404 research outputs found
Notable College Experiences Through Original Still Photography
https://lib.dr.iastate.edu/carver_narratives/1000/thumbnail.jp
Results and prospects on registration of reflected Cherenkov light of EAS from cosmic particles above 10^{15} eV
We give an overview of the SPHERE experiment based on detection of reflected
Vavilov-Cherenkov radiation (Cherenkov light) from extensive air showers in the
energy region E>10^{15} eV. A brief history of the reflected Cherenkov light
technique is given; the observations carried out with the SPHERE-2 detector are
summarized; the methods of the experimental datasample analysis are described.
The first results on the primary cosmic ray all-nuclei energy spectrum and mass
composition are presented. Finally, the prospects of the SPHERE experiment and
the reflected Cherenkov light technique are given.Comment: 4 pages, 3 figures, Proc. PANIC-201
Sharing the proceeds from a hierarchical venture
We consider the problem of distributing the proceeds generated from a joint venture in which the participating agents are hierarchically organized. We introduce and characterize a family of allocation rules where revenue ‘bubbles up’ in the hierarchy. The family is flexible enough to accommodate the no-transfer rule where no revenue bubbles up) and the full-transfer rule (where all the revenues bubble up to the top of the hierarchy). Intermediate rules within the family are reminiscent of popular incentive mechanisms for social mobilization or multi-level marketing
Analysis of Pumping Rings
A slightly tapered ring riding on a reciprocating shaft can be used as a pump, pumping capacity of these rings is analyzed. Th
Mapping the Naked Neck (NA) and Polydactyly (PO) mutants of the chicken with microsatellite molecular markers
Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.
Gas1 and Boc/Cdon act as co-receptors in the vertebrate Hedgehog signalling pathway, but the nature of their interaction with the primary Ptch1/2 receptors remains unclear. Here we demonstrate, using primordial germ cell migration in mouse as a developmental model, that specific hetero-complexes of Ptch2/Gas1 and Ptch1/Boc mediate the process of Smo de-repression with different kinetics, through distinct modes of Hedgehog ligand reception. Moreover, Ptch2-mediated Hedgehog signalling induces the phosphorylation of Creb and Src proteins in parallel to Gli induction, identifying a previously unknown Ptch2-specific signal pathway. We propose that although Ptch1 and Ptch2 functionally overlap in the sequestration of Smo, the spatiotemporal expression of Boc and Gas1 may determine the outcome of Hedgehog signalling through compartmentalisation and modulation of Smo-downstream signalling. Our study identifies the existence of a divergent Hedgehog signal pathway mediated by Ptch2 and provides a mechanism for differential interpretation of Hedgehog signalling in the germ cell niche
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