1,041 research outputs found
The automation of a stellar proper motion measuring system Annual report, 1 Jul. 1966 - 30 Jun. 1967
Design and operation of automated stellar proper motion measuring syste
Beyond Conventional Boundaries: Advancing Equity and Inclusivity in Educational Supervision
This special issue of the Journal of Educational Supervision, Cases in Critical Supervision within School Contexts, critically examines educational supervision models, highlighting their limitations in fostering equity and inclusivity. As greater attention and awareness of diverse identities and experiences becomes more common in schools there also needs to be acknowledgement of how supervision is experienced by educators and enacted by instructional supervisors. We argue for a paradigm shift towards more empathetic and diverse supervisory practices that consider the varied backgrounds and needs of students. Throughout this special issue, researchers propose innovative approaches that prioritize collaboration, understanding, and the recognition of the unique potential of every teacher, educator, and student. Empowered with a willingness and an awareness of how educational experiences can be experienced differently, researchers suggest supervisory models to transform educational environments into spaces where all students, especially those from marginalized groups, can thrive
Expression of herpes simplex virus 1 glycoprotein B by a recombinant vaccinia virus and protection of mice against lethal herpes simplex virus 1 infection.
Management of hepatocellular carcinoma from diagnosis in routine clinical practice
AIM: To assess real-world management of patients diagnosed with hepatocellular carcinoma (HCC) within an integrated delivery network.
MATERIALS & METHODS: A retrospective cohort analysis of adults newly diagnosed with HCC from January 2014 to March 2019. Overall survival and treatment journey were assessed over the entire available follow-up period per patient.
RESULTS: Of the 462 patients, 85% had â„1 treatment. The 24-month overall survival rate (95% CI) from first treatment was 77% (72-82%). Majority of Child-Pugh class A (71%) and B (60%) patients received locoregional therapy first. Half (53.6%) of the patients with liver transplantation first were Child-Pugh class C patients. Sorafenib was the predominant systemic therapy.
CONCLUSION: This integrated delivery network data analysis offers a comprehensive insight into the real-world management of HCC
Non-perturbative dynamics of hot non-Abelian gauge fields: beyond leading log approximation
Many aspects of high-temperature gauge theories, such as the electroweak
baryon number violation rate, color conductivity, and the hard gluon damping
rate, have previously been understood only at leading logarithmic order (that
is, neglecting effects suppressed only by an inverse logarithm of the gauge
coupling). We discuss how to systematically go beyond leading logarithmic order
in the analysis of physical quantities. Specifically, we extend to
next-to-leading-log order (NLLO) the simple leading-log effective theory due to
Bodeker that describes non-perturbative color physics in hot non-Abelian
plasmas. A suitable scaling analysis is used to show that no new operators
enter the effective theory at next-to-leading-log order. However, a NLLO
calculation of the color conductivity is required, and we report the resulting
value. Our NLLO result for the color conductivity can be trivially combined
with previous numerical work by G. Moore to yield a NLLO result for the hot
electroweak baryon number violation rate.Comment: 20 pages, 1 figur
Nonperturbative Light-Front QCD
In this work the determination of low-energy bound states in Quantum
Chromodynamics is recast so that it is linked to a weak-coupling problem. This
allows one to approach the solution with the same techniques which solve
Quantum Electrodynamics: namely, a combination of weak-coupling diagrams and
many-body quantum mechanics. The key to eliminating necessarily nonperturbative
effects is the use of a bare Hamiltonian in which quarks and gluons have
nonzero constituent masses rather than the zero masses of the current picture.
The use of constituent masses cuts off the growth of the running coupling
constant and makes it possible that the running coupling never leaves the
perturbative domain. For stabilization purposes an artificial potential is
added to the Hamiltonian, but with a coefficient that vanishes at the physical
value of the coupling constant. The weak-coupling approach potentially
reconciles the simplicity of the Constituent Quark Model with the complexities
of Quantum Chromodynamics. The penalty for achieving this perturbative picture
is the necessity of formulating the dynamics of QCD in light-front coordinates
and of dealing with the complexities of renormalization which such a
formulation entails. We describe the renormalization process first using a
qualitative phase space cell analysis, and we then set up a precise similarity
renormalization scheme with cutoffs on constituent momenta and exhibit
calculations to second order. We outline further computations that remain to be
carried out. There is an initial nonperturbative but nonrelativistic
calculation of the hadronic masses that determines the artificial potential,
with binding energies required to be fourth order in the coupling as in QED.
