229 research outputs found

    Qinghai-like H5N1 from Domestic Cats, Northern Iraq

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    Comparing Apollo and Mars Exploration Rover (MER) Operations Paradigms for Human Exploration During NASA Desert-Rats Science Operations

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    NASA's Desert Research and Technology Studies (D-RATS) field test is one of several analog tests that NASA conducts each year to combine operations development, technology advances and science under planetary surface conditions. The D-RATS focus is testing preliminary operational concepts for extravehicular activity (EVA) systems in the field using simulated surface operations and EVA hardware and procedures. For 2010 hardware included the Space Exploration Vehicles, Habitat Demonstration Units, Tri-ATHLETE, and a suite of new geology sample collection tools, including a self-contained GeoLab glove box for conducting in-field analysis of various collected rock samples. The D-RATS activities develop technical skills and experience for the mission planners, engineers, scientists, technicians, and astronauts responsible for realizing the goals of exploring planetary surfaces

    Collagen 11a1 is Indirectly Activated by Lymphocyte Enhancer-Binding Factor 1 (Lef1) and Negatively Regulates Osteoblast Maturation

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    Alpha 1 (XI) collagen (Col11a1) is essential for normal skeletal development. Mutations in Col11a1 cause Marshall and Stickler syndromes, characterized by craniofacial abnormalities, nearsightedness and hearing abnormalities. Despite its link to human diseases, few studies have characterized the factors that control Col11a1 transcription. We previously identified Col11a1 as a differentially expressed gene in Lef1-suppressed MC3T3 preosteoblasts. Here we report that Lef1 activates the Col11a1 promoter. This activation is dependent upon the DNA binding domain of Lef1, but does not require the ß-catenin interaction domain, suggesting that it is not responsive to Wnt signals. Targeted deletion of Col11a1 with an antisense morpholino accelerated osteoblastic differentiation and mineralization in C2C12 cells, similar to what was observed in Lef1-suppressed MC3T3 cells. Moreover incubation with a purified Col11a1 N-terminal fragment, V1B, prevented alkaline phosphatase expression in MC3T3 and C2C12 cells. These results suggest that Lef1 is an activator of the Col11a1 promoter and that Col11a1 suppresses terminal osteoblast differentiation

    Types and Distribution of Bright Materials in 4 Vesta

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    A strong case can be made that Vesta is the parent asteroid of the howardite, eucrite and diogenite (HED) meteorites [1]. As such, we have over a century of detailed sample analysis experience to call upon when formulating hypotheses regarding plausible lithologic diversity on Vesta. It thus came as a surprise when Dawn s Framing Camera (FC) first revealed distinctly localized materials of exceptionally low and high albedos, often closely associated. To understand the nature and origin of these materials, and how they inform us of the geological evolution of Vesta, task forces began their study. An initial step of the scientific endeavor is to develop a descriptive, non-genetic classification of objects to use as a basis for developing hypotheses and observational campaigns. Here we present a catalog of the types of light-toned deposits and their distribution across Vesta. A companion abstract [2] discusses possible origins of bright materials and the constraints they suggest for vestan geology

    Geologic mapping of the Urvara and Yalode Quadrangles of Ceres

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    We conducted geologic mapping of the Urvara (Ac-13) and Yalode (Ac-14) Quadrangles (21–66°S, 180–360°E) of the dwarf planet Ceres utilizing morphologic, topographic, and compositional information acquired by NASA's Dawn mission. The geologic characteristics of the two large impact basins Urvara (170 km diameter) and Yalode (260 km diameter) and their surroundings were investigated using Dawn Framing Camera datasets, including Survey (415 m/pixel), HAMO (140 m/pixel), and LAMO (35 m/pixel) images and mosaics, color and color ratio images, and DTMs derived from stereo-photogrammetry. Geologic mapping demonstrates that impact cratering has dominated the geologic history of the Urvara and Yalode Quadrangles, with early cratered terrain formation followed by formation of the large basins and widespread emplacement of basin-related smooth material. Impact craters display a wide range of preservation states from nearly completely buried/degraded forms to more recent pristine craters with terraced inner walls and lobate ejecta deposits. Cross-cutting relationships and morphologic signatures show that the Urvara impact followed the Yalode impact, consistent with ages derived from crater size-frequency distributions (580 ± 40 Ma for Yalode and 550 ± 50 Ma for Urvara). Observed differences in basin materials and rim morphology suggest heterogeneities in the substrate excavated by impact. Smooth deposits that cover large areas of the quadrangles, including the basin floors, rims, and exterior zones, are interpreted to be dominated by Urvara ejecta but Yalode ejecta and localized ice-rich flow material may be minor components. Geologic mapping results and simulations of ejecta emplacement suggest that Urvara and Yalode ejecta deposits extend for large distances (more than two crater diameters from the basin centers) and may serve as important stratigraphic markers for the geologic record of Ceres

    Marquette Island: A Distinct Mafic Lithology Discovered by Opportunity

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    While rolling over the Meridiani Planum sedimentary terrane, the rover Opportunity has occasionally discovered large, > 10 cm erratics. Most of these have proven to be meteorites [1], but one - Bounce Rock - is a martian basaltic rock similar in composition to the meteorite EETA79001 lithology B [2]. Presently, Opportunity is intensively investigating an --30 cm tall rock named Marquette Island that may be a distinct type of martian mafic lithology. We report the results of its continuing investigation using the Microscopic Imager (MI); Mossbauer Spectrometer (MB) and Alpha Particle X-ray Spectrometer (APXS). A companion abstract discusses the results of Panoramic Camera (Pancam) imaging of the rock [3]

    Mapping Vesta: First Results from Dawn’s Survey Orbit

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    The geologic objectives of the Dawn Mission [1] are to derive Vesta’s shape, map the surface geology, understand the geological context and contribute to the determination of the asteroids’ origin and evolution.Geomorphology and distribution of surface features will provide evidence for impact cratering, tectonic activity, volcanism, and regolith processes. Spectral measurements of the surface will provide evidence of the compositional characteristics of geological units. Age information, as derived from crater sizefrequency distributions, provides the stratigraphic context for the structural and compositional mapping results, thus revealing the geologic history of Vesta. We present here the first results of the Dawn mission from data collected during the approach to Vesta, and its first discrete orbit phase – the Survey Orbit, which lasts 21 days after the spacecraft had established a circular polar orbit at a radius of ~3000 km with a beta angle of 10°-15°
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