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Dynamic Load and Storage Integration
Modern technology combined with the desire to minimize the size and weight of a shipâs power system are leading to renewed interest in more electric or all electric ships. An important characteristic of the emerging ship power system is an increasing level of load variability, with some future pulsed loads requiring peak power in excess of the available steadyâ state power. This inevitably leads to the need for some additional energy storage beyond that inherent in the fuel. With the current and evolving technology, it appears that storage will be in the form of batteries, rotating machines, and capacitors. All of these are in use on ships today and all have enjoyed significant technological improvements over the last decade. Moreover all are expected to be further enhanced by todayâs materials research. A key benefit of storage is that, when it can be justified for a given load, it can have additional beneficial uses such as ride-through capability to restart a gas turbine if there is an unanticipated power loss; alternatively, storage can be used to stabilize the power grid when switching large loads. Knowing when to stage gas turbine utilization versus energy storage is a key subject in this paper. The clear need for storage has raised the opportunity to design a comprehensive storage system, sometimes called an energy magazine, that can combine intermittent generation as well as any or all of the other storage technologies to provide a smaller, lighter and better performing system than would individual storage solutions for each potential application.Center for Electromechanic
A computational framework to emulate the human perspective in flow cytometric data analysis
Background: In recent years, intense research efforts have focused on developing methods for automated flow cytometric data analysis. However, while designing such applications, little or no attention has been paid to the human perspective that is absolutely central to the manual gating process of identifying and characterizing cell populations. In particular, the assumption of many common techniques that cell populations could be modeled reliably with pre-specified distributions may not hold true in real-life samples, which can have populations of arbitrary shapes and considerable inter-sample variation.
<p/>Results: To address this, we developed a new framework flowScape for emulating certain key aspects of the human perspective in analyzing flow data, which we implemented in multiple steps. First, flowScape begins with creating a mathematically rigorous map of the high-dimensional flow data landscape based on dense and sparse regions defined by relative concentrations of events around modes. In the second step, these modal clusters are connected with a global hierarchical structure. This representation allows flowScape to perform ridgeline analysis for both traversing the landscape and isolating cell populations at different levels of resolution. Finally, we extended manual gating with a new capacity for constructing templates that can identify target populations in terms of their relative parameters, as opposed to the more commonly used absolute or physical parameters. This allows flowScape to apply such templates in batch mode for detecting the corresponding populations in a flexible, sample-specific manner. We also demonstrated different applications of our framework to flow data analysis and show its superiority over other analytical methods.
<p/>Conclusions: The human perspective, built on top of intuition and experience, is a very important component of flow cytometric data analysis. By emulating some of its approaches and extending these with automation and rigor, flowScape provides a flexible and robust framework for computational cytomics
Boson-fermion mappings for odd systems from supercoherent states
We extend the formalism whereby boson mappings can be derived from
generalized coherent states to boson-fermion mappings for systems with an odd
number of fermions. This is accomplished by constructing supercoherent states
in terms of both complex and Grassmann variables. In addition to a known
mapping for the full so(2+1) algebra, we also uncover some other formal
mappings, together with mappings relevant to collective subspaces.Comment: 40 pages, REVTE
Time as an operator/observable in nonrelativistic quantum mechanics
The nonrelativistic Schroedinger equation for motion of a structureless
particle in four-dimensional space-time entails a well-known expression for the
conserved four-vector field of local probability density and current that are
associated with a quantum state solution to the equation. Under the physical
assumption that each spatial, as well as the temporal, component of this
current is observable, the position in time becomes an operator and an
observable in that the weighted average value of the time of the particle's
crossing of a complete hyperplane can be simply defined: ... When the
space-time coordinates are (t,x,y,z), the paper analyzes in detail the case
that the hyperplane is of the type z=constant. Particles can cross such a
hyperplane in either direction, so it proves convenient to introduce an
indefinite metric, and correspondingly a sesquilinear inner product with
non-Hilbert space structure, for the space of quantum states on such a surface.
>... A detailed formalism for computing average crossing times on a z=constant
hyperplane, and average dwell times and delay times for a zone of interaction
between a pair of z=constant hyperplanes, is presented.Comment: 31 pages, no figures. Differs from published version by minor
corrections and additions, and two citation
Schroedinger equation for joint bidirectional motion in time
The conventional, time-dependent Schroedinger equation describes only
unidirectional time evolution of the state of a physical system, i.e., forward
or, less commonly, backward. This paper proposes a generalized quantum dynamics
for the description of joint, and interactive, forward and backward time
evolution within a physical system. [...] Three applications are studied: (1) a
formal theory of collisions in terms of perturbation theory; (2) a
relativistically invariant quantum field theory for a system that kinematically
comprises the direct sum of two quantized real scalar fields, such that one
field evolves forward and the other backward in time, and such that there is
dynamical coupling between the subfields; (3) an argument that in the latter
field theory, the dynamics predicts that in a range of values of the coupling
constants, the expectation value of the vacuum energy of the universe is forced
to be zero to high accuracy. [...]Comment: 30 pages, no figures. Related material is in quant-ph/0404012.
