4,459 research outputs found
Joint effect of physical activity and sedentary behaviour on cardiovascular risk factors in Chilean adults
Background:
To investigate the associations between combined categories of moderate-to-vigorous physical activity (MVPA) and sedentary behaviour (SB) with markers of adiposity and cardiovascular risk in adults.
Methods:
Overall, 5040 participants (mean age 46.4 years and 59.3% women) from the cross-sectional Chilean National Health Survey 2009–2010 were included in this study. MVPA and SB were measured using the Global Physical Activity questionnaire. Four categories were computed using MVPA- and SB-specific cut-offs (‘High-SB & Active’, ‘Low-SB & Active’, ‘High-SB & Inactive’ and ‘Low-SB & Inactive’).
Results:
Compared to the reference group (‘High-SB & Inactive’), those in ‘High-SB & Active’ and ‘Low-SB & Active’ were less likely to have an obese BMI (OR: 0.67 [0.54; 0.85], P = 0.0001 and 0.74 [0.59; 0.92] P = 0.0007, respectively) and less likely to have metabolic syndrome (OR: 0.63 [0.49; 0.82], P < 0.0001 and 0.72 [0.57; 0.91], P = 0.007), central obesity (OR: 0.79 [0.65; 0.96], P = 0.016 and 0.71 [0.59; 0.84], P < 0.0001), diabetes (OR: 0.45 [0.35; 0.59], P < 0.0001 and 0.44 [0.34; 0.56], P < 0.0001) and hypertension (OR: 0.52 [0.43; 0.63], P < 0.0001 and 0.60 [0.50; 0.72], P < 0.0001), respectively.
Conclusions:
Being physically active and spending less time in SBs was associated with lower adiposity and improvements in cardiovascular risk factors
Klebsiella pneumoniae is able to trigger epithelial-mesenchymal transition process in cultured airway epithelial cells
The ability of some bacterial pathogens to activate Epithelial-Mesenchymal Transition normally is a consequence of the persistence of a local chronic inflammatory response or depends on a direct interaction of the pathogens with the host epithelial cells. In this study we monitored the abilities of the K. pneumoniae to activate the expression of genes related to EMT-like processes and the occurrence of phenotypic changes in airway epithelial cells during the early steps of cell infection. We describe changes in the production of intracellular reactive oxygen species and increased HIF-1α mRNA expression in cells exposed to K. pneumoniae infection. We also describe the upregulation of a set of transcription factors implicated in the EMT processes, such as Twist, Snail and ZEB, indicating that the morphological changes of epithelial cells already appreciable after few hours from the K. pneumoniae infection are tightly regulated by the activation of transcriptional pathways, driving epithelial cells to EMT. These effects appear to be effectively counteracted by resveratrol, an antioxidant that is able to exert a sustained scavenging of the intracellular ROS. This is the first report indicating that strains of K. pneumoniae may promote EMT-like programs through direct interaction with epithelial cells without the involvement of inflammatory cells
Social presence and dishonesty in retail
Self-service checkouts (SCOs) in retail can benefit consumers and retailers, providing control and autonomy to shoppers independent from staff, together with reduced queuing times. Recent research indicates that the absence of staff may provide the opportunity for consumers to behave dishonestly, consistent with a perceived lack of social presence. This study examined whether a social presence in the form of various instantiations of embodied, visual, humanlike SCO interface agents had an effect on opportunistic behaviour. Using a simulated SCO scenario, participants experienced various dilemmas in which they could financially benefit themselves undeservedly. We hypothesised that a humanlike social presence integrated within the checkout screen would receive more attention and result in fewer instances of dishonesty compared to a less humanlike agent. This was partially supported by the results. The findings contribute to the theoretical framework in social presence research. We concluded that companies adopting self-service technology may consider the implementation of social presence in technology applications to support ethical consumer behaviour, but that more research is required to explore the mixed findings in the current study.<br/
Highly Diastereo- and Enantioselective Allylboration of Aldehydes using alpha-Substituted Allyl/Crotyl Pinacol Boronic Esters via in Situ Generated Borinic Esters
Azimuthal Angle Correlations for Rapidity Separated Hadron Pairs in d+Au Collisions at sqrt(s_NN) = 200 GeV
We report on two-particle azimuthal angle correlations between charged
hadrons at forward/backward (deuteron/gold going direction) rapidity and
charged hadrons at mid-rapidity in deuteron-gold (d+Au) and proton-proton (p+p)
collisions at sqrt(s_NN) = 200 GeV. Jet structures are observed in the
correlations which we quantify in terms of the conditional yield and angular
width of away side partners. The kinematic region studied here samples partons
in the gold nucleus carrying nucleon momentum fraction x~0.1 to x~0.01. Within
this range, we find no x dependence of the jet structure in d+Au collisions.Comment: 330 authors, 6 pages text, 4 figures, no tables. Submitted to Phys.
