77 research outputs found
PTTI applications to deep space navigation
Radio metric deep space navigation relies nearly exclusively upon coherent, two way, Doppler and ranging for all precise applications. These data types and the navigational accuracies they can produce are reviewed. The deployment of hydrogen maser frequency standards and the development of Very Long Baseline Interferometry (VLBI) systems within the Deep Space Network are used in the development of non-coherent, one way data forms that promise much greater inherent navigational accuracy. The underlying structure between each data class and clock performance is charted. VLBI observations of the natural radio sources are the planned instrument for the synchronization task. This method and a navigational scheme using differential measurements between the spacecraft and nearby quasars are described
Exploration of Parameter Spaces in a Virtual Observatory
Like every other field of intellectual endeavor, astronomy is being
revolutionised by the advances in information technology. There is an ongoing
exponential growth in the volume, quality, and complexity of astronomical data
sets, mainly through large digital sky surveys and archives. The Virtual
Observatory (VO) concept represents a scientific and technological framework
needed to cope with this data flood. Systematic exploration of the observable
parameter spaces, covered by large digital sky surveys spanning a range of
wavelengths, will be one of the primary modes of research with a VO. This is
where the truly new discoveries will be made, and new insights be gained about
the already known astronomical objects and phenomena. We review some of the
methodological challenges posed by the analysis of large and complex data sets
expected in the VO-based research. The challenges are driven both by the size
and the complexity of the data sets (billions of data vectors in parameter
spaces of tens or hundreds of dimensions), by the heterogeneity of the data and
measurement errors, including differences in basic survey parameters for the
federated data sets (e.g., in the positional accuracy and resolution,
wavelength coverage, time baseline, etc.), various selection effects, as well
as the intrinsic clustering properties (functional form, topology) of the data
distributions in the parameter spaces of observed attributes. Answering these
challenges will require substantial collaborative efforts and partnerships
between astronomers, computer scientists, and statisticians.Comment: Invited review, 10 pages, Latex file with 4 eps figures, style files
included. To appear in Proc. SPIE, v. 4477 (2001
Ranger VII Flight Path and Its Determination from Tracking Data
Flight path and tracking study of Ranger VII LUNAR prob
Exploration of Large Digital Sky Surveys
We review some of the scientific opportunities and technical challenges posed
by the exploration of the large digital sky surveys, in the context of a
Virtual Observatory (VO). The VO paradigm will profoundly change the way
observational astronomy is done. Clustering analysis techniques can be used to
discover samples of rare, unusual, or even previously unknown types of
astronomical objects and phenomena. Exploration of the previously poorly probed
portions of the observable parameter space are especially promising. We
illustrate some of the possible types of studies with examples drawn from
DPOSS; much more complex and interesting applications are forthcoming.
Development of the new tools needed for an efficient exploration of these vast
data sets requires a synergy between astronomy and information sciences, with
great potential returns for both fields.Comment: To appear in: Mining the Sky, eds. A. Banday et al., ESO Astrophysics
Symposia, Berlin: Springer Verlag, in press (2001). Latex file, 18 pages, 6
encapsulated postscript figures, style files include
The Mariner 6 and 7 flight paths and their determination from tracking data
Determination of orbit estimates for Mariner 6 and 7 space probe flight
The Pioneer Anomaly
Radio-metric Doppler tracking data received from the Pioneer 10 and 11
spacecraft from heliocentric distances of 20-70 AU has consistently indicated
the presence of a small, anomalous, blue-shifted frequency drift uniformly
changing with a rate of ~6 x 10^{-9} Hz/s. Ultimately, the drift was
interpreted as a constant sunward deceleration of each particular spacecraft at
the level of a_P = (8.74 +/- 1.33) x 10^{-10} m/s^2. This apparent violation of
the Newton's gravitational inverse-square law has become known as the Pioneer
anomaly; the nature of this anomaly remains unexplained. In this review, we
summarize the current knowledge of the physical properties of the anomaly and
the conditions that led to its detection and characterization. We review
various mechanisms proposed to explain the anomaly and discuss the current
state of efforts to determine its nature. A comprehensive new investigation of
the anomalous behavior of the two Pioneers has begun recently. The new efforts
rely on the much-extended set of radio-metric Doppler data for both spacecraft
in conjunction with the newly available complete record of their telemetry
files and a large archive of original project documentation. As the new study
is yet to report its findings, this review provides the necessary background
for the new results to appear in the near future. In particular, we provide a
significant amount of information on the design, operations and behavior of the
two Pioneers during their entire missions, including descriptions of various
data formats and techniques used for their navigation and radio-science data
analysis. As most of this information was recovered relatively recently, it was
