Extraction of Airways with Probabilistic State-space Models and Bayesian Smoothing

Segmenting tree structures is common in several image processing applications. In medical image analysis, reliable segmentations of airways, vessels, neurons and other tree structures can enable important clinical applications. We present a framework for tracking tree structures comprising of elongated branches using probabilistic state-space models and Bayesian smoothing. Unlike most existing methods that proceed with sequential tracking of branches, we present an exploratory method, that is less sensitive to local anomalies in the data due to acquisition noise and/or interfering structures. The evolution of individual branches is modelled using a process model and the observed data is incorporated into the update step of the Bayesian smoother using a measurement model that is based on a multi-scale blob detector. Bayesian smoothing is performed using the RTS (Rauch-Tung-Striebel) smoother, which provides Gaussian density estimates of branch states at each tracking step. We select likely branch seed points automatically based on the response of the blob detection and track from all such seed points using the RTS smoother. We use covariance of the marginal posterior density estimated for each branch to discriminate false positive and true positive branches. The method is evaluated on 3D chest CT scans to track airways. We show that the presented method results in additional branches compared to a baseline method based on region growing on probability images.Comment: 10 pages. Pre-print of the paper accepted at Workshop on Graphs in Biomedical Image Analysis. MICCAI 2017. Quebec Cit

The potential of Antheraea pernyi silk for spinal cord repair

This work was supported by the Institute of Medical Sciences of the University of Aberdeen, Scottish Rugby Union and RS McDonald Charitable Trust. We are grateful to Mr Nicholas Hawkins from Oxford University and Ms Annette Raffan from the University of Aberdeen for assistance with tensile testing. We thank Ms Michelle Gniβ for her help with the microglial response experiments. We also thank Mr Gianluca Limodio for assisting with the MATLAB script for automation of tensile testing’s data analysis.Peer reviewedPublisher PD

Évaluation des habiletés de vie autonome chez les personnes psychotiques

Ce texte détaille les caractéristiques métrologiques de l'Échelle des habiletés de Vie Autonome (EHVA) mesurant les habiletés requises chez des personnes psychotiques, pour fonctionner de façon autonome au sein de la communauté. Ce questionnaire, qui comprend 65 items répartis en dix échelles d'habiletés, a été administré à 276 personnes psychotiques. Les résultats indiquent que, dans l'ensemble, la fidélité de cet instrument est bonne, mesurée par l'accord interjuges et les coefficients alpha. Trois des 10 échelles, soit les échelles Déplacement, Recherche d'emploi et Maintien de l'emploi, n'ont pu être conservées dans la version finale. Les quatre aspects de la validité examinés dans cette étude se révèlent très satisfaisants; il s'agit du degré de convergence entre l'évaluation faite par les participants eux-mêmes et par un membre du personnel soignant, des analyses discriminantes, des corrélations convergentes-divergentes avec d'autres instruments de mesure du fonctionnement psychosocial et de l'analyse factorielle exploratoire. Après ces analyses, la version finale de l'EHVA comprend 48 items répartis sous sept échelles. La discussion fait ressortir les qualités psychométriques d'un tel instrument en langue française et suggère des pistes de recherche pour poursuivre le développement de l'EHVA.This article studies in detail the metrological characteristics of the "Autonomous Life Skills Test" ("Echelle des Habiletés de Vie Autonome" or "EHVA") which measures the skills required of psychotic patients to function on their own in the community. The questionnaire, distributed to 276 psychotic patients, made use of 10 parameters of skills broken down into 65 items. Results show that, overall, this instrument is quite reliable, as measured by the inter-rater reliability and alpha coefficients. Three of the ten parameters, namely Mobility, Employment Search and Employment Holding, were not retained in the final version. The four validity aspects were found to be very satisfactory, namely the degree of convergence between the participant's self-evaluation and the evaluation provided by healthcare personnel, (discriminating analysis), convergent-divergent correlations with other instruments measuring psychosocial functioning and the exploratory factorial analysis. Following these analysis, the final version of the "EHVA" includes 48 items covering seven parameters. A discussion of results underscores the psychometric qualities of such a French-language instrument and suggests avenues to pursue the development of the "EHVA"

