Anisotropic Electron Spin Lifetime in (In,Ga)As/GaAs (110) Quantum Wells

Anisotropic electron spin lifetimes in strained undoped (In,Ga)As/GaAs (110) quantum wells of different width and height are investigated by time-resolved Faraday rotation and time-resolved transmission and are compared to the (001)-orientation. From the suppression of spin precession, the ratio of in-plane to out-of-plane spin lifetimes is calculated. Whereas the ratio increases with In concentration in agreement with theory, a surprisingly high anisotropy of 480 is observed for the broadest quantum well, when expressed in terms of spin relaxation times.Comment: 4 pages, 4 figures, revise

Blogging in the physics classroom: A research-based approach to shaping students' attitudes towards physics

Even though there has been a tremendous amount of research done in how to help students learn physics, students are still coming away missing a crucial piece of the puzzle: why bother with physics? Students learn fundamental laws and how to calculate, but come out of a general physics course without a deep understanding of how physics has transformed the world around them. In other words, they get the "how" but not the "why". Studies have shown that students leave introductory physics courses almost universally with decreased expectations and with a more negative attitude. This paper will detail an experiment to address this problem: a course weblog or "blog" which discusses real-world applications of physics and engages students in discussion and thinking outside of class. Specifically, students' attitudes towards the value of physics and its applicability to the real-world were probed using a 26-question Likert scale survey over the course of four semesters in an introductory physics course at a comprehensive Jesuit university. We found that students who did not participate in the blog study generally exhibited a deterioration in attitude towards physics as seen previously. However, students who read, commented, and were involved with the blog maintained their initially positive attitudes towards physics. Student response to the blog was overwhelmingly positive, with students claiming that the blog made the things we studied in the classroom come alive for them and seem much more relevant.Comment: 20 pages, 6 figure

Translation of Anticancer Efficacy From Nonclinical Models to the Clinic

Mouse cancer models have provided critical insights into tumor biology; however, clinical translation of these findings has been challenging. This perspective posits that factors impacting on successful translation start with limitations in capturing human cancer pathophysiology and end with challenges in generating robust translatable preclinical end points. A comprehensive approach that considers clinically relevant mouse models with both an integrated biomarker strategy and a complementary modeling and simulation effort will strengthen the current oncology drug development paradigm

Automatic Reconstruction of Fault Networks from Seismicity Catalogs: 3D Optimal Anisotropic Dynamic Clustering

We propose a new pattern recognition method that is able to reconstruct the 3D structure of the active part of a fault network using the spatial location of earthquakes. The method is a generalization of the so-called dynamic clustering method, that originally partitions a set of datapoints into clusters, using a global minimization criterion over the spatial inertia of those clusters. The new method improves on it by taking into account the full spatial inertia tensor of each cluster, in order to partition the dataset into fault-like, anisotropic clusters. Given a catalog of seismic events, the output is the optimal set of plane segments that fits the spatial structure of the data. Each plane segment is fully characterized by its location, size and orientation. The main tunable parameter is the accuracy of the earthquake localizations, which fixes the resolution, i.e. the residual variance of the fit. The resolution determines the number of fault segments needed to describe the earthquake catalog, the better the resolution, the finer the structure of the reconstructed fault segments. The algorithm reconstructs successfully the fault segments of synthetic earthquake catalogs. Applied to the real catalog constituted of a subset of the aftershocks sequence of the 28th June 1992 Landers earthquake in Southern California, the reconstructed plane segments fully agree with faults already known on geological maps, or with blind faults that appear quite obvious on longer-term catalogs. Future improvements of the method are discussed, as well as its potential use in the multi-scale study of the inner structure of fault zones

Inelastic Dark Matter in Light of DAMA/LIBRA

Inelastic dark matter, in which WIMP-nucleus scatterings occur through a transition to an excited WIMP state ~ 100 keV above the ground state, provides a compelling explanation of the DAMA annual modulation signal. We demonstrate that the relative sensitivities of various dark matter direct detection experiments are modified such that the DAMA annual modulation signal can be reconciled with the absence of a reported signal at CDMS-Soudan, XENON10, ZEPLIN, CRESST, and KIMS for inelastic WIMPs with masses O(100 GeV). We review the status of these experiments, and make predictions for upcoming ones. In particular, we note that inelastic dark matter leads to highly suppressed signals at low energy, with most events typically occurring between 20 to 45 keV (unquenched) at xenon and iodine experiments, and generally no events at low (~ 10 keV) energies. Suppressing the background in this high energy region is essential to testing this scenario. The recent CRESST data suggest seven observed tungsten events, which is consistent with expectations from this model. If the tungsten signal persists at future CRESST runs, it would provide compelling evidence for inelastic dark matter, while its absence should exclude it.Comment: 27 pages, 17 figures, minor revision

Population inversion of a NAHS mixture adsorbed into a cylindrical pore

A cylindrical nanopore immersed in a non-additive hard sphere binary fluid is studied by means of integral equation theories and Monte Carlo simulations. It is found that at low and intermediate values of the bulk total number density the more concentrated bulk species is preferentially absorbed by the pore, as expected. However, further increments of the bulk number density lead to an abrupt population inversion in the confined fluid and an entropy driven prewetting transition at the outside wall of the pore. These phenomena are a function of the pore size, the non-additivity parameter, the bulk number density, and particles relative number fraction. We discuss our results in relation to the phase separation in the bulk.Comment: 7 pages, 8 Figure

