9,691 research outputs found

    The intrinsic electrical equivalent circuit of a laser diode

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    The basic electrical equivalent circuit of a laser diode is derived. The effects of spontaneous emission and self-pulsations are included. It is found that self-pulsations are represented by a negative resistance in the model. Application of this model suggests purely electronic methods of suppressing relaxation oscillations in laser diodes

    The oxygen-independent metabolism of cyclic monoterpenes in Castellaniella defragrans 65Phen

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    BACKGROUND: The facultatively anaerobic betaproteobacterium Castellaniella defragrans 65Phen utilizes acyclic, monocyclic and bicyclic monoterpenes as sole carbon source under oxic as well as anoxic conditions. A biotransformation pathway of the acyclic β-myrcene required linalool dehydratase-isomerase as initial enzyme acting on the hydrocarbon. An in-frame deletion mutant did not use myrcene, but was able to grow on monocyclic monoterpenes. The genome sequence and a comparative proteome analysis together with a random transposon mutagenesis were conducted to identify genes involved in the monocyclic monoterpene metabolism. Metabolites accumulating in cultures of transposon and in-frame deletion mutants disclosed the degradation pathway. RESULTS: Castellaniella defragrans 65Phen oxidizes the monocyclic monoterpene limonene at the primary methyl group forming perillyl alcohol. The genome of 3.95 Mb contained a 70 kb genome island coding for over 50 proteins involved in the monoterpene metabolism. This island showed higher homology to genes of another monoterpene-mineralizing betaproteobacterium, Thauera terpenica 58Eu(T), than to genomes of the family Alcaligenaceae, which harbors the genus Castellaniella. A collection of 72 transposon mutants unable to grow on limonene contained 17 inactivated genes, with 46 mutants located in the two genes ctmAB (cyclic terpene metabolism). CtmA and ctmB were annotated as FAD-dependent oxidoreductases and clustered together with ctmE, a 2Fe-2S ferredoxin gene, and ctmF, coding for a NADH:ferredoxin oxidoreductase. Transposon mutants of ctmA, B or E did not grow aerobically or anaerobically on limonene, but on perillyl alcohol. The next steps in the pathway are catalyzed by the geraniol dehydrogenase GeoA and the geranial dehydrogenase GeoB, yielding perillic acid. Two transposon mutants had inactivated genes of the monoterpene ring cleavage (mrc) pathway. 2-Methylcitrate synthase and 2-methylcitrate dehydratase were also essential for the monoterpene metabolism but not for growth on acetate. CONCLUSIONS: The genome of Castellaniella defragrans 65Phen is related to other genomes of Alcaligenaceae, but contains a genomic island with genes of the monoterpene metabolism. Castellaniella defragrans 65Phen degrades limonene via a limonene dehydrogenase and the oxidation of perillyl alcohol. The initial oxidation at the primary methyl group is independent of molecular oxygen

    On the line shape of the electrically detected ferromagnetic resonance

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    This work reviews and examines two particular issues related with the new technique of electrical detection of ferromagnetic resonance (FMR). This powerful technique has been broadly applied for studying magnetization and spin dynamics over the past few years. The first issue is the relation and distinction between different mechanisms that give rise to a photovoltage via FMR in composite magnetic structures, and the second is the proper analysis of the FMR line shape, which remains the "Achilles heel" in interpreting experimental results, especially for either studying the spin pumping effect or quantifying the spin Hall angles via the electrically detected FMR.Comment: 14 pages, 9 figure

    Measurement properties of the German version of the IKDC subjective knee form (IKDC-SKF).

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    PURPOSE: To examine the measurement properties of the German International Knee Documentation Committee Subjective Knee Form (IKDC-SKF) in knee disorder patients. METHODS: Three hundred twelve consecutive patients undergoing surgery for anterior cruciate ligament, meniscus and/or cartilage injuries completed the IKDC-SKF, Lysholm Score, Tegner Activity Scale, and Short Form-12 Health Survey before and 6 months post-surgery. IKDC-SKF measurement properties were calculated and patients were also asked to rate the relevance/comprehensibility of the questionnaire items. RESULTS: Reliability was good with high Cronbach's alpha and intraclass correlation coefficients, and standard error of measurement values of 4.4 to 6.0. The smallest detectable change (SDC) ranged from 12.3 to 16.7 points. Validity was good with 90% of all hypotheses confirmed. Confirmatory factor analysis did not show adequate fitting indices within the model. Over half of the items were rated as essential, and all were well comprehended. The majority of hypotheses for responsiveness were confirmed. No floor and ceiling effects were observed. The area under the curve ranged from 0.82 to 0.89 and the minimal important difference was smaller than the SDC. CONCLUSIONS: The German IKDC-SKF is a reliable outcome measure with good hypotheses testing and responsiveness, but its MIC and structural/content validity need further analysis

