Случай оперативного лечения язвенной болезни двенадцатипёрстной кишки с перфорацией в брюшной отдел аорты

Случай оперативного лечения язвенной болезнидвенадцатипёрстной кишки с перфорацией в брюшной отдел аорт

Dynamics of auger working body of a multifunctional conveyor

A mathematical model of bending oscillations of a multifunctional conveyor working body with consideration of the angular velocity of its rotation and the motion along its outdoor medium is developed. Based on this model, the analytical relations were defined that describe the laws of changing the defining parameters of the working body oscillations for both non - resonant and resonant cases. The amplitude of the transition through the resonance is found to depend greatly on the relative quantity of medium motion and the rate of transition through the resonance

YbPd2In : A promising candidate for strong entropy accumulation at very low temperature

We report on synthesis, crystal structure, magnetic, thermodynamic, and transport properties of the compound YbPd2In, crystallizing as a Heusler structure type. A trivalent state of the rare earth was determined by fitting the magnetic susceptibility with a Curie-Weiss law. This compound is characterized by showing very weak magnetic interactions and a negligible Kondo effect. A specific-heat jump was observed at T 48250mK, followed at higher temperature by a power-law decrease of CP(T)/T. The resulting large electronic entropy increase at very low temperature is rapidly shifted to higher temperature by the application of magnetic field. This magnetocaloric effect places YbPd2In as a very good candidate for adiabatic demagnetization cooling processes

Breaking the superfluid speed limit in a fermionic condensate

Coherent condensates appear as emergent phenomena in many systems. They share the characteristic feature of an energy gap separating the lowest excitations from the condensate ground state. This implies that a scattering object, moving through the system with high enough velocity for the excitation spectrum in the scatterer frame to become gapless, can create excitations at no energy cost, initiating the breakdown of the condensate—the well-known Landau velocity. Whereas, for the neutral fermionic superfluid 3He-B in the T = 0 limit, flow around an oscillating body displays a very clear critical velocity for the onset of dissipation, here we show that for uniform linear motion there is no discontinuity whatsoever in the dissipation as the Landau critical velocity is passed and exceeded. Given the importance of the Landau velocity for our understanding of superfluidity, this result is unexpected, with implications for dissipative effects of moving objects in all coherent condensate systems

The use of microbubbles to target drug delivery

Ultrasound-mediated microbubbles destruction has been proposed as an innovative method for noninvasive delivering of drugs and genes to different tissues. Microbubbles are used to carry a drug or gene until a specific area of interest is reached, and then ultrasound is used to burst the microbubbles, causing site-specific delivery of the bioactive materials. Furthermore, the ability of albumin-coated microbubbles to adhere to vascular regions with glycocalix damage or endothelial dysfunction is another possible mechanism to deliver drugs even in the absence of ultrasound. This review focuses on the characteristics of microbubbles that give them therapeutic properties and some important aspects of ultrasound parameters that are known to influence microbubble-mediated drug delivery. In addition, current studies involving this novel therapeutical application of microbubbles will be discussed

Coronary microvascular resistance: methods for its quantification in humans

Coronary microvascular dysfunction is a topic that has recently gained considerable interest in the medical community owing to the growing awareness that microvascular dysfunction occurs in a number of myocardial disease states and has important prognostic implications. With this growing awareness, comes the desire to accurately assess the functional capacity of the coronary microcirculation for diagnostic purposes as well as to monitor the effects of therapeutic interventions that are targeted at reversing the extent of coronary microvascular dysfunction. Measurements of coronary microvascular resistance play a pivotal role in achieving that goal and several invasive and noninvasive methods have been developed for its quantification. This review is intended to provide an update pertaining to the methodology of these different imaging techniques, including the discussion of their strengths and weaknesses

The State of Oral Mucosa in Patients with Type 2 Diabetes

Aspects of the relationship between somatic and dental diseases are multifaceted. The bi-directional, mutually aggravating nature of the relationship between somatic and dental pathology is exemplified by diabetes mellitus. Numerous studies indicate that uncontrolled diabetes contributes to a multiple increase in the risk of caries and tooth loss, damage to the salivary glands, periodontium and oral mucosa. Given that diabetes affects all the main components of the etiology and pathogenesis of dental diseases, the urgent task of dentistry is to develop adequate methods for the treatment and prevention of dental pathology due to the presence of diabetes in the patient, which cannot be done without assessing the dental status of patients in this category. The purpose of the study was a comparative assessment of the state of oral tissues in patients with type 2 diabetes and in people of the similar age without somatic pathology. We examined 70 patients aged 34-48 years, of which 35 patients with type 2 diabetes and 35 healthy individuals of the similar age. Recruitment of patients with diabetes was carried out on the basis of the Communal non-profit enterprise "Odessa Regional Endocrinological Dispensary." All patients were clinically and radiologically examined. It was shown that the prevalence and intensity of the carious process in people with diabetes did not differ from the control group, however, the “M” component prevailed in the structure of the DMF index, the need for prosthetics was 79.1%. Hygiene was by 21.8% worse. All patients with diabetes were diagnosed with generalized periodontitis with the prevalence of an exacerbated course (25.7% more) and a direct dependence of the severity of periodontitis from the degree of decompensation of diabetes. Periodontal indices in patients with diabetes were increased: PMA index – by 70.6%, bleeding index – by 2 times, Russell index – by 1.9 times. In 63.6% of patients with diabetes, changes in the oral mucosa were noted. 25.7% of patients noted the development of candidal stomatitis / glossitis in the past. The functional activity of the salivary glands was reduced by 38.1%. Micro­crystallization of saliva in patients with diabetes is represented mainly by IV and V classes according to Leus-Kukina, which indicates its reduced mineralizing ability and the maximum risk of tooth decay