Process for preparing polyimide adhesives

High bonding strengths are obtained for metals and fiber-reinforced organic resin composites with no significant loss in thermo-oxidative stability of the adhesive resin

Spin-2 Amplitudes in Black-Hole Evaporation

Quantum amplitudes for $s=2$ gravitational-wave perturbations of Einstein/scalar collapse to a black hole are treated by analogy with $s=1$ Maxwell perturbations. The spin-2 perturbations split into parts with odd and even parity. We use the Regge-Wheeler gauge; at a certain point we make a gauge transformation to an asymptotically-flat gauge, such that the metric perturbations have the expected falloff behaviour at large radii. By analogy with $s=1$, for $s=2$ natural 'coordinate' variables are given by the magnetic part $H_{ij} (i,j=1,2,3)$ of the Weyl tensor, which can be taken as boundary data on a final space-like hypersurface $\Sigma_F$. For simplicity, we take the data on the initial surface $\Sigma_I$ to be exactly spherically-symmetric. The (large) Lorentzian proper-time interval between $\Sigma_I$ and $\Sigma_F$, measured at spatial infinity, is denoted by $T$. We follow Feynman's $+i\epsilon$ prescription and rotate $T$ into the complex: $T\to{\mid}T{\mid} \exp(-i\theta)$, for $0<\theta\leq\pi/2$. The corresponding complexified {\it classical} boundary-value problem is expected to be well-posed. The Lorentzian quantum amplitude is recovered by taking the limit as $\theta\to 0_+$. For boundary data well below the Planck scale, and for a locally supersymmetric theory, this involves only the semi-classical amplitude $\exp(iS^{(2)}_{\rm class}$, where $S^{(2)}_{\rm class}$ denotes the second-variation classical action. The relations between the $s=1$ and $s=2$ natural boundary data, involving supersymmetry, are investigated using 2-component spinor language in terms of the Maxwell field strength $\phi_{AB}=\phi_{(AB)}$ and the Weyl spinor $\Psi_{ABCD}=\Psi_{(ABCD)}$

Transition radiation by matter-wave solitons in optical lattices

We demonstrate that matter-wave solitary pulses formed from Bose condensed atoms moving inside optical lattices continuously radiate dispersive matter waves with prescribed momentum. Our analytical results for the radiation parameters and the soliton decay rate are found to be in excellent agreement with numerical modelling performed for experimentally relevant parameters.Comment: accepted to PR

Black hole evaporation in a spherically symmetric non-commutative space-time

Recent work in the literature has studied the quantum-mechanical decay of a Schwarzschild-like black hole, formed by gravitational collapse, into almost-flat space-time and weak radiation at a very late time. The relevant quantum amplitudes have been evaluated for bosonic and fermionic fields, showing that no information is lost in collapse to a black hole. On the other hand, recent developments in noncommutative geometry have shown that, in general relativity, the effects of non-commutativity can be taken into account by keeping the standard form of the Einstein tensor on the left-hand side of the field equations and introducing a modified energy-momentum tensor as a source on the right-hand side. Relying on the recently obtained non-commutativity effect on a static, spherically symmetric metric, we have considered from a new perspective the quantum amplitudes in black hole evaporation. The general relativity analysis of spin-2 amplitudes has been shown to be modified by a multiplicative factor F depending on a constant non-commutativity parameter and on the upper limit R of the radial coordinate. Limiting forms of F have been derived which are compatible with the adiabatic approximation.Comment: 8 pages, Latex file with IOP macros, prepared for the QFEXT07 Conference, Leipzig, September 200

Multi-Magnon Scattering in the Ferromagnetic XXX-Model with Inhomogeneities

We determine the transition amplitude for multi-magnon scattering induced through an inhomogeneous distribution of the coupling constant in the ferromagnetic XXX-model. The two and three particle amplitudes are explicitely calculated at small momenta. This suggests a rather plausible conjecture also for a formula of the general n-particle amplitude.Comment: 21 pages, latex, no figure

Structure of Mandelate Racemase with Bound Intermediate Analogues Benzohydroxamate and Cupferron

