11,506 research outputs found

    Necessarily Hypocritical: The Legal Viability of EPA\u27s Regulation of Stationary Source Greenhouse Gas Emissions Under the Clean Air Act

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    The Supreme Court’s ruling in Massachusetts v. EPA made clear that greenhouse gases fall within the realm of air pollutants the Clean Air Act was designed to regulate. The Court’s decision sparked a chain reaction forcing the EPA to regulate greenhouse gases under different provisions of the Act. The EPA’s decision to regulate drew fierce criticism, especially from industries that would be forced to reduce emissions. Opponents argue that greenhouse gases are not traditional pollutants and therefore the drafters of the Clean Air Act did not intend them to be regulated. Furthermore, they argue that the EPA over-stepped its authority in “tailoring” a new rule to incorporate greenhouse gases more appropriately into the Act’s framework. This Note defends the EPA’s decision to regulate greenhouse gases, as well as its Tailoring Rule. In light of the Clean Air Act’s explicit language and legislative intent, the EPA was not only legally justified in implements its decision, but it had no other choice

    Advanced expander test bed program

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    The Advanced Expander Test Bed (AETB) is a key element in NASA's Space Chemical Engine Technology Program for development and demonstration of expander cycle oxygen/hydrogen engine and advanced component technologies applicable to space engines as well as launch vehicle upper stage engines. The AETB will be used to validate the high-pressure expander cycle concept, investigate system interactions, and conduct investigations of advanced mission focused components and new health monitoring techniques in an engine system environment. The split expander cycle AETB will operate at combustion chamber pressures up to 1200 psia with propellant flow rates equivalent to 20,000 lbf vacuum thrust. Contract work began 27 Apr. 1990. During 1992, a major milestone was achieved with the review of the final design of the oxidizer turbopump in Sep. 1992

    Wilson Loops and Area-Preserving Diffeomorphisms in Twisted Noncommutative Gauge Theory

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    We use twist deformation techniques to analyse the behaviour under area-preserving diffeomorphisms of quantum averages of Wilson loops in Yang-Mills theory on the noncommutative plane. We find that while the classical gauge theory is manifestly twist covariant, the holonomy operators break the quantum implementation of the twisted symmetry in the usual formal definition of the twisted quantum field theory. These results are deduced by analysing general criteria which guarantee twist invariance of noncommutative quantum field theories. From this a number of general results are also obtained, such as the twisted symplectic invariance of noncommutative scalar quantum field theories with polynomial interactions and the existence of a large class of holonomy operators with both twisted gauge covariance and twisted symplectic invariance.Comment: 23 page

    Insights into the G-rich VEGF-binding aptamer V7t1: when two G-quadruplexes are better than one!

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    The G-quadruplex-forming VEGF-binding aptamer V7t1 was previously found to be highly polymorphic in a K+-containing solution and, to restrict its conformational preferences to a unique, well-defined form, modified nucleotides (LNA and/or UNA) were inserted in its sequence. We here report an in-depth biophysical characterization of V7t1 in a Na+-rich medium, mimicking the extracellular environment in which VEGF targeting should occur, carried out combining several techniques to analyse the conformational behaviour of the aptamer and its binding to the protein. Our results demonstrate that, in the presence of high Na+ concentrations, V7t1 behaves in a very different way if subjected or not to annealing procedures, as evidenced by native gel electrophoresis, size exclusion chromatography and dynamic light scattering analysis. Indeed, not-annealed V7t1 forms both monomeric and dimeric G-quadruplexes, while the annealed oligonucleotide is a monomeric species. Remarkably, only the dimeric aptamer efficiently binds VEGF, showing higher affinity for the protein compared to the monomeric species. These findings provide new precious information for the development of improved V7t1 analogues, allowing more efficient binding to the cancer-related protein and the design of effective biosensors or theranostic devices based on VEGF targeting

    Statistical analysis of correlations and intermittency of a turbulent rotating column in a magnetoplasma device

