3,700 research outputs found
Multi-Gigabit Wireless data transfer at 60 GHz
In this paper we describe the status of the first prototype of the 60 GHz
wireless Multi-gigabit data transfer topology currently under development at
University of Heidelberg using IBM 130 nm SiGe HBT BiCMOS technology. The 60
GHz band is very suitable for high data rate and short distance applications as
for example needed in the HEP experments. The wireless transceiver consist of a
transmitter and a receiver. The transmitter includes an On-Off Keying (OOK)
modulator, an Local Oscillator (LO), a Power Amplifier (PA) and a BandPass
Filter (BPF). The receiver part is composed of a BandPass- Filter (BPF), a Low
Noise Amplifier (LNA), a double balanced down-convert Gilbert mixer, a Local
Oscillator (LO), then a BPF to remove the mixer introduced noise, an
Intermediate Amplifier (IF), an On-Off Keying demodulator and a limiting
amplifier. The first prototype would be able to handle a data-rate of about 3.5
Gbps over a link distance of 1 m. The first simulations of the LNA show that a
Noise Figure (NF) of 5 dB, a power gain of 21 dB at 60 GHz with a 3 dB
bandwidth of more than 20 GHz with a power consumption 11 mW are achieved.
Simulations of the PA show an output referred compression point P1dB of 19.7 dB
at 60 GHz.Comment: Proceedings of the WIT201
Irradiation study of a fully monolithic HV-CMOS pixel sensor design in AMS 180 nm
High-Voltage Monolithic Active Pixel Sensors (HV-MAPS) based on the 180 nm
HV-CMOS process have been proposed to realize thin, fast and highly integrated
pixel sensors. The MuPix7 prototype, fabricated in the commercial AMS H18
process, features a fully integrated on-chip readout, i.e. hit-digitization,
zero suppression and data serialization. It is the first fully monolithic
HV-CMOS pixel sensor that has been tested for the use in high irradiation
environments like HL-LHC. We present results from laboratory and test beam
measurements of MuPix7 prototypes irradiated with neutrons (up to
) and protons (up to ) and compare the performance with non-irradiated
sensors. Efficiencies well above 90 % at noise rates below 200 Hz per pixel are
measured. A time resolution better than 22 ns is measured for all tested
settings and sensors, even at the highest irradiation fluences. The data
transmission at 1.25 Gbit/s and the on-chip PLL remain fully functional
Synthetic Studies toward Aziridinomitosenes and 9-Oxo-pyrrolo[1,2-a]indole Mitosanes Related to the Mitomycin and FR Heterocycles.
The aminobenzoquinone mitomycins and the dihydrobenzoxazine FR compounds are potent antitumor antibiotics. Despite structural differences, the compounds are reductively activated to analogous reactive metabolites known as leucoaziridinomitosenes. Leucoaziridinomitosenes contain two electrophilic sites at the C(1) and C(10) positions which are selectively attacked by two guanosines on complementary strands of DNA, thereby resulting in cross-link formation and cell death. Much has been learned about the complex mechanism of action of these compounds, but a better understanding of their mechanisms of action and biological origins is required in order to produce more potent and less cytotoxic synthetic analogs.
The leucoaziridinomitosene derived from the semisynthetic derivative FK317 was targeted for total syntheses. The tetracyclic core of the target was accessed via intramolecular Michael addition of a chiral lithioaziridine into a vinylogous amide. Temporary protection of a stabilizing formyl group, reduction of an enoate, and subsequent transformation of the resulting alcohol provides the free C(10) carbamate. The C(10) carbamate of the intact leucoaziridinomitosene proved to be extremely labile as it was lost under acidic, basic, and neutral conditions which were explored to remove the final aziridine protecting group. Surprisingly, in contrast to the mitomycin leucoaziridinomitosenes, C(10) heterolysis of the FR leucoaziridinomitosenes was more facile than C(1) heterolysis. Nonetheless, a fully functionalized leucoaziridinomitosene derivative of FK317 was obtained.
