Kinematic, kinetic and electromyographic response to customized foot orthoses in patients with tibialis posterior tenosynovitis, pes plano valgus and rheumatoid arthritis

Objective. To describe the effect of customized foot orthoses (FOs) on the kinematic, kinetic and EMG features in patients with RA, tibialis posterior (TP) tenosynovitis and associated pes plano valgus.<p></p> Methods. Patients with RA and US-confirmed tenosynovitis of TP underwent gait analysis, including three-dimensional (3D) kinematics, kinetics, intramuscular EMG of TP and surface EMG of tibialis anterior, peroneus longus, soleus and medial gastrocnemius. Findings were compared between barefoot and shod with customized FO conditions.<p></p> Results. Ten patients with RA with a median (range) disease duration of 3 (1–18) years were recruited. Moderate levels of foot pain and foot-related impairment and disability were present with moderately active disease states. Altered timing of the soleus (P = 0.05) and medial gastrocnemius (P = 0.02) and increased magnitude of tibialis anterior (P = 0.03) were noted when barefoot was compared with shod with FO. Trends were noted for reduced TP activity in the contact period (P = 0.09), but this did not achieve statistical significance. Differences in foot motion characteristics were recorded for peak rearfoot eversion (P = 0.01), peak rearfoot plantarflexion (P < 0.001) and peak forefoot abduction (P = 0.02) in the shod with FOs compared with barefoot conditions. No differences in kinetic variables were recorded.<p></p> Conclusion. This study has demonstrated, for the first time, alterations in muscle activation profiles and foot motion characteristics in patients with RA, pes plano valgus and US-confirmed TP tenosynovitis in response to customized FOs. Complex adaptations were evident in this cohort and further work is required to determine whether these functional alterations lead to improvements in patient symptoms.<p></p&gt

Penicillin Allergy Assessment and Skin Testing in the Outpatient Setting

Penicillin allergies are among of the most commonly reported allergies, yet only 10% of these patients are truly allergic. This leads to potential inadvertent negative consequences for patients and makes treatment decisions challenging for clinicians. Thus, allergy assessment and penicillin skin testing (PST) are important management strategies to reconcile and clarify labeled penicillin allergies. While PST is more common in the inpatient setting where the results will immediately impact antibiotic management, this process is becoming of increasing importance in the outpatient setting. PST in the outpatient setting allows clinicians to proactively de-label and educate patients accordingly so beta-lactam antibiotics may be appropriately prescribed when necessary for future infections. While allergists have primarily been responsible for PST in the outpatient setting, there is an increasing role for pharmacist involvement in the process. This review highlights the importance of penicillin allergy assessments, considerations for PST in the outpatient setting, education and advocacy for patients and clinicians, and the pharmacist’s role in outpatient PST

Attributes Preferred and Premiums Offered for Naturally Produced Beef Cattle

A growing number of beef cattle producers in the US are using limited information to determine whether or not it would be economical for them to grow naturally produced cattle. The objective was to discover the attributes that marketing companies prefer for the naturally produced cattle they purchase, and to elicit the price premiums being offered for cattle that possess these attributes. Results of a phone survey of companies that purchase natural cattle show that 27 out of 32 companies report their willingness to pay a premium of $5.95/cwt for cattle that have never received antibiotics, ionophores, hormones or animal by-products.Key words: attributes, beef, cattle, naturally produced, premiums, Agribusiness, Food Consumption/Nutrition/Food Safety, Livestock Production/Industries, Marketing,

Osmium Isotope Systematics of Ureilites

The Os-187/Os-188 for twenty-two ureilite whole rock samples, including monomict, augite-bearing, and polymict lithologies, were examined in order to constrain the provenance and subsequent magmatic processing of the ureilite parent body (or bodies). The Re/Os ratios of most ureilites show evidence for a recent disturbance, probably related to Re mobility during weathering, and no meaningful chronological information can be extracted from the present data set. The ureilite Os-187/Os-188 ratios span a range from 0.11739 to 0.13018, with an average of 0.1258+/-0.0023 (1(sigma)), similar to typical carbonaceous chondrites, and distinct from ordinary or enstatite chondrites. The similar mean of Os-187/Os-188 measured for the ureilites and carbonaceous chondrites suggests that the ureilite parent body probably formed within the same region of the solar nebula as carbonaceous chondrites. From the narrow range of the 187Os/188Os distribution in ureilite meteorites it is further concluded that Re was not significantly fractionated from Os during planetary differentiation and was not lost along with the missing ureilitic melt component. The lack of large Re/Os fractionations requires that Re/Os partitioning was controlled by a metal phase, and thus metal had to be stable throughout the interval of magmatic processing on the ureilite parent body

Morphological Classification of Galaxies by Shapelet Decomposition in the Sloan Digital Sky Survey II: Multiwavelength Classification

