1,493 research outputs found

    Identifying factors associated with the success and failure of terrestrial insect translocations

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    Translocation is increasingly used as a management strategy to mitigate the effects of human activity on biodiversity. Based on the current literature, we summarised trends in terrestrial insect translocations and identified factors associated with success and failure. As the authors’ definitions of success and failure varied according to the individual sets of goals and objectives in each project, we adopted a standardised species-specific definition of success. We applied generalised linear models and information-theoretic model selection to identify the most important factors associated with translocation success. We found literature documenting the translocation of 74 terrestrial insect species to 134 release sites. Of the translocations motivated by conservation, 52% were considered successful, 31% were considered to have failed and 17% were undetermined. Our results indicate that the number of individuals released at a translocation site was the most important factor associated with translocation success, despite this being a relatively infrequent perceived cause of failure as reported by authors. Factors relating to weather and climate and habitat quality were the most commonly perceived causes of translocation failure by authors. Consideration of these factors by managers during the planning process may increase the chance of success in future translocation attempts of terrestrial insects

    PIN12 INFANTILE GASTROENTERITIS IN THE COMMUNITY: A COST OF ILLNESS STUDY

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    Improving HIV pre-exposure prophylaxis (PrEP) adherence and retention in care: Process evaluation and recommendation development from a nationally implemented PrEP programme

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    Introduction HIV pre-exposure prophylaxis (PrEP), in which people take HIV medication to prevent HIV acquisition, underpins global HIV transmission elimination strategies. Effective prevention needs people to adhere to PrEP and remain in care during periods of risk, but this is difficult to achieve. We undertook a process evaluation of Scotland’s PrEP programme to explore barriers and facilitators to PrEP adherence and retention in care and to systematically develop evidence-based, theoretically-informed recommendations to address them. Methods We conducted semi-structured interviews and focus groups (09/2018-07/2019) with patients who identified as gay or bisexual men and were either using PrEP, had declined the offer of PrEP, had stopped PrEP, or had been assessed as ineligible for PrEP (n = 39 of whom n = 5 (13%) identified as trans, median age 31 years and interquartile range 14 years), healthcare professionals involved in PrEP provision (n = 54 including specialist sexual health doctors and nurses of various grades, PrEP prescribing general practitioners, health promotion officers, midwifes, and a PrEP clinical secretary), and clients (n = 9) and staff (n = 15) of nongovernmental organisations with an HIV prevention remit across Scotland. We used thematic analysis to map key barriers and facilitators to priority areas that could enhance adherence and retention in care. We used implementation science analytic tools (Theoretical Domains Framework, Intervention Functions, Behaviour Change Technique Taxonomy, APEASE criteria) and expert opinion to systematically generate recommendations. Results Barriers included perceived complexity of on-demand dosing, tendency for users to stop PrEP before seeking professional support, troublesome side-effects, limited flexibility in the settings/timings/nature of review appointments, PrEP-related stigma and emerging stigmas around not using PrEP. Facilitators included flexible appointment scheduling, reminders, and processes to follow up non-attenders. Examples of the 25 recommendations include: emphasising benefits of PrEP reviews and providing appointments flexibly within individualised PrEP care; using clinic systems to remind/recall PrEP users; supporting PrEP conversations among sexual partners; clear on-demand dosing guidance; encouraging good PrEP citizenship; detailed discussion on managing side-effects and care/coping planning activities. Conclusions PrEP adherence and retention in care is challenging, reducing the effectiveness of PrEP at individual and population levels. We identify and provide solutions to where and how collaborative interventions across public health, clinical, and community practice could address these challenges

    Anatomy of a mixed bioclastic–siliciclastic regressive tidal sand ridge: Facies-based case study from the lower Pleistocene Siderno Strait, southern Italy

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    Sand ridges, a common feature of modern open shelves, reflect persistent currents and sediment availability under recent transgressive conditions. They represent the largest bedforms in the oceans and, as such, can yield information on long-term oceanographic processes. However, there is a limited number of tidal sand ridges documented from the rock record, examples of regressive tidal sand ridges are scarce and studies describing ridges in straits are even more rare. This study analyses a Gelasian succession within a structurally controlled, tide-dominated strait in the Siderno Basin, southern Italy. The strait connected two wider basins, and accumulated sediments reworked by amplified tidal (bi-directional) currents. A series of tidal sand ridges with superimposed dunes developed close to the south-eastern end of the strait, where bathymetry was deeper and flow expansion occurred. One of the best-exposed tidal sand ridges, 65 m thick, crops out along a ca 2 km long cliff. Large-scale, ESE-prograding, seaward-offlapping shingles contain sets of bioclastic–siliciclastic, coarse-grained, cross-stratified sandstones, erosionally overlying upper Pliocene shelf marls and fine-grained sandstones. Cross-strata show angular, tangential and sigmoidal foresets with compound architectures and a SSE migration, i.e. oblique to the main growth direction. Fossil content indicates open-marine conditions. The succession changes abruptly across an erosion surface to non-tidal, highly burrowed mixed siliciclastic–bioclastic fine-grained sandstones, less than 15 m thick. Documented features reflect stages of nucleation, active accretion and abandonment of an individual sand ridge, during a complete cycle of relative sea-level change. The ridge formed during a phase of normal regression, with accretion occurring during an initial highstand and the ensuing falling stage. During the lowstand the ridge was split into several minor bodies by enhanced tidal currents. The ensuing transgression draped the moribund ridge with tabular strata, whereas final highstand shelf sedimentation reworked the top of the underlying sand body with weak currents

