Electron and ion kinetic effects in the saturation of a driven ion acoustic wave

The role of ion and electron kinetic effects is investigated in the context of the nonlinear saturation of a driven ion acoustic wave(IAW) and its parametric decay into subharmonics. The simulations are carried out with a full–particle-in-cell (PIC) code, in which both ions and electrons are treated kinetically. The full-PIC results are compared with those obtained from a hybrid-PIC code (kinetic ions and Boltzmann electrons). It is found that the largest differences between the two kinds of simulations take place when the IAW is driven above the ion wave-breaking limit. In such a case of a strong drive, the hybrid-PIC simulations lead to a Berstein-Greene-Kruskal-like nonlinear IAW of a large amplitude, while in the full-PIC the IAW amplitude decays to a small level after a transient stage. The electron velocity distribution function is significantly flattened in the domain of small electron velocities. As a result the nonlinear frequency shift due to the electron kinetic effects compensates partly the nonlinear frequency shift due to the ion kinetic effects, allowing then for the parametric decay of the driven IAW into subharmonics. These observations lead to the conclusion that electron kinetic effects become important whenever the nonlinear effects come into play

Detailed characterization of laser-produced astrophysically-relevant jets formed via a poloidal magnetic nozzle

International audienc

Plasma Dynamics

Contains table of contents for Section 2 and reports on two research projects.Princeton University/National Spherical Torus Experiment Grant S04020G PPPLU.S. Department of Energy Grant DE-FGO2-91-ER-54109National Science Foundation Grant ECS 94-24282Los Alamos National Laboratory Grant No. E29060017

Plasma Dynamics

Contains table of contents for Section 2 and reports on three research projects.U.S. Navy - Office of Naval Research Grant N00014-90-J-4130National Science Foundation Contract ATM 94-24282U.S. Department of Energy Contract DE-FG02-91-ER-54109U.S. Department of Energy Tokamak Fusion Test Reactor Contract DE-AC02-78-ET-5101

Plasma Dynamics

Contains table of contents for Section 2 and reports on four research projects.National Science Foundation Grant ECS-89-02990U.S. Air Force - Office of Scientific Research Grant AFOSR 89-0082-CU.S. Army - Harry Diamond Laboratories Contract DAAL02-89-K-0084U.S. Army - Harry Diamond Laboratories Contract DAAL02-92-K-0037U.S. Department of Energy Contract DE-AC02-90ER-40591U.S. Navy - Office of Naval Research Grant N00014-90-J-4130Lawrence Livermore National Laboratories Subcontract B-160456National Aeronautics and Space Administration Grant NAGW-2048National Science Foundation Grant ECS-88-22475U.S. Department of Energy Grant DE-FG02-91-ER-5410

Plasma Dynamics

Contains table of contents for Section 2 and reports on three research projects.U.S. Navy - Office of Naval Research Grant N00014-90-J-4130Princeton University/Tokamak Physics Experiment Grant S-03688-GU.S. Department of Energy Grant DE-FG02-91-ER-54109National Science Foundation Grant ATM 94-2428

Plasma Dynamics

Contains table of contents for Section 2 and reports on three research projects.National Science Foundation Grant ECS 89-02990U.S. Air Force - Office of Scientific Research Grant F49620-93-1-0108U.S. Army - Harry Diamond Laboratories Contract DAAL02-92-K-0037U.S. Department of Energy Grant DE-FG02-91-ER-40648U.S. Navy - Office of Naval Research Grant N00014-90-J-4130National Aeronautics and Space Administration Grant NAGW-2048National Science Foundation Grant ECS 88-22475U.S. Department of Energy Grant DE-FG02-91-ER-54109Magnetic Fusion Science Fellowship Progra

Patient and Clinician Perceptions of Precision Cardiology Care: Findings From the HeartCare Study

BACKGROUND: Routine genome-wide screening for cardiovascular disease risk may inform clinical decision-making. However, little is known about whether clinicians and patients would find such testing useful or acceptable within the context of a genomics-enabled learning health system. METHODS: We conducted surveys with patients and their clinicians who were participating in the HeartCare Study, a precision cardiology care project that returned results from a next-generation sequencing panel of 158 genes associated with cardiovascular disease risk. Six weeks after return of results, we assessed patients\u27 and clinicians\u27 perceived utility and disutility of HeartCare, the effect of the test on clinical recommendations, and patients\u27 attitudes toward integration of research and clinical care. RESULTS: Among 666 HeartCare patients with a result returned during the survey study period, 42.0% completed a full or partial survey. Patient-participants who completed a full survey (n=224) generally had positive perceptions of HeartCare independent of whether they received a positive or negative result. Most patient-participants considered genetic testing for cardiovascular disease risk to have more benefit than risk (88.3%) and agreed that it provided information that they wanted to know (81.2%), while most disagreed that the test caused them to feel confused (77.7%) or overwhelmed (78.0%). For 122 of their patients with positive results, clinicians (n=13) reported making changes in clinical care for 66.4% of patients, recommending changes in health behaviors for 36.9% of patients, and recommending to 33.6% of patients that their family members have clinical testing. CONCLUSIONS: Both patients and clinicians thought the HeartCare panel screen for cardiovascular disease risk provided information that was useful in terms of personal or health benefits to the patient and that informed clinical care without causing patients to be confused or overwhelmed. Further research is needed to assess perceptions of genome-wide screening among the US cardiology clinic population