Avaliação da fertilidade do solo e do estado nutricional da cultura do caju em assentamentos do município de Caraúbas-RN

O município de Caraúbas-RN, apesar de estar situado numa área considerada de baixa aptidão para a cultura do caju, chega a produzir mais de 100.000 kg de castanhas/ano, sendo esta atividade de grande importância social e econômica, pois está diretamente relacionada com a sobrevivência de 114 famílias instaladas em assentamentos e comunidades rurais do município. O levantamento da fertilidade do solo e dos teores foliares de nutrientes tem a finalidade de identificar a existência de deficiências ou excessos destes para direcionar as pesquisas regionais de adubação a serem programadas. Diante do exposto, o principal objetivo deste trabalho foi avaliar a fertilidade dos solos cultivados com caju e o estado nutricional da cultura em três assentamentos do município de Caraúbas, Estado do Rio Grande do Norte. Os dados foram coletados em áreas dos Assentamentos Morada Nova, Petrolina e Santa Agostinha localizados no município de Caraúbas, região Oeste do Estado do RN. Realizou-se a amostragem de solo em cada área, retirando-se 20 amostras simples por lote, nas profundidades de 0-20 e 20-40 cm, onde se determinou: teores de carbono (C), potássio (K), sódio (Na), cálcio (Ca), magnésio (Mg) e alumínio (Al) trocáveis, fósforo (P) disponível; acidez potencial (Al + H) e pH em água. A partir dessas análises calcularamse a CTC total (T) e efetiva (t), soma de bases (SB), saturação por bases (V) e por alumínio (m) e porcentagem de sódio trocável (PST). Para avaliação do estado nutricional da cultura, foram escolhidas, aleatoriamente, 10 plantas por área homogênea (lote). Foram determinados os teores de P, Ca, Mg, K e Na. Calcularam-se os seguintes parâmetros estatísticos: média, valores mínimos e máximos, e coeficiente de variação. Todas as plantas apresentaram teores de P e K muito abaixo dos considerados adequados para a cultura do caju; os teores foliares de Ca e Mg, em média, foram considerados adequados para a cultura; existe a necessidade do desenvolvimento de pesquisas na área dos assentamentos com a finalidade de desenvolver ou adaptar técnicas de manejo para a cultura, para melhorar o estado nutricional das plantas e, conseqüentemente, a produção e qualidade dos frutos produzidos nesses assentamentos

Alginate hydrogels for in vivo bone regeneration : the immune competence of the animal model matters

Biomaterials with tunable biophysical properties hold great potential for tissue engineering. The adaptive immune system plays an important role in bone regeneration. Our goal is to investigate the regeneration potential of cell-laden alginate hydrogels depending on the immune status of the animal model. Specifically, the regeneration potential of rat mesenchymal stromal cell (MSC)-laden, void-forming alginate hydrogels, with a stiffness optimized for osteogenic differentiation, is studied in 5 mm critical-sized femoral defects, in both T-cell deficient athymic RNU nude rats and immunocompetent Sprague Dawley rats. Bone volume fraction, bone mineral density and tissue mineral density are higher for athymic RNU nude rats 6 weeks post-surgery. Additionally, these animals show a significantly higher number of total cells and cells with non-lymphocyte morphology at the defect site, while the number of cells with lymphocyte-like morphology is lower. Hydrogel degradation is slower and the remaining alginate fragments are surrounded by a thicker fibrous capsule. Ossification islands originating from alginate residues suggest that encapsulated MSCs differentiate into the osteogenic lineage and initiate the mineralization process. However, this effect is insufficient to fully bridge the bone defect in both animal models. Alginate hydrogels can be used to deliver MSCs and thereby recruit endogenous cells through paracrine signaling, but additional osteogenic stimuli are needed to regenerate critical-sized segmental femoral defects

Lateralization of face processing in the human brain

Are visual face processing mechanisms the same in the left and right cerebral hemispheres? The possibility of such ‘duplicated processing’ seems puzzling in terms of neural resource usage, and we currently lack a precise characterization of the lateral differences in face processing. To address this need, we have undertaken a three-pronged approach. Using functional magnetic resonance imaging, we assessed cortical sensitivity to facial semblance, the modulatory effects of context and temporal response dynamics. Results on all three fronts revealed systematic hemispheric differences. We found that: (i) activation patterns in the left fusiform gyrus correlate with image-level face-semblance, while those in the right correlate with categorical face/non-face judgements. (ii) Context exerts significant excitatory/inhibitory influence in the left, but has limited effect on the right. (iii) Face-selectivity persists in the right even after activity on the left has returned to baseline. These results provide important clues regarding the functional architecture of face processing, suggesting that the left hemisphere is involved in processing ‘low-level’ face semblance, and perhaps is a precursor to categorical ‘deep’ analyses on the right.John Merck FundSimons FoundationJames S. McDonnell FoundationNational Eye Institute (NIH, grant number R21-EY015521