    Climate suitability as a predictor of conservation translocation failure

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    The continuing decline and loss of biodiversity has caused an increase in the use of interventionist conservation tools such as translocation. However, many translocation attempts fail to establish viable populations, with poor release site selection often flagged as an inhibitor of success. We used species distribution models (SDMs) to predict the climate suitability of 102 release sites for amphibians, reptiles and terrestrial insects and compared suitability predictions between successful and failed attempts. We then quantified the importance of climate suitability relative to five other variables frequently considered in the literature to be important determinants of translocation success: number of release years, number of individuals released, life stage released, origin of the source population and position of the release site relative to the species’ range. We found that the probability of translocation success increased with predicted climate suitability and this effect was the strongest amongst the variables considered in our analysis, accounting for 48.3% of the variation in translocation outcome. These findings should encourage greater consideration of climate suitability when selecting release sites for conservation translocations and we advocate the use of SDMs as an effective way of doing this

    Well-nested Context Unification

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    International audienceContext unification (CU) is the famous open problem of solving context equations for trees. We distinguish a new decidable fragment of CU - well-nested CU - and present a new unification algorithm that solves well-nested context equations in non-deterministic polynomial time. We show that minimal well-nested solutions of context equations can be composed from the material present in the equation. This surprising property is highly wishful when modeling natural language ellipsis in CU

    Age of the Peach Springs Tuff, southeastern California and western Arizona

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    Sanidine separates from pumice of the early Miocene Peach Springs Tuff (PST) are concordantly dated at 18.5 {plus minus} 0.2 Ma by two isotopic techniques. The PST is the only known unit that can be correlated between isolated outcrops of Miocene strata from the central Mojave Desert of southeastern California to the western Colorado Plateau in Arizona, across five structural provinces, a distance of 350 km. Thus the age of the PST is important to structural and paleogeographic reconstructions of a large region. Biotite and sanidine separates from bulk samples of the PST from zones of welding and vapor-phase alteration have not produced consistent ages by the K-Ar method. Published ages of mineral separates from 17 localities ranged from 16.2 to 20.5 Ma. Discordant {sup 40}Ar/{sup 39}Ar incremental release spectra were obtained for one biotite and two of the sanidine separates. Ages that correspond to the last gas increments are old as 27 Ma. The {sup 40}Ar/{sup 39}Ar incremental release determinations on sanidine separated from blocks of PST pumice yield ages of 18.3 {plus minus} 0.3 and 18.6 {plus minus} 0.4 Ma. Laser fusion measurements yield a mean age of 18.51 {plus minus} 0.10. The results suggest that sanidine andmore » biotite K-Ar ages older than about 18.5 Ma are due to inherited Ar from pre-Tertiary contaminants, which likely were incorporated into the tuff during deposition. Sanidine K-Ar ages younger than 18 Ma probably indicate incomplete extraction of radiogenic {sup 40}Ar, whereas laser fusion dates of biotite and hornblende younger than 18 Ma likely are due to postdepositional alteration.« les

    Changes of plasma cGP/IGF-1 molar ratio with age is associated with cognitive status of Parkinson disease

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    Objective: Cognitive impairment is a common feature of Parkinson disease (PD), for which age is a major contributing factor. Insulin-like growth factor-1 (IGF-1) declines with age and contributes to age-related cognitive impairment in PD. Cyclic glycine-proline (cGP) is a metabolite of IGF-1 and normalizes bioavailable IGF-1. Plasma cGP/IGF-1 molar ratio that represents bioactive IGF-1 in circulation, may associate with the cognitive status in PD. Methods: We examined the association of plasma cGP/IGF-1 molar ratio with the cognitive scores or age in PD patients with normal cognition (PD-N, n = 74), mild cognitive impairment (PD-MCI, n = 71), or dementia (PD-D, n = 33), and with the cognitive scores in 23 age-matched healthy controls. Plasma concentrations of IGF-1, IGF binding protein-3, and cGP were evaluated using enzyme-linked immunosorbent assay (ELISA) and high-performance liquid chromatography-mass spectrometry (HPLC-MS), respectively. Results: The cGP/IGF-1 molar ratio was positively correlated with the age of PD-N group, negatively correlated with the age of PD-D group, and not associated with the age of PD-MCI group. Independent of age, the cGP/IGF-1 molar ratio was positively correlated with the cognitive scores of healthy controls, but not in PD groups. Conclusion: Old healthy people with a higher cGP/IGF-1 molar ratio showed better preserved cognition, possibly due to improved IGF-1 function. Increased cGP/IGF-1 molar ratio with age may contribute to cognitive retention in the PD-N group. The absence or reversal of such association with age in the PD-MCI and PD-D groups may indicate the conversion of cognitive status in PD, if confirmed through longitudinal investigations within the individuals with advancing cognitive impairment

    The propensity to bargain while on a vacation

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    This article assesses how tourists' bargaining motivations and attitudes moderate their willingness to return to Italy, where bargaining is perceived as one of the best ways to deal with sellers. A non-probability quota sampling technique was used to survey domestic tourists in Italy through an online questionnaire which encompassed 26 bargaining values and one item to measure the likelihood that the tourists would bargain at the same destination in the future. The data comprised a total of 812 observations. An order probit model and marginal effects were estimated to measure the tourists' propensity to return to Italy for bargaining purposes. The study findings indicate that tourists' propensity to return for bargaining purposes is taken with the awareness that they will not obtain what they expected; as a matter of fact, they are unlikely to care about the final result but instead engage in this behaviour to have fun.FCT - National Funding Agency for Science, Research and Technology [UID/ECO/04007/2013 CEFAGE
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