detectable levels of organochlorine pesticides,OCPs(β-HCH, endrin, endosulfan, p’p’-DDT, heptachlor and methoxychlor) and Synthetic pyrethroids(permethrin, allethrin, cypermethrin, deltamethrin and cyfluthrin). Ultrasonic extraction was employed and extract clean-up was done using silica gel and analyzed using a gas chromatograph (Agilent Model 6890 Gas Chromatograph) equipped with Ni-63 electron capture detector (ECD). . Milk samples were found to be the most contaminated with respect to the OCPs and the levels ranged between 0.0001μg/ml and 0.0407μg/ml. β-HCH was the highest OCP with concentration of 0.0407μg/ml while Cyfluthrin was the highest synthetic pyrethroids recorded in yoghurt sample (0.0318μg/ml).The levels of organochlorine pesticide residues detected in all the tissues were below the accepted Maximum Residue Limits (MRL), as adopted by the WHO/FAO Codex Alimentarius Commission (2005). Keywords: dairy products, organochlorine pesticides, synthetic pyrethroid, health risk, Ghana, gas chromatograph