Next there is a calculation of the leading radiative corrections to these
masses, which requires our renormalization program. Then the real struggle of
finding the right extensions to perturbation theory to study the
strong-coupling behavior of bound states can begin.Comment: 56 pages (REVTEX), Report OSU-NT-94-28. (figures not included,
available via anaonymous ftp from pacific.mps.ohio-state.edu in subdirectory
pub/infolight/qcd
Lung cancer risk test trial: study design, participant baseline characteristics, bronchoscopy safety, and establishment of a biospecimen repository
BACKGROUND: The Lung Cancer Risk Test (LCRT) trial is a prospective cohort study comparing lung cancer incidence among persons with a positive or negative value for the LCRT, a 15 gene test measured in normal bronchial epithelial cells (NBEC). The purpose of this article is to describe the study design, primary endpoint, and safety; baseline characteristics of enrolled individuals; and establishment of a bio-specimen repository.
METHODS/DESIGN: Eligible participants were aged 50-90 years, current or former smokers with 20 pack-years or more cigarette smoking history, free of lung cancer, and willing to undergo bronchoscopic brush biopsy for NBEC sample collection. NBEC, peripheral blood samples, baseline CT, and medical and demographic data were collected from each subject.
DISCUSSION: Over a two-year span (2010-2012), 403 subjects were enrolled at 12 sites. At baseline 384 subjects remained in study and mean age and smoking history were 62.9 years and 50.4 pack-years respectively, with 34% current smokers. Obstructive lung disease (FEV1/FVC \u3c0.7) was present in 157 (54%). No severe adverse events were associated with bronchoscopic brushing. An NBEC and matched peripheral blood bio-specimen repository was established. The demographic composition of the enrolled group is representative of the population for which the LCRT is intended. Specifically, based on baseline population characteristics we expect lung cancer incidence in this cohort to be representative of the population eligible for low-dose Computed Tomography (LDCT) lung cancer screening. Collection of NBEC by bronchial brush biopsy/bronchoscopy was safe and well-tolerated in this population. These findings support the feasibility of testing LCRT clinical utility in this prospective study. If validated, the LCRT has the potential to significantly narrow the population of individuals requiring annual low-dose helical CT screening for early detection of lung cancer and delay the onset of screening for individuals with results indicating low lung cancer risk. For these individuals, the small risk incurred by undergoing once in a lifetime bronchoscopic sample collection for LCRT may be offset by a reduction in their CT-related risks. The LCRT biospecimen repository will enable additional studies of genetic basis for COPD and/or lung cancer risk.
TRIAL REGISTRATION: The LCRT Study, NCT 01130285, was registered with Clinicaltrials.gov on May 24, 2010
Molecular excitation in the Interstellar Medium: recent advances in collisional, radiative and chemical processes
We review the different excitation processes in the interstellar mediumComment: Accepted in Chem. Re
Competing electric and magnetic excitations in backward electron scattering from heavy deformed nuclei
Important contributions to the cross sections of
low-lying orbital excitations are found in heavy deformed nuclei, arising
from the small energy separation between the two excitations with and 1, respectively. They are studied microscopically in QRPA using
DWBA. The accompanying response is negligible at small momentum transfer
but contributes substantially to the cross sections measured at for fm ( MeV)
and leads to a very good agreement with experiment. The electric response is of
longitudinal type for but becomes almost purely
transverse for larger backward angles. The transverse response
remains comparable with the response for fm
( MeV) and even dominant for MeV. This happens even at
large backward angles , where the dominance is
limited to the lower region.Comment: RevTeX, 19 pages, 8 figures included Accepted for publication in Phys
Rev
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