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    12th International Congress on Plasma Physics, 25-29 October 2004, Nice (France)A detailed statistical analysis of density fluctuations in the cylindrical non-fusion device "Mistral" is performed. The experimental set-up is implemented in order to reach turbulent behavior in the rotating plasma column. Two different turbulent regimes are obtained corresponding to two selected sets of values for the anode potential and the biasing of the collecting plate. The first regime displays a slowly-rotating column characterized by the presence of a shear layer separating the plasma bulk from the scrape-off layer (SOL), the latter showing a strong intermittent behavior. The second regime corresponds to a weakly-rotating column in which coherence is lost in the plasma bulk and a standard diffusive process takes place in the SOL. These findings are supported by the calculation of the Hurst exponent of the turbulent signals using Wavelet-analysis techniques

    The absolute age of the globular cluster M15 using near-infrared adaptive optics images from PISCES/LBT

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    We present deep near-infrared (NIR) J, Ks photometry of the old, metal-poor Galactic globular cluster M\,15 obtained with images collected with the LUCI1 and PISCES cameras available at the Large Binocular Telescope (LBT). We show how the use of First Light Adaptive Optics system coupled with the (FLAO) PISCES camera allows us to improve the limiting magnitude by ~2 mag in Ks. By analyzing archival HST data, we demonstrate that the quality of the LBT/PISCES color magnitude diagram is fully comparable with analogous space-based data. The smaller field of view is balanced by the shorter exposure time required to reach a similar photometric limit. We investigated the absolute age of M\,15 by means of two methods: i) by determining the age from the position of the main sequence turn-off; and ii) by the magnitude difference between the MSTO and the well-defined knee detected along the faint portion of the MS. We derive consistent values of the absolute age of M15, that is 12.9+-2.6 Gyr and 13.3+-1.1 Gyr, respectively.Comment: 13 pages, 8 figures, ApJ accepte

    Fluctuations of company yearly profits versus scaled revenue: Fat tail distribution of Levy type

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    We analyze annual revenues and earnings data for the 500 largest-revenue U.S. companies during the period 1954-2007. We find that mean year profits are proportional to mean year revenues, exception made for few anomalous years, from which we postulate a linear relation between company expected mean profit and revenue. Mean annual revenues are used to scale both company profits and revenues. Annual profit fluctuations are obtained as difference between actual annual profit and its expected mean value, scaled by a power of the revenue to get a stationary behavior as a function of revenue. We find that profit fluctuations are broadly distributed having approximate power-law tails with a Levy-type exponent α1.7\alpha \simeq 1.7, from which we derive the associated break-even probability distribution. The predictions are compared with empirical data.Comment: 6 pages, 6 figure

    Etiological diagnosis, prognostic significance and role of electrophysiological study in patients with Brugada ECG and syncope.

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    BACKGROUND: Syncope is considered a risk factor for life-threatening arrhythmias in Brugada patients. Distinguishing a benign syncope from one due to ventricular arrhythmias is often difficult, unless an ECG is recorded during the episode. Aim of the study was to analyze the characteristics of syncopal episodes in a large population of Brugada patients and evaluate the role of electrophysiological study (EPS) and the prognosis in the different subgroups. METHODS AND RESULTS: One hundred ninety-five Brugada patients with history of syncope were considered. Syncope were classified as neurally mediated (group 1, 61%) or unexplained (group 2, 39%) on the basis of personal and family history, clinical features, triggers, situations, associated signs, concomitant therapy. Most patients underwent EPS; they received ICD or implantable loop-recorder on the basis of the result of investigations and physician's judgment. At 62±45months of mean follow-up, group 1 showed a significantly lower incidence of arrhythmic events (2%) as compared to group 2 (9%, p<0.001). Group 2 patients with positive EPS showed the highest risk of arrhythmic events (27%). No ventricular events occurred in subjects with negative EPS. CONCLUSION: Etiological definition of syncope in Brugada patients is important, as it allows identifying two groups with different outcome. Patients with unexplained syncope and ventricular fibrillation induced at EPS have the highest risk of arrhythmic events. Patients presenting with neurally mediated syncope showed a prognosis similar to that of the asymptomatic and the role of EPS in this group is unproven
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