MRI role in the periprosthetic lymphoma screening: a case report

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Genomic changes of chromosomes 8p23.1 and 1q21: Novel mutations in malignant mesothelioma

Introduction: Malignant mesothelioma is an aggressive malignancy of the thoracic cavity caused by prior asbestos exposure. In the peritoneum the mesothelioma is an extremely rare condition. In the present preliminary study, high-resolution array-comparative genomic hybridization (a-CGH) was performed to identify genetic imbalances in a series of malignant peritoneal mesothelioma cases. Materials and methods: Between 1990 and 2008, among the cases recorded in the Apulia Mesothelioma Register, we found 22 peritoneal mesothelioma cases. CGH-array was performed on samples from all patients. Results: The CGH-array analysis revealed multiple chromosomal imbalances. Interestingly, deletion at 8p23.1 was observed in 12 cases. Furthermore, another novel deletion at 1q21 was present in 11. Often, 1q21 and 8p23.1 losses were present in the same patient (7 cases). Losses of BAP1 and CDKN2A loci were not detected. Discussion: The region at 8p23.1 contains the beta-defensin gene cluster (DEF) and 1q21 contains ubiquitin conjugating enzyme E2 (UBE2Q1). We hypotesized that the loss of function of ubiquitination, as well as of the defensins, could play an important role in the initial development and subsequent progression of mesothelioma

Análisis de experiencias y articulaciones agroecológicas en el corazón de una provincia fumigada

En el proyecto analizamos, desde la perspectiva de la agroecología política, las prácticas, discursos y relaciones desplegadas por dos experiencias agroecológicas de Entre Ríos e indagamos, a partir de allí, las redes y articulaciones territoriales construidas a escala provincial y nacional. Particularmente, trabajamos con los establecimientos a) “Minhoca” de la localidad de Tabossi (departamento Paraná), dedicado a la producción de cereales, oleaginosas y molienda para hacer harinas y a la cría de ganado vacuno y ovino, b) “La Dorita”, de la localidad de Basavilbaso (departamento Uruguay), que combina producción hortícola y apícola con elaboración de panificados y conservas. Privilegiamos un tipo de investigación colaborativa (Rappaport, 2007; Leyva y Speed, 2008), partiendo de instancias más o menos sistemáticas de discusión, intercambio y reflexión conjunta, intentado que los ejes de investigación se articulen con problemas derivados de la experiencia de hacer agroecología. A partir de estos intercambios surgieron algunas cuestiones que abordamos desde el proyecto: a) Un crecimiento sostenido de las experiencias agroecológicas en la provincia. b) La existencia de redes y vínculos que permiten intercambios y organización entre las mismas. c) La necesidad de contar con datos que permitan mostrar esas experiencias y redes, ya sea para potenciar sus vínculos como para gestionar recursos frente al Estado. En función de ello, se construyó colectivamente un formulario de relevamiento y se aplicó el mismo entre finales de 2022 y principios de 2023. Sus resultados parciales son presentados en la presente reseña

The effects of equine-assisted activities on the social functioning in children and adolescents with autism spectrum disorder

Equine-assisted activities and therapies are increasing in popularity for treatment of ASD symptoms. This research evaluated effects of a 5-week programme of therapeutic riding on social functioning of children/adolescents (N = 15) with ASD. The effectiveness of the programme was evaluated using the autism spectrum quotient, the Vineland Adaptive Behaviour Scale and the empathising and systemising quotient. Results established that the TR intervention increased empathising and reduced maladaptive behaviours. The findings also indicated that specific adaptive behaviours like socialization and communication were not affected by the intervention. Thus, a complex picture of the effects of this intervention emerges: while TR does not change all of the child’s behaviour, it can improve specific aspects of social functioning and also reduce maladaptive ASD traits

Compactifications of the moduli space of plane quartics and two lines

We study the moduli space of triples (C,L₁,L₂) consisting of quartic curves C and lines L₁ and L₂. Specifically, we construct and compactify the moduli space in two ways: via geometric invariant theory (GIT) and by using the period map of certain lattice polarized K3 surfaces. The GIT construction depends on two parameters t₁ and t₂ which correspond to the choice of a linearization. For t₁=t₂=1 we describe the GIT moduli explicitly and relate it to the construction via K3 surfaces