In order to probe the related biosynthetic pathways of mitomcyin C and FR900482, a mitosane derivative that could be a common precursor of both structural families was targeted for synthesis. Multiple strategies for tetracycle construction focused on addition of a
lithioaziridine into an appropriate electrophile. The successful strategy employed a palladium catalyzed coupling of a 3,6-diazabicyclo[3.1.0]hexan-2-one to a functionalized aryl triflate, followed by diastereoselective cyclization to the desired stereoisomer of the tetracycle via carbanion addition into an appended lactam. The top face of the tetracycle is blocked by the large aziridine protecting group, which should facilitate diastereoselective reductive cleavage of a C(9) leaving group from the bottom face of the tetracycle to form the required C(9) stereochemistry. These studies culminated in the successful synthesis of a fully functionalized 9-oxo-pyrrolo[1,2a]indole mitosane derivative of the mitomycins and FR compounds.Ph.D.ChemistryUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/64647/1/deetersu_1.pd
Interferometric Observations of the Nuclear Region of Arp220 at Submillimeter Wavelengths
We report the first submillimeter interferometric observations of an
ultraluminous infrared galaxy. We observed Arp220 in the CO J=3-2 line and
342GHz continuum with the single baseline CSO-JCMT interferometer consisting of
the Caltech Submillimeter Observatory (CSO) and the James Clerk Maxwell
Telescope (JCMT). Models were fit to the measured visibilities to constrain the
structure of the source. The morphologies of the CO J=3-2 line and 342GHz
continuum emission are similar to those seen in published maps at 230 and
110GHz. We clearly detect a binary source separated by about 1 arcsec in the
east-west direction in the 342GHz continuum. The CO J=3-2 visibility
amplitudes, however, indicate a more complicated structure, with evidence for a
compact binary at some velocities and rather more extended structure at others.
Less than 30% of the total CO J=3-2 emission is detected by the interferometer,
which implies the presence of significant quantities of extended gas. We also
obtained single-dish CO J=2-1, CO J=3-2 and HCN J=4-3 spectra. The HCN J=4-3
spectrum, unlike the CO spectra, is dominated by a single redshifted peak. The
HCN J=4-3/CO J=3-2, HCN J=4-3/HCN J=1-0 and CO J=3-2/2-1 line ratios are larger
in the redshifted (eastern) source, which suggests that the two sources may
have different physical conditions. This result might be explained by the
presence of an intense starburst that has begun to deplete or disperse the
densest gas in the western source, while the eastern source harbors undispersed
high density gas.Comment: 17 pages, 9 figures, 4 Tables. accepted by Ap
Wafer test of the LHCb Outer Tracker TDC-Chip
The OTIS-TDC is the front end readout chip for the LHCb Outer Tracker. It is designed to measure drift times with a resolution better than 1 ns. As the chip will be directly mounted to its board, the test have to be performed on the wafer itself. As the testing period for 7 000 chips was only three weeks, many test routines have been implemented on a FPGA. Each chip is subjected to detailed probe testing to ensure the full functionality as well as a good performance. Overall 47 wafer have been tested. From the chips passing the test 2 000 have been used in the Outer Tracker front end electronic
The MuPix Telescope: A Thin, high Rate Tracking Telescope
The MuPix Telescope is a particle tracking telescope, optimized for tracking
low momentum particles and high rates. It is based on the novel High-Voltage
Monolithic Active Pixel Sensors (HV-MAPS), designed for the Mu3e tracking
detector. The telescope represents a first application of the HV-MAPS
technology and also serves as test bed of the Mu3e readout chain. The telescope
consists of up to eight layers of the newest prototypes, the MuPix7 sensors,
which send data self-triggered via fast serial links to FPGAs, where the data
is time-ordered and sent to the PC. A particle hit rate of 1 MHz per layer
could be processed. Online tracking is performed with a subset of the incoming
data. The general concept of the telescope, chip architecture, readout concept
and online reconstruction are described. The performance of the sensor and of
the telescope during test beam measurements are presented.Comment: Proceedings TWEPP 2016, 8 pages, 7 figure
MuPix7 - A fast monolithic HV-CMOS pixel chip for Mu3e
The MuPix7 chip is a monolithic HV-CMOS pixel chip, thinned down to 50 \mu m.