We describe the application of the `shapelet' linear decomposition of galaxy images to multi-wavelength morphological classification using the $u,g,r,i,$ and $z$-band images of 1519 galaxies from the Sloan Digital Sky Survey. We utilize elliptical shapelets to remove to first-order the effect of inclination on morphology. After decomposing the galaxies we perform a principal component analysis on the shapelet coefficients to reduce the dimensionality of the spectral morphological parameter space. We give a description of each of the first ten principal component's contribution to a galaxy's spectral morphology. We find that galaxies of different broad Hubble type separate cleanly in the principal component space. We apply a mixture of Gaussians model to the 2-dimensional space spanned by the first two principal components and use the results as a basis for classification. Using the mixture model, we separate galaxies into three classes and give a description of each class's physical and morphological properties. We find that the two dominant mixture model classes correspond to early and late type galaxies, respectively. The third class has, on average, a blue, extended core surrounded by a faint red halo, and typically exhibits some asymmetry. We compare our method to a simple cut on $u-r$ color and find the shapelet method to be superior in separating galaxies. Furthermore, we find evidence that the $u-r=2.22$ decision boundary may not be optimal for separation between early and late type galaxies, and suggest that the optimal cut may be $u-r \sim 2.4$.Comment: 42 pages, 18 figs, revised version in press at AJ. Some modification to the technique, more discussion, addition/deletion/modification of several figures, color figures have been added. A high resolution version may be obtained at http://bllac.as.arizona.edu/~bkelly/shapelets/shapelets_ugriz.ps.g

Force of Beauty or Object of Desire? The Priming Effects of Makeup Video Advertisements on Self-Objectification in College Women

Women are too often valued for their beauty and have shifted their focus from character to body improvement (Brumberg, 1998). Objectification theory (Frederickson & Roberts, 1997) posits that sexual objectification socializes females to evaluate themselves based on looks. Self-objectification is the attempt to control this external perception by monitoring one’s physical appearance. Women are more likely to think “How do I look?” than “What am I capable of?” The priming effects of positive and negative body-focused makeup advertisements on college-aged women’s level of self-objectification were examined in two separate studies. In study one, 87 participants viewing positive vs. negative advertisements reported more traits and abilities; this was especially true for high self-objectifiers. Participants viewing positive advertisements reported more positive emotions, suggesting the salutary role that positive messaging may play. Results were replicated in study two, with 172 participants who viewed positive vs. negative advertisements reporting significantly fewer body shape statements, more trait and abilities, as well as more physical competence statements. In addition, individuals who viewed advertisements with non-objectifying content responded with a significantly greater number of positively valenced statements and significantly fewer negative statements about themselves in comparison to women who viewed objectifying advertisements. These results suggest that marketers should eschew advertising that sexually objectifies women and promotes unattainable beauty goals. Future research should evaluate cumulative and long-term effects of advertisement and examine whether exposure that leads to lower levels of objectification also minimizes negative consequences associated with objectifying media influences (e.g., body shame, depression, eating disorder)

The Cross-Wavelet Transform and Analysis of Quasiperiodic Behavior in the Pearson-Readhead VLBI Survey Sources

We introduce an algorithm for applying a cross-wavelet transform to analysis of quasiperiodic variations in a time-series, and introduce significance tests for the technique. We apply a continuous wavelet transform and the cross-wavelet algorithm to the Pearson-Readhead VLBI survey sources using data obtained from the University of Michigan 26-m parabloid at observing frequencies of 14.5, 8.0, and 4.8 GHz. Thirty of the sixty-two sources were chosen to have sufficient data for analysis, having at least 100 data points for a given time-series. Of these thirty sources, a little more than half exhibited evidence for quasiperiodic behavior in at least one observing frequency, with a mean characteristic period of 2.4 yr and standard deviation of 1.3 yr. We find that out of the thirty sources, there were about four time scales for every ten time series, and about half of those sources showing quasiperiodic behavior repeated the behavior in at least one other observing frequency.Comment: Revised version, accepted by ApJ. 17 pages, 13 figures, color figures included as gifs, seperate from the text. The addition of statistical significance tests has resulted in modifying the technique and results, but the broad conclusion remain the same. A high resolution version may be found at http://www.astro.lsa.umich.edu/obs/radiotel/prcwdata.htm

In Situ Determination of Siderophile Trace Elements in Metals and Sulfides in Enstatite Achondrites

Enstatite meteorites are identified by their extremely reduced mineralogy (1) and similar oxygen isotope composition (2). The enstatite meteorite clan incorporates both EH and EL chondrites, as well as a wide variety of enstatite achondrites, such as aubrites or anomalous enstatite meteorites (e.g. Mt. Egerton, Shallowater, Zaklodzie, NWA 2526). The role of nebular versus planetary processes in the formation of enstatite meteorites is still under debate (e.g. 3-5). Past studies showed a significant influence of metal segregation in the formation of enstatite achondrites. Casanova et al. (6) suggested incomplete metal-silicate segregation during core formation and attributed the unfractionated siderophile element patterns in aubrites metals to a lack of fractional crystallization in a planetary core. Recent studies suggest a significant role of impact melting in the formation of primitive enstatite chondrites (7) and identified NWA 2526 as a partial melt residue of an enstatite chondrite (8). To understand the nature of siderophile element-bearing phases in enstatite achondrites, establish links between enstatite achondrites and enstatite chondrites (9), and constrain planetary differentiation on their respective parent bodies and their petrogenetic histories, we present laser ablation ICP-MS measurements of metal and sulfide phases in Shallowater, Mt. Egerton, and the aubrites Aubres, Cumberland Falls, and Mayo Belwa