Differs from published version by a few added remarks on the possibility of a
large-scale-average negative energy density in spac
On the quantum analogue of Galileo's leaning tower experiment
The quantum analogue of Galileo's leaning tower experiment is revisited using
wave packets evolving under the gravitational potential. We first calculate the
position detection probabilities for particles projected upwards against
gravity around the classical turning point and also around the point of initial
projection, which exhibit mass dependence at both these points. We then compute
the mean arrival time of freely falling particles using the quantum probability
current, which also turns out to be mass dependent. The mass dependence of both
the position detection probabilities and the mean arrival time vanish in the
limit of large mass. Thus, compatibility between the weak equivalence principle
and quantum mechanics is recovered in the macroscopic limit of the latter.Comment: Latex, 12 pages, 1 figure, uses IOP style, clarifications and
references adde
Bohmian approach to spin-dependent time of arrival for particles in a uniform field and for particles passing through a barrier
It is known that Lorentz covariance fixes uniquely the current and the
associated guidance law in the trajectory interpretation of quantum mechanics
for spin-1/2 particles. In the nonrelativistic domain this implies a guidance
law for electrons which differs by an additional spin-dependent term from the
one originally proposed by de Broglie and Bohm. Although the additional term in
the guidance equation may not be detectable in the quantum measurements derived
solely from the probability density , it plays a role in the case of
arrival-time measurements. In this paper we compute the arrival time
distribution and the mean arrival time at a given location, with and without
the spin contribution, for two problems: 1) a symmetrical Gaussian packet in a
uniform field and 2) a symmetrical Gaussian packet passing through a 1D
barrier. Using the Runge-Kutta method for integration of the guidance law,
Bohmian paths of these problems are also computed
Inhibition of death receptor signals by cellular FLIP.
The widely expressed protein Fas is a member of the tumour necrosis factor receptor family which can trigger apoptosis. However, Fas surface expression does not necessarily render cells susceptible to Fas ligand-induced death signals, indicating that inhibitors of the apoptosis-signalling pathway must exist. Here we report the characterization of an inhibitor of apoptosis, designated FLIP (for FLICE-inhibitory protein), which is predominantly expressed in muscle and lymphoid tissues. The short form, FLIPs, contains two death effector domains and is structurally related to the viral FLIP inhibitors of apoptosis, whereas the long form, FLIP(L), contains in addition a caspase-like domain in which the active-centre cysteine residue is substituted by a tyrosine residue. FLIPs and FLIP(L) interact with the adaptor protein FADD and the protease FLICE, and potently inhibit apoptosis induced by all known human death receptors. FLIP(L) is expressed during the early stage of T-cell activation, but disappears when T cells become susceptible to Fas ligand-mediated apoptosis. High levels of FLIP(L) protein are also detectable in melanoma cell lines and malignant melanoma tumours. Thus FLIP may be implicated in tissue homeostasis as an important regulator of apoptosis
Strong quantum violation of the gravitational weak equivalence principle by a non-Gaussian wave-packet
The weak equivalence principle of gravity is examined at the quantum level in
two ways. First, the position detection probabilities of particles described by
a non-Gaussian wave-packet projected upwards against gravity around the
classical turning point and also around the point of initial projection are
calculated. These probabilities exhibit mass-dependence at both these points,
thereby reflecting the quantum violation of the weak equivalence principle.
Secondly, the mean arrival time of freely falling particles is calculated using
the quantum probability current, which also turns out to be mass dependent.
Such a mass-dependence is shown to be enhanced by increasing the
non-Gaussianity parameter of the wave packet, thus signifying a stronger
violation of the weak equivalence principle through a greater departure from
Gaussianity of the initial wave packet. The mass-dependence of both the
position detection probabilities and the mean arrival time vanish in the limit
of large mass. Thus, compatibility between the weak equivalence principle and
quantum mechanics is recovered in the macroscopic limit of the latter. A
selection of Bohm trajectories is exhibited to illustrate these features in the
free fall case.Comment: 11 pages, 7 figure
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