437 research outputs found
Analysis of the mechanical behaviour of a 11.5 T Nb3Sn LHC dipole magnet according to the ring collar concept
According to the CERN-LHC (Large Hadron Collider) reference design, 10-tesla twin-aperture NbTi dipoles will be built with split collars that enclose both apertures. As part of the development program towards an experimental 11.5-tesla Nb3Sn LHC dipole magnet, the mechanical implications of an alternative collar concept have been studied with a finite element analysis. In this concept ring shaped collars are shrunk on each finished single aperture coil, thus providing the necessary room-temperature prestress. This system results in a major improvement of the stress distribution in the collars. It is noted that introduction of friction at the sliding planes can cause reopening of the gap between the yoke halves during excitation. This depends strongly on the value of the friction coefficient
Limits and possibilities of surgical treatment of locally advanced prostatic carcinoma
Prostatic carcinoma is the second most diagnosed malignant tumor in the Netherlands, only
carcinoma of the lung is more frequent. In 1991 4343 men were diagnosed with prostate
cancer, making up 14.1% of all diagnosed malignant tumors. In the age-group 60-74 years the
incidence was second after pulmonary carcinoma, and in the age-group >75 years it is the most
frequently diagnosed malignancy. In 1991 2108 patients died because of prostate cancer. The
mortality/incidence ratio is 0,49; which means that about 50% of the patients will die because
of their prostatic malignancy. The incidence of prostatic cancer in developed countries is
rising. Lu-Yao reported an increase in the incidence-rates of prostatic cancer in the United
States of America of6.4% per year between 1983 and 1989'. This increase appeared to be
due to the detection of early-stage disease, but there was no increase in the incidence-rate of
metastatic cancer. There was no increase in mortality rates during this study-period. In the
Netherlands 3% of all mortality among men was due to prostate cancer (1989) 3. In 1994 van
der Gulden reported on the trends in mortality-rates for patients with prostate cancer in the
Netherlands'. The age-adjusted mortality-rates rose between 1950 and 1989 with an average
increase of 1 % per year. A continuous increase of mortality from prostate cancer was found in
consecutive birth-cohorts (defined by combining age and calender-time periods on the basis of
their central year of birth). There was a steep rise in the mortality from prostate cancer with
age; for the age-category 55-59 years the prostate cancer mortality-rate was 11.2 per 100.000
man-years, but for the category >85 years this was 921.8. This rise in the incidence and mortality
of prostate cancer points out that this disease will become more and more important in the
years to come. Since more cancers tend to be localized, the role of radical prostatectomy in the
treatment of prostatic carcinoma will become even more important than it is today
Development of an experimental 10 T Nb3Sn dipole magnet for the CERN LHC
An experimental 1-m long twill aperture dipole magnet developed using a high-current Nb3Sn conductor in order to attain a magnetic field well beyond 10 T at 4.2 K is described. The emphasis in this Nb3Sn project is on the highest possible field within the known Large Hadron Collider (LHC) twin-aperture configuration. A design target of 11.5 T was chosen
A Dual Role for Prediction Error in Associative Learning
Confronted with a rich sensory environment, the brain must learn statistical regularities across sensory domains to construct causal models of the world. Here, we used functional magnetic resonance imaging and dynamic causal modeling (DCM) to furnish neurophysiological evidence that statistical associations are learnt, even when task-irrelevant. Subjects performed an audio-visual target-detection task while being exposed to distractor stimuli. Unknown to them, auditory distractors predicted the presence or absence of subsequent visual distractors. We modeled incidental learning of these associations using a Rescorla-Wagner (RW) model. Activity in primary visual cortex and putamen reflected learning-dependent surprise: these areas responded progressively more to unpredicted, and progressively less to predicted visual stimuli. Critically, this prediction-error response was observed even when the absence of a visual stimulus was surprising. We investigated the underlying mechanism by embedding the RW model into a DCM to show that auditory to visual connectivity changed significantly over time as a function of prediction error. Thus, consistent with predictive coding models of perception, associative learning is mediated by prediction-error dependent changes in connectivity. These results posit a dual role for prediction-error in encoding surprise and driving associative plasticit
