SOIL EROSION EVALUATION IN THE RASTOCKI POTOK WATERSHED OF MONTENEGRO USING THE EROSION POTENTIAL METHOD

Soil erosion is the most important factor of land degradation worldwide, causing significant environmental problems in the region of South East Europe also. We studied soil erosion processes in the RastockiPotok Watershed of Montenegro using the Erosion Potential Method (EPM) of Gavrilovic, which is created in Yugoslavia and is the most suitable on catchment level for the watershed management needs in this Region. The peak discharge (Qmax) is calculated on 150 m3s-1 and there is a possibility for large flood waves to appear in the studied basin. According to our analysis, the coefficient fs, (portion under forest) is 0.45; ft (grass) is 0.41 and fg (bare land) is 0.14 and the coefficient of the river basin planning, Xa, is 0.52. Real soil losses, Gyr, were calculated on 1472m3yr-1, specific 250m3km-2yr-1. The value of the Z coefficient of 0.488 indicates that the studied watershed belongs in the Destruction Category III: the erosion process is medium. This study confirmed the findings of the other Balkan researchers that the EPM method of Professor Gavrilovic is a useful tool for calculating sediment yield in the South East Europe

Interleukin-18 Is a Potential Biomarker Linking Dietary Fatty Acid Quality and Insulin Resistance: Results from a Cross-Sectional Study in Northern Italy

Dietary lipids are pivotal in modulating metabolic inflammation. Among the inflammatory mediators characterizing metabolic inflammation, interleukin 18 (IL-18) has been consistently associated with obesity and insulin resistance. This study aims to evaluate whether the quality of lipid intake impacts upon IL-18 plasma levels and the implications on insulin resistance computed by the homeostatic model assessment for insulin resistance (HOMA-IR). Using a cross-sectional design, this study confirmed that IL-18 correlated positively with insulin resistance and individuals with a HOMA-IR ≥ 2.5 displayed higher circulating IL-18 levels compared with their insulin-sensitive counterparts. In terms of the effect of the quality of dietary lipids on IL-18 circulating levels, the ratio between monounsaturated, omega-3, polyunsaturated and saturated fatty acids as well as the intake of eicosapentaenoic and docosahexaenoic acids correlated negatively with IL-18. Despite this, IL-18 circulating levels, but not dietary fatty acid quality, predicted insulin resistance. Nevertheless, the ratio between omega 3 and saturated fatty acids was a predictor of IL-18 plasma levels. Thus, the downregulation of IL-18 may underpin, at least partially, the beneficial metabolic effects of substituting omega 3 for saturated fatty acids with this cytokine potentially representing a biomarker linking dietary lipids and metabolic outcomes

Irisin Attenuates Muscle Impairment during Bed Rest through Muscle-Adipose Tissue Crosstalk

The detrimental effect of physical inactivity on muscle characteristics are well known. Irisin, an exercise-induced myokine cleaved from membrane protein fibronectin type III domain-containing protein-5 (FNDC5), mediates at least partially the metabolic benefits of exercise. This study aimed to assess the interplay between prolonged inactivity, circulating irisin, muscle performance, muscle fibers characteristics, as well as the FNDC5 gene expression (FNDC5ge) in muscle and adipose tissue among healthy subjects. Twenty-three healthy volunteers were tested before and after 14 days of Bed Rest, (BR). Post-BR circulating levels of irisin significantly increased, whereas body composition, muscle performance, and muscle fiber characteristics deteriorated. Among the subjects achieving the highest post-BR increase of irisin, the lowest reduction in maximal voluntary contraction and specific force of Fiber Slow/1, the highest increase of FNDC5ge in adipose tissue, and no variation of FNDC5ge in skeletal muscle were recorded. Subjects who had the highest FNDC5ge in adipose tissue but not in muscle tissue showed the highest circulating irisin levels and could better withstand the harmful effect of BR

Impact of Excess Auditor Remuneration on the Cost of Equity Capital around the World

This study examines the relation between excess auditor remuneration and the implied required rate of return (IRR hereafter) on equity capital in global markets. We conjecture that when auditor remuneration is excessively large, investors may perceive the auditor to be economically bonded to the client, leading to a lack of independence. This perceived lack of independence increases the information risk associated with the credibility of financial statements, thereby increasing IRR. Consistent with this notion, we find that IRR is increasing in excess auditor remuneration, but only in countries with stronger investor protection. Finding evidence of a relation only in stronger investor protection countries is consistent with the more prominent role of audited financial statements for investors' decisions in these countries. In settings in which investors are less likely to rely on audited financial statements and instead rely on alternative sources of information (i.e., in countries with weaker investor protection), the impact of client-auditor bonding should have less of an effect on investors' decisions.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline

Greater maintenance of bone mineral content in male than female athletes, and in sprinting and jumping than endurance athletes: a longitudinal study of bone strength in elite masters athletes

Summary: We investigated longitudinal changes in tibia bone strength in master power (jumping and sprinting) and endurance (distance) athletes of both sexes. Bone mass but not cross‐sectional moment of inertia was better maintained in power than endurance athletes over time, particularly in men and independent of changes in performance. Objective: Assessment of effects of sex and athletic discipline (lower limb power events e.g. sprint running and jumping versus endurance running events) on longitudinal changes in bone strength in masters athletes. Methods: We examined tibia and fibula bone properties at distal (4% distal‐proximal tibia length) and proximal (66% length) sites using peripheral quantitative computed tomography (pQCT) in seventy‐one track and field masters athletes (30 male, 41 female, age at baseline 57.0±12.2y) in a longitudinal cohort study that included at least two testing sessions over a mean period of 4.2±3.1y. Effects of time, as well as time*sex and time*discipline interactions on bone parameters and calf muscle cross‐sectional area (CSA) were examined. Results: Effects of time were sex and discipline‐dependent, even following adjustment for enrolment age, sex, and changes in muscle CSA and athletic performance. Male sex and participation in power events was associated with better maintenance of tibia bone mineral content (BMC, an indicator of bone compressive strength) at 4% and 66% sites. In contrast, there was no strong evidence of sex or discipline effects on cross‐sectional moment of inertia (CSMI, an indicator of bone bending and torsional strength – P > 0.3 for interactions). Similar sex and discipline‐specific changes were also observed in the fibula. Conclusions: Results suggest that male athletes and those participating in lower limb power‐based rather than endurance‐based disciplines have better maintenance of bone compressive but not bending and torsional strength

Amelioration of sexual adverse effects in the early breast cancer patient

As the number of breast cancer survivors increases, the long term consequences of breast cancer treatment are gaining attention. Sexual dysfunction is a common complaint amongst breast cancer survivors, and there are few evidence based recommendations and even fewer well designed clinical trials to establish what treatments are safe or effective in this patient population. We conducted a PubMed search for articles published between 1995–2009 containing the terms breast cancer, sexual dysfunction, libido, vaginal dryness, testosterone, and vaginal estrogen. We initially reviewed articles focusing exclusively on sexual issues in breast cancer patients. Given the paucity of clinical trials addressing sexual issues in breast cancer patients, we also included studies evaluating both hormone and non-hormone based interventions for sexual dysfunction in post-menopausal women in general. Among breast cancer survivors, vaginal dryness and loss of libido represent some of the most challenging long term side effects of breast cancer treatment. In the general post-menopausal population, topical preparations of estrogens and testosterone both appear to improve sexual function; however there are conflicting reports about the efficacy and safety of these interventions in women with a history of breast cancer, and further research is warranted