not used in the previous studies of the Pioneer anomaly, but it is critical for
the new investigation.Comment: 165 pages, 40 figures, 16 tables; accepted for publication in Living
Reviews in Relativit
Comorbidity and Sex-Related Differences in Mortality in Oxygen-Dependent Chronic Obstructive Pulmonary Disease
Background: It is not known why survival differs between men and women in oxygen-dependent chronic obstructive pulmonary disease (COPD). The present study evaluates differences in comorbidity between men and women, and tests the hypothesis that comorbidity contributes to sex-related differences in mortality in oxygen-dependent COPD. Methods: National prospective study of patients aged 50 years or older, starting long-term oxygen therapy (LTOT) for COPD in Sweden between 1992 and 2008. Comorbidities were obtained from the Swedish Hospital Discharge Register. Sex-related differences in comorbidity were estimated using logistic regression, adjusting for age, smoking status and year of inclusion. The effect of comorbidity on overall mortality and the interaction between comorbidity and sex were evaluated using Cox regression, adjusting for age, sex, Pa O2 breathing air, FEV 1, smoking history and year of inclusion. Results: In total, 8,712 patients (55 % women) were included and 6,729 patients died during the study period. No patient was lost to follow-up. Compared with women, men had significantly more arrhythmia, cancer, ischemic heart disease and renal failure, and less hypertension, mental disorders, osteoporosis and rheumatoid arthritis (P,0.05 for all odds ratios). Comorbidity was an independent predictor of mortality, and the effect was similar for the sexes. Women had lower mortality, which remained unchanged even after adjusting for comorbidity; hazard ratio 0.73 (95 % confidence interval, 0.68–0.77; P,0.001)
Effectiveness of adjuvant occupational therapy in employees with depression: design of a randomized controlled trial
<p>Abstract</p> <p>Background</p> <p>Major depressive disorder is among the medical conditions with the highest negative impact on work outcome. However, little is known regarding evidence-based interventions targeting the improvement of work outcomes in depressed employees. In this paper, the design of a randomized controlled trial is presented in order to evaluate the effectiveness of adjuvant occupational therapy in employees with depression. This occupational intervention is based on an earlier intervention, which was designed and proven effective by our research group, and is the only intervention to date that specifically targets work outcome in depressed employees.</p> <p>Methods/Design</p> <p>In a two-arm randomized controlled trial, a total of 117 participants are randomized to either 'care as usual' or <it>' </it>care as usual' with the addition of occupational therapy. Patients included in the study are employees who are absent from work due to depression for at least 25% of their contract hours, and who have a possibility of returning to their own or a new job. The occupational intervention consists of six individual sessions, eight group sessions and a work-place visit over a 16-week period. By increasing exposure to the working environment, and by stimulating communication between employer and employee, the occupational intervention aims to enhance self-efficacy and the acquisition of more adaptive coping strategies. Assessments take place at baseline, and at 6, 12, and 18-month follow-ups. Primary outcome measure is work participation (hours of absenteeism and time until work resumption). Secondary outcome measures are work functioning, symptomatology, health-related quality of life, and neurocognitive functioning. In addition, cost-effectiveness is evaluated from a societal perspective. Finally, mechanisms of change (intermediate outcomes) and potential patient-treatment matching variables are investigated.</p> <p>Discussion</p> <p>This study hopes to provide valuable knowledge regarding an intervention to treat depression, one of the most common and debilitating diseases of our time. If our intervention is proven (cost-) effective, the personal, economic, and health benefits for both patients and employers are far-reaching.</p> <p>Trial registration number</p> <p>NTR2057</p
More Evidence that Depressive Symptoms Predict Mortality in COPD Patients: Is Type D Personality an Alternative Explanation?
The present study attempted to replicate our previous finding that depressive symptoms are a risk factor for mortality in stable chronic obstructive pulmonary disease (COPD), but in a different population with a different measure of depressive symptoms. We further investigated whether type D personality is associated with mortality in patients with COPD and whether it explains any relationship observed between depressive symptoms and mortality. In 122 COPD patients, mean age 60.8 +/- 10.3 years, 52% female, and mean forced expiratory volume in 1 s (FEV(1)) 41.1 +/- 17.6%pred, we assessed body mass index, post bronchodilator FEV(1), exercise capacity, depressive symptoms with the Hospital Anxiety and Depression Scale, and type D with the Type D Scale. In the 7 years follow-up, 48 (39%) deaths occurred. The median survival time was 5.3 years. Depressive symptoms (hazard ratio = 1.07, 95% confidence intervals = 1.00-1.14) were an independent risk factor for mortality. Type D was not associated with mortality. We can rule out type D as an explanation for the relationship between depressive symptoms and mortality observed in this sample. However, ambiguity remains as to the interpretation of the value of depressive symptoms in predicting death
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