Critical current degradation in HTS wires due to cyclic mechanical strain
HTS wires, which may be used in many devices such as magnets and rotating machines, may be subjected to mechanical strains from electromagnetic, thermal and centripetal forces. In some applications these strains will be repeated several thousand times during the lifetime of the device. We have measured critical current degradation due to repeated strain cycles for both compressive and tensile strains. Results for BSCCO-2223 HTS conductor samples are presented for strain values up to 0.5% and cycle numbers up to and beyond 10/sup 4/
NbSn conductor development and characterization for NED
The main purpose of Next European Dipole (NED) project is to design and to build an NbSn ~ 15 T dipole magnet. Due to budget constraints, NED is mainly focused on superconducting cable development and production. In this work, an update is given on the NED conductor development by Alstom-MSA and SMI, which uses, respectively, Internal-Tin-Diffusion and Powder-In-Tube methods, with the aim of reaching a non-copper critical current density of ~ 3000 A/mm2 at 12 T and 4.2 K. Characterization results, including critical current and magnetization data, are presented and discussed, as well, for conductors already developed by both companies for this project. SMI succeeded to produce a strand with 50 Ôm diameter filaments and with a critical current of ~ 1400 A at 4.2 K and 12àT, corresponding to a non-copper critical current density of ~ 2500 A/mm2. Cabling trials with this strand were successfully carried out at LBNL
Sex-specific effects of wind on the flight decisions of a sexually-dimorphic soaring bird
1. In a highly dynamic airspace, flying animals are predicted to adjust foraging behaviour to variable wind conditions to minimize movement costs.
2. Sexual size dimorphism is widespread in wild animal populations, and for large soaring birds which rely on favourable winds for energyâefficient flight, differences in morphology, wing loading and associated flight capabilities may lead males and females to respond differently to wind. However, the interaction between wind and sex has not been comprehensively tested.
3. We investigated, in a large sexually dimorphic seabird which predominantly uses dynamic soaring flight, whether flight decisions are modulated to variation in winds over extended foraging trips, and whether males and females differ.
4. Using GPS loggers we tracked 385 incubation foraging trips of wandering albatrosses Diomedea exulans , for which males are c . 20% larger than females, from two major populations (Crozet and South Georgia). Hidden Markov models were used to characterize behavioural statesâdirected flight, areaârestricted search (ARS) and restingâand model the probability of transitioning between states in response to wind speed and relative direction, and sex.
5. Wind speed and relative direction were important predictors of state transitioning. Birds were much more likely to take off (i.e. switch from rest to flight) in stronger headwinds, and as wind speeds increased, to be in directed flight rather than ARS. Males from Crozet but not South Georgia experienced stronger winds than females, and males from both populations were more likely to takeâoff in windier conditions.
6. Albatrosses appear to deploy an energyâsaving strategy by modulating takingâoff, their most energetically expensive behaviour, to favourable wind conditions. The behaviour of males, which have higher wing loading requiring faster speeds for gliding flight, was influenced to a greater degree by wind than females. As such, our results indicate that variation in flight performance drives sex differences in timeâactivity budgets and may lead the sexes to exploit regions with different wind regimes
The CARE accelerator R&D programme in Europe
Published online on JACoWCARE, an ambitious and coordinated programme of accelerator research and developments oriented towards high energy physics projects, has been launched in January 2004 by the main European laboratories and the European Commission. This project aims at improving existing infrastructures dedicated to future projects such as linear colliders, upgrades of hadron colliders and high intensity proton drivers. We describe the CARE R&D plans, mostly devoted to advancing the performance of the superconducting technology, both in the fields of RF cavities for electron or proton acceleration and of high field magnets, as well as to developing high intensity electron and proton injectors. We highlight some results and progress obtained so far
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