Coherence correlations in the dissipative two-state system

We study the dynamical equilibrium correlation function of the polaron-dressed tunneling operator in the dissipative two-state system. Unlike the position operator, this coherence operator acts in the full system-plus-reservoir space. We calculate the relevant modified influence functional and present the exact formal expression for the coherence correlations in the form of a series in the number of tunneling events. For an Ohmic spectral density with the particular damping strength $K=1/2$, the series is summed in analytic form for all times and for arbitrary values of temperature and bias. Using a diagrammatic approach, we find the long-time dynamics in the regime $K<1$. In general, the coherence correlations decay algebraically as $t^{-2K}$ at T=0. This implies that the linear static susceptibility diverges for $K\le 1/2$ as $T\to 0$, whereas it stays finite for $K>1/2$ in this limit. The qualitative differences with respect to the asymptotic behavior of the position correlations are explained.Comment: 19 pages, 4 figures, to be published in Phys. Rev.

Exact Friedel oscillations in the g=1/2 Luttinger liquid

A single impurity in the 1D Luttinger model creates a local modification of the charge density analogous to the Friedel oscillations. In this paper, we present an exact solution of the case $g={1\over 2}$ (the equivalent of the Toulouse point) at any temperature $T$ and impurity coupling, expressing the charge density in terms of a hypergeometric function. We find in particular that at $T=0$, the oscillatory part of the density goes as $\ln x$ at small distance and $x^{-1/2}$ at large distance.Comment: 1 reference added. 13 pages, harvma

Correlation functions of disorder operators in massive ghost theories

The two-dimensional ghost systems with negative integral central charge received much attention in the last years for their role in a number of applications and in connection with logarithmic conformal field theory. We consider the free massive bosonic and fermionic ghost systems and concentrate on the non-trivial sectors containing the disorder operators. A unified analysis of the correlation functions of such operators can be performed for ghosts and ordinary complex bosons and fermions. It turns out that these correlators depend only on the statistics although the scaling dimensions of the disorder operators change when going from the ordinary to the ghost case. As known from the study of the ordinary case, the bosonic and fermionic correlation functions are the inverse of each other and are exactly expressible through the solution of a non-linear differential equation.Comment: 8 pages, late

The long delayed solution of the Bukhvostov Lipatov model

In this paper I complete the solution of the Bukhvostov Lipatov model by computing the physical excitations and their factorized S matrix. I also explain the paradoxes which led in recent years to the suspicion that the model may not be integrable.Comment: 9 page

Green Function of the Sutherland Model with SU(2) internal symmetry

We obtain the hole propagator of the Sutherland model with SU(2) internal symmetry for coupling parameter $\beta=1$, which is the simplest nontrivial case. One created hole with spin down breaks into two quasiholes with spin down and one quasihole with spin up. While these elementary excitations are energetically free, the form factor reflects their anyonic character. The expression for arbitrary integer $\beta$ is conjectured.Comment: 13pages, Revtex, one ps figur

3D Geometric Analysis of Tubular Objects based on Surface Normal Accumulation

This paper proposes a simple and efficient method for the reconstruction and extraction of geometric parameters from 3D tubular objects. Our method constructs an image that accumulates surface normal information, then peaks within this image are located by tracking. Finally, the positions of these are optimized to lie precisely on the tubular shape centerline. This method is very versatile, and is able to process various input data types like full or partial mesh acquired from 3D laser scans, 3D height map or discrete volumetric images. The proposed algorithm is simple to implement, contains few parameters and can be computed in linear time with respect to the number of surface faces. Since the extracted tube centerline is accurate, we are able to decompose the tube into rectilinear parts and torus-like parts. This is done with a new linear time 3D torus detection algorithm, which follows the same principle of a previous work on 2D arc circle recognition. Detailed experiments show the versatility, accuracy and robustness of our new method.Comment: in 18th International Conference on Image Analysis and Processing, Sep 2015, Genova, Italy. 201

Hyperelliptic curves for multi-channel quantum wires and the multi-channel Kondo problem

We study the current in a multi-channel quantum wire and the magnetization in the multi-channel Kondo problem. We show that at zero temperature they can be written simply in terms of contour integrals over a (two-dimensional) hyperelliptic curve. This allows one to easily demonstrate the existence of weak-coupling to strong-coupling dualities. In the Kondo problem, the curve is the same for under- and over-screened cases; the only change is in the contour.Comment: 7 pages, 1 figure, revte