It provides continuous self-triggered, non-shuttered readout at rates up to 30
Mhits/chip of 3x3 mm^2 active area and a pixel size of 103x80 \mu m^2. The hit
efficiency depends on the chosen working point. Settings with a power
consumption of 300 mW/cm^2 allow for a hit efficiency >99.5%. A time resolution
of 14.2 ns (Gaussian sigma) is achieved. Latest results from 2016 test beam
campaigns are shown.Comment: Proceedingsfor the PIXEL2016 conference, submitted to JINST A
dangling reference has been removed from this version, no other change
SMA CO(J=6-5) and 435 micron interferometric imaging of the nuclear region of Arp 220
We have used the Submillimeter Array (SMA) to make the first interferometric
observations (beam size ~1") of the 12CO J=6-5 line and 435 micron (690 GHz)
continuum emission toward the central region of the nearby ULIRG Arp 220. These
observations resolve the eastern and western nuclei from each other, in both
the molecular line and dust continuum emission. At 435 micron, the peak
intensity of the western nucleus is stronger than the eastern nucleus, and the
difference in peak intensities is less than at longer wavelengths. Fitting a
simple model to the dust emission observed between 1.3 mm and 435 micron
suggests that dust emissivity power law index in the western nucleus is near
unity and steeper in the eastern nucleus, about 2, and that the dust emission
is optically thick at the shorter wavelength. Comparison with single dish
measurements indicate that the interferometer observations are missing ~60% of
the dust emission, most likely from a spatially extended component to which
these observations are not sensitive. The 12CO J=6-5 line observations clearly
resolve kinematically the two nuclei. The distribution and kinematics of the
12CO J=6-5 line appear to be very similar to lower J CO lies observed at
similar resolution. Analysis of multiple 12CO line intensities indicates that
the molecular gas in both nuclei have similar excitation conditions, although
the western nucleus is warmer and denser. The excitation conditions are similar
to those found in other extreme environments, including M82, Mrk 231, and BR
1202-0725. Simultaneous lower resolution observations of the 12CO, 13CO, and
C18O J=2-1 lines show that the 13CO and C18O lines have similar intensities,
which suggests that both of these lines are optically thick, or possibly that
extreme high mass star formation has produced in an overabundance of C18O.Comment: 13 pages (emulateapj), 10 figures, Accepted for publication in Ap
SMA Imaging of CO(3-2) Line and 860 micron Continuum of Arp 220 : Tracing the Spatial Distribution of Luminosity
We used the Submillimeter Array (SMA) to image 860 micron continuum and
CO(3-2) line emission in the ultraluminous merging galaxy Arp 220, achieving a
resolution of 0.23" (80 pc) for the continuum and 0.33" (120 pc) for the line.
The CO emission peaks around the two merger nuclei with a velocity signature of
gas rotation around each nucleus, and is also detected in a kpc-size disk
encompassing the binary nucleus. The dust continuum, in contrast, is mostly
from the two nuclei. The beam-averaged brightness temperature of both line and
continuum emission exceeds 50 K at and around the nuclei, revealing the
presence of warm molecular gas and dust. The dust emission morphologically
agrees with the distribution of radio supernova features in the east nucleus,
as expected when a starburst heats the nucleus. In the brighter west nucleus,
however, the submillimeter dust emission is more compact than the supernova
distribution. The 860 micron core, after deconvolution, has a size of 50-80 pc,
consistent with recent 1.3 mm observations, and a peak brightness temperature
of (0.9-1.6)x10^2 K. Its bolometric luminosity is at least 2x10^{11} Lsun and
could be ~10^{12} Lsun depending on source structure and 860 micron opacity,
which we estimate to be of the order of tau_{860} ~ 1 (i.e., N_{H_2} ~ 10^{25}
cm^{-2}). The starbursting west nuclear disk must have in its center a dust
enshrouded AGN or a very young starburst equivalent to hundreds of super star
clusters. Further spatial mapping of bolometric luminosity through
submillimeter imaging is a promising way to identify the heavily obscured
heating sources in Arp 220 and other luminous infrared galaxies.Comment: ApJ. in press. 26 pages, 10 figure
Research Proposal for an Experiment to Search for the Decay {\mu} -> eee
We propose an experiment (Mu3e) to search for the lepton flavour violating
decay mu+ -> e+e-e+. We aim for an ultimate sensitivity of one in 10^16
mu-decays, four orders of magnitude better than previous searches. This
sensitivity is made possible by exploiting modern silicon pixel detectors
providing high spatial resolution and hodoscopes using scintillating fibres and
tiles providing precise timing information at high particle rates.Comment: Research proposal submitted to the Paul Scherrer Institute Research
Committee for Particle Physics at the Ring Cyclotron, 104 page
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