Rev. Lett. Plain text data tables for the points plotted in figures for this
and previous PHENIX publications are (or will be) publicly available at
http://www.phenix.bnl.gov/papers.htm
Centrality dependence of charged hadron production in deuteron+gold and nucleon+gold collisions at sqrt(s_NN)=200 GeV
We present transverse momentum (p_T) spectra of charged hadrons measured in
deuteron-gold and nucleon-gold collisions at \sqrts = 200 GeV for four
centrality classes. Nucleon-gold collisions were selected by tagging events in
which a spectator nucleon was observed in one of two forward rapidity
detectors. The spectra and yields were investigated as a function of the number
of binary nucleon-nucleon collisions, \nu, suffered by deuteron nucleons. A
comparison of charged particle yields to those in p+p collisions show that the
yield per nucleon-nucleon collision saturates with \nu for high momentum
particles. We also present the charged hadron to neutral pion ratios as a
function of p_T.Comment: 330 authors, 15 pages text, 16 figures, 3 tables. Submitted to Phys.
Rev. Lett. v2 has minor changes to reflect revisions during review process.
Plain text data tables for the points plotted in figures for this and
previous PHENIX publications are (or will be) publicly available at
http://www.phenix.bnl.gov/papers.htm
Jet Structure from Dihadron Correlations in d+Au collisions at sqrt(s_NN) = 200 GeV
Dihadron correlations at high transverse momentum in d+Au collisions at
sqrt(s_NN) = 200 GeV at midrapidity are measured by the PHENIX experiment at
the Relativistic Heavy Ion Collider (RHIC). From these correlations we extract
several structural characteristics of jets; the root-mean-squared (RMS)
transverse momentum of fragmenting hadrons with respect to the jet
sqrt(), the mean sine-squared angle between the scattered partons
, and the number of particles produced within the dijet that are
associated with a high-p_T particle (dN/dx_E distributions). We observe that
the fragmentation characteristics of jets in d+Au collisions are very similar
to those in p+p collisions and that there is also little dependence on the
centrality of the d+Au collision. This is consistent with the nuclear medium
having little influence on the fragmentation process. Furthermore, there is no
statistically significant increase in the value of from p+p to
d+Au collisions. This constrains the amount of multiple scattering that partons
undergo in the cold nuclear medium before and after a hard-collision.Comment: 330 authors, 30 pages text, RevTeX4, 42 figures, 20 tables. Submitted
to Physical Review C. Plain text data tables for the points plotted in
figures for this and previous PHENIX publications are (or will be) publicly
available at http://www.phenix.bnl.gov/papers.htm
Charged hadron multiplicity fluctuations in Au+Au and Cu+Cu collisions from sqrt(s_NN) = 22.5 to 200 GeV
A comprehensive survey of event-by-event fluctuations of charged hadron
multiplicity in relativistic heavy ions is presented. The survey covers Au+Au
collisions at sqrt(s_NN) = 62.4 and 200 GeV, and Cu+Cu collisions sqrt(s_NN) =
22.5, 62.4, and 200 GeV. Fluctuations are measured as a function of collision
centrality, transverse momentum range, and charge sign. After correcting for
non-dynamical fluctuations due to fluctuations in the collision geometry within
a centrality bin, the remaining dynamical fluctuations expressed as the
variance normalized by the mean tend to decrease with increasing centrality.