Mandelate racemase (MR, EC 5.1.2.2) from Pseudomonas putida catalyzes the Mg2+-dependent interconversion of the enantiomers of mandelate, stabilizing the altered substrate in the transition state by 26 kcal/mol relative to the substrate in the ground state. To understand the origins of this binding discrimination, we determined the X-ray crystal structures of wild-type MR complexed with two analogues of the putative aci-carboxylate intermediate, benzohydroxamate and Cupferron, to 2.2-Å resolution. Benzohydroxamate is shown to be a reasonable mimic of the transition state and/or intermediate because its binding affinity for 21 MR variants correlates well with changes in the free energy of transition state stabilization afforded by these variants. Both benzohydroxamate and Cupferron chelate the active site divalent metal ion and are bound in a conformation with the phenyl ring coplanar with the hydroxamate and diazeniumdiolate moieties, respectively. Structural overlays of MR complexed with benzohydroxamate, Cupferron, and the ground state analogue (S)-atrolactate reveal that the para carbon of the substrate phenyl ring moves by 0.8−1.2 Å between the ground state and intermediate state, consistent with the proposal that the phenyl ring moves during MR catalysis while the polar groups remain relatively fixed. Although the overall protein structure of MR with bound intermediate analogues is very similar to that of MR with bound (S)-atrolactate, the intermediate−Mg2+ distance becomes shorter, suggesting a tighter complex with the catalytic Mg2+. In addition, Tyr 54 moves closer to the phenyl ring of the bound intermediate analogues, contributing to an overall constriction of the active site cavity. However, site-directed mutagenesis experiments revealed that the role of Tyr 54 in MR catalysis is relatively minor, suggesting that alterations in enzyme structure that contribute to discrimination between the altered substrate in the transition state and the ground state by this proficient enzyme are extremely subtle

Paraoxonase gene polymorphisms and haplotype analysis in a stroke population

Peer reviewedPublisher PD

Study of resonance light scattering for remote optical probing

Enhanced scattering and fluorescence processes in the visible and UV were investigated which will enable improved remote measurements of gas properties. The theoretical relationship between scattering and fluorescence from an isolated molecule in the approach to resonance is examined through analysis of the time dependence of re-emitted light following excitation of pulsed incident light. Quantitative estimates are developed for the relative and absolute intensities of fluorescence and resonance scattering. New results are obtained for depolarization of scattering excited by light at wavelengths within a dissociative continuum. The experimental work was performed in two separate facilities. One of these utilizes argon and krypton lasers, single moded by a tilted etalon, and a 3/4 meter double monochromator. This facility was used to determine properties of the re-emission from NO2, I2 and O3 excited by visible light. The second facility involves a narrow-line dye laser, and a 3/4 meter single monochromator. The dye laser produces pulsed light with 5 nsec pulse duration and 0.005 nm spectral width

Inducible arginase 1 deficiency in mice leads to hyperargininemia and altered amino acid metabolism

Arginase deficiency is a rare autosomal recessive disorder resulting from a loss of the liver arginase isoform, arginase 1 (ARG1), which is the final step in the urea cycle for detoxifying ammonia. ARG1 deficiency leads to hyperargininemia, characterized by progressive neurological impairment, persistent growth retardation and infrequent episodes of hyperammonemia. Using the Cre/loxP-directed conditional gene knockout system, we generated an inducible Arg1-deficient mouse model by crossing "floxed" Arg1 mice with CreER(T2) mice. The resulting mice (Arg-Cre) die about two weeks after tamoxifen administration regardless of the starting age of inducing the knockout. These treated mice were nearly devoid of Arg1 mRNA, protein and liver arginase activity, and exhibited symptoms of hyperammonemia. Plasma amino acid analysis revealed pronounced hyperargininemia and significant alterations in amino acid and guanidino compound metabolism, including increased citrulline and guanidinoacetic acid. Despite no alteration in ornithine levels, concentrations of other amino acids such as proline and the branched-chain amino acids were reduced. In summary, we have generated and characterized an inducible Arg1-deficient mouse model exhibiting several pathologic manifestations of hyperargininemia. This model should prove useful for exploring potential treatment options of ARG1 deficiency

Gravitational amplitudes in black-hole evaporation: the effect of non-commutative geometry

Recent work in the literature has studied the quantum-mechanical decay of a Schwarzschild-like black hole, formed by gravitational collapse, into almost-flat space-time and weak radiation at a very late time. The relevant quantum amplitudes have been evaluated for bosonic and fermionic fields, showing that no information is lost in collapse to a black hole. On the other hand, recent developments in noncommutative geometry have shown that, in general relativity, the effects of noncommutativity can be taken into account by keeping the standard form of the Einstein tensor on the left-hand side of the field equations and introducing a modified energy-momentum tensor as a source on the right-hand side. The present paper, relying on the recently obtained noncommutativity effect on a static, spherically symmetric metric, considers from a new perspective the quantum amplitudes in black hole evaporation. The general relativity analysis of spin-2 amplitudes is shown to be modified by a multiplicative factor F depending on a constant non-commutativity parameter and on the upper limit R of the radial coordinate. Limiting forms of F are derived which are compatible with the adiabatic approximation here exploited. Approximate formulae for the particle emission rate are also obtained within this framework.Comment: 14 pages, 2 figures, Latex macros. In the final version, section 5 has been amended, the presentation has been improved, and References 21-24 have been added. Last misprints amended in Section 5 and Ref. 2