    Lifetime mental disorders and suicidal behaviour in South Africa

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    Background: There is relatively little data on the relationship between lifetime mental disorders and suicidal behaviour in low and middle income countries. This study examines the relationship between lifetime mental disorders, and subsequent suicide ideation, plans, and suicide attempts in South Africa. Method: A national survey of 4185 South African adults was conducted using the World Health Organization Composite International Diagnostic Interview (CIDI) to generate psychiatric diagnoses and suicidal behaviour. Bivariate, multivariate and discrete-time survival analyses were employed to investigate the associations between mental disorders and subsequent suicide ideation, plans, and attempts. Results: Sixty-one percent of people who seriously considered killing themselves at some point in their lifetime reported having a prior DSM-IV disorder. Mental disorders predict the onset of suicidal ideation, but have weaker effects in predicting suicide plans or attempts. After controlling for comorbid mental disorders, PTSD was the strongest predictor of suicidal ideation and attempts. There is a relationship between number of mental disorders and suicidal behaviour, with comorbidity having significantly sub-additive effects. Conclusion: Consistent with data from the developed world, mental disorders are strong predictors of suicidal behaviour, and these associations are more often explained by the prediction of ideation, rather than the prediction of attempts amongst ideators. This suggests some universality of the relevant mechanisms underlying the genesis of suicidal thoughts, and the progression to suicide attempts

    Three-dimensional imaging of vortex structure in a ferroelectric nanoparticle driven by an electric field

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    AbstractTopological defects of spontaneous polarization are extensively studied as templates for unique physical phenomena and in the design of reconfigurable electronic devices. Experimental investigations of the complex topologies of polarization have been limited to surface phenomena, which has restricted the probing of the dynamic volumetric domain morphology in operando. Here, we utilize Bragg coherent diffractive imaging of a single BaTiO3 nanoparticle in a composite polymer/ferroelectric capacitor to study the behavior of a three-dimensional vortex formed due to competing interactions involving ferroelectric domains. Our investigation of the structural phase transitions under the influence of an external electric field shows a mobile vortex core exhibiting a reversible hysteretic transformation path. We also study the toroidal moment of the vortex under the action of the field. Our results open avenues for the study of the structure and evolution of polar vortices and other topological structures in operando in functional materials under cross field configurations.</jats:p

    Stratifying quotient stacks and moduli stacks

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    Recent results in geometric invariant theory (GIT) for non-reductive linear algebraic group actions allow us to stratify quotient stacks of the form [X/H], where X is a projective scheme and H is a linear algebraic group with internally graded unipotent radical acting linearly on X, in such a way that each stratum [S/H] has a geometric quotient S/H. This leads to stratifications of moduli stacks (for example, sheaves over a projective scheme) such that each stratum has a coarse moduli space.Comment: 25 pages, submitted to the Proceedings of the Abel Symposium 201

    LOSS OF PHOSPHORUS BY RUNOFF FOR AGRICULTURAL WATERSHEDS

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    The loss of nutrients in runoff from agricultural land is a major cause of poor surface water quality in the United State. Scientists (NRCS) developed a technique to estimate the impact of agricultural watersheds on natural water resources. The objectives of this study were to apply this technique on the Wagon Train (WT),watershed to predict (1) loss of water by surface runoff, (2) loss of phosphorus (P) from soils by runoff and P loading for WT reservoir. The annual loss of water by runoff was estimated at 4.32 million m3 . The USGS data for a 50-year period (1951 to 2000) indicated that the average annual inflow for WT reservoir was 4.25 million m3 . The predicted annual P loss by runoff was 844 kg and could be considered as the annual loading for WT reservoir. The predicted P concentration in the runoff water at field sites was 196 μg/L. Phosphorus concentration observed in major streams at the beginning of spring (March) ranged from 99 μg/L to 240 μg/L with an average of 162 μg/L (S.D..= 40 μg/L), and the average P concentration in water samples taken from different locations in the reservoir was 140 μg/L. Phosphorus uptake by algae, weeds and aquatic plants, as well as high pH in the reservoir and streams might explain the slight drop of P concentration in waters. Further, the average P concentration observed in the main stream samples for the entire rainy season (March through October), ranged between 157 and 346 μg/L with an average of 267 μg/L (S.D. = 65 μg/L). Application of P fertilizers (April/May) for summer crops might explain the increase in P concentration. When factors affecting P concentration in streams are considered, the technique could provide a reasonable estimation of P concentration in stream water

    Arctic shipping emissions inventories and future scenarios

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    This paper presents 5 km×5 km Arctic emissions inventories of important greenhouse gases, black carbon and other pollutants under existing and future (2050) scenarios that account for growth of shipping in the region, potential diversion traffic through emerging routes, and possible emissions control measures. These high-resolution, geospatial emissions inventories for shipping can be used to evaluate Arctic climate sensitivity to black carbon (a short-lived climate forcing pollutant especially effective in accelerating the melting of ice and snow), aerosols, and gaseous emissions including carbon dioxide. We quantify ship emissions scenarios which are expected to increase as declining sea ice coverage due to climate change allows for increased shipping activity in the Arctic. A first-order calculation of global warming potential due to 2030 emissions in the high-growth scenario suggests that short-lived forcing of ~4.5 gigagrams of black carbon from Arctic shipping may increase global warming potential due to Arctic ships' CO&lt;sub&gt;2&lt;/sub&gt; emissions (~42 000 gigagrams) by some 17% to 78%. The paper also presents maximum feasible reduction scenarios for black carbon in particular. These emissions reduction scenarios will enable scientists and policymakers to evaluate the efficacy and benefits of technological controls for black carbon, and other pollutants from ships
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