The dynamical fluctuations are consistent with or below the expectation from a
superposition of participant nucleon-nucleon collisions based upon p+p data,
indicating that this dataset does not exhibit evidence of critical behavior in
terms of the compressibility of the system. An analysis of Negative Binomial
Distribution fits to the multiplicity distributions demonstrates that the heavy
ion data exhibit weak clustering properties.Comment: 464 authors from 60 institutions, 17 pages, 12 figures, 1 table.
Submitted to Physical Review C. Plain text data tables for the points plotted
in figures for this and previous PHENIX publications are (or will be)
publicly available at http://www.phenix.bnl.gov/papers.htm
High transverse momentum eta meson production in p+p, d+Au and Au+Au collisions at sqrt(s_NN) = 200 GeV
Inclusive transverse momentum spectra of eta mesons in the range p_T~2-12
GeV/c have been measured at mid-rapidity (|\eta| < 0,35) by the PHENIX
experiment at RHIC in p+p, d+Au and Au+Au collisions at sqrt(s_NN) = 200 GeV.
The eta mesons are reconstructed through their eta--> \gamma\gamma channel for
the three colliding systems as well as through the eta-->pi^0 pi+ pi- decay
mode in p+p and d+Au collisions. The nuclear modification factor in d+Au
collisions, R_dAu(p_T~1.0-1.1, suggests at most only modest p_T broadening
("Cronin enhancement"). In central Au+Au reactions, the eta yields are
significantly suppressed, with R_AuAu(pT)~0.2. The ratio of eta to pi^0 yields
is approximately constant as a function of p_T for the three colliding systems
in agreement with the high-p_T world average of R_eta/pi^0 \approx 0.5 in
hadron-hadron, hadron-nucleus, and nucleus-nucleus collisions for a wide range
of center-of-mass energies [sqrt(s_NN)~3-1800 GeV] as well as, for high scaled
momentum x_p, in e+e- annihilations at sqrt(s)=91.2 GeV. These results are
consistent with a scenario where high-p_T eta production in nuclear collisions
at RHIC is largely unaffected by initial-state effects, but where light-quark
mesons (pi^0;eta) are equally suppressed due to final-state interactions of the
parent partons in the dense medium produced in Au+Au reactions.Comment: 391 authors, NN pages text, RevTeX4, figures, tables. Submitted to
Physical Review C. Plain text data tables for the points plotted in figures
for this and previous PHENIX publications are (or will be) publicly available
at http://www.phenix.bnl.gov/papers.htm
Cold Nuclear Matter Effects on J/Psi as Constrained by Deuteron-Gold Measurements at sqrt(s_NN) = 200 GeV
We present a new analysis of J/psi production yields in deuteron-gold
collisions at sqrt(s_NN) = 200 GeV using data taken by the PHENIX experiment in
2003 and previously published in [S.S. Adler et al., Phys. Rev. Lett 96, 012304
(2006)]. The high statistics proton-proton J/psi data taken in 2005 is used to
improve the baseline measurement and thus construct updated cold nuclear matter
modification factors R_dAu. A suppression of J/psi in cold nuclear matter is
observed as one goes forward in rapidity (in the deuteron-going direction),
corresponding to a region more sensitive to initial state low-x gluons in the
gold nucleus. The measured nuclear modification factors are compared to
theoretical calculations of nuclear shadowing to which a J/psi (or precursor)
break-up cross-section is added. Breakup cross sections of sigma_breakup =
2.8^[+1.7_-1.4] (2.2^[+1.6_-1.5]) mb are obtained by fitting these calculations
to the data using two different models of nuclear shadowing. These breakup
cross section values are consistent within large uncertainties with the 4.2 +/-
0.5 mb determined at lower collision energies. Projecting this range of cold
nuclear matter effects to copper-copper and gold-gold collisions reveals that
the current constraints are not sufficient to firmly quantify the additional
hot nuclear matter effect.Comment: 453 authors from 59 institutions, 15 pages, 13 figures, 5 tables.
Submitted to Physical Review C. Plain text data tables for the points plotted
in figures for this and previous PHENIX publications are (or will be)
publicly available at http://www.phenix.bnl.gov/papers.htm
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