Active dynamic signage system: A full-scale evacuation trial

Efficient evacuation from transport terminals in an emergency can be constrained by the complex nature of the buildings. Although emergency signage systems are widely used as a well established means of facilitating evacuation, recent research demonstrates that only 38% of people 'see' conventional static emergency signage in simulated emergency situations. Besides, conventional signage only conveys single and passive information; therefore, they cannot be adapted to respond to developing evacuation situations. The EU FP7 GETWAY project addresses this problem for transport terminals through the development of an Intelligent Active Dynamic Signage System (IADSS), which routes terminal passengers to their optimal exit according to the distribution of occupants and the nature of the evolving incident. This paper presents the results of two full scale evacuation trials conducted in a rail station to establish the specific benefits of the Active Dynamic Signage System (i.e. ADSS, a subsystem of the IADSS without the intelligent component) over the current standard emergency signage system. These trials demonstrate that the flashing lights of the ADSS do have a greater effect on route choice compared to the standard signage system and therefore are more likely to promote the adoption of emergency evacuation procedures than would otherwise be the case, especially where evacuees are required to adopt routes not entirely based on proximity

Development of a new laser Doppler velocimeter for the Ames High Reynolds Channel No. 2

A new two-channel laser Doppler velocimeter developed for the Ames High Reynolds Channel No. 2 is described. Design features required for the satisfactory operation of the optical system in the channel environment are discussed. Fiber optics are used to transmit the megahertz Doppler signal to the photodetectors located outside the channel pressure vessel, and provision is made to isolate the optical system from pressure and thermal strain effects. Computer-controlled scanning mirrors are used to position the laser beams in the channel flow. Techniques used to seed the flow with 0.5-micron-diam polystyrene spheres avoiding deposition on the test-section windows and porous boundary-layer removal panels are described. Preliminary results are presented with a discussion of several of the factors affecting accuracy

Joint system quantum descriptions arising from local quantumness

Bipartite correlations generated by non-signalling physical systems that admit a finite-dimensional local quantum description cannot exceed the quantum limits, i.e., they can always be interpreted as distant measurements of a bipartite quantum state. Here we consider the effect of dropping the assumption of finite dimensionality. Remarkably, we find that the same result holds provided that we relax the tensor structure of space-like separated measurements to mere commutativity. We argue why an extension of this result to tensor representations seems unlikely

Two approaches to testing general relativity in the strong-field regime

Observations of compact objects in the electromagnetic spectrum and the detection of gravitational waves from them can lead to quantitative tests of the theory of general relativity in the strong-field regime following two very different approaches. In the first approach, the general relativistic field equations are modified at a fundamental level and the magnitudes of the potential deviations are constrained by comparison with observations. In the second approach, the exterior spacetimes of compact objects are parametrized in a phenomenological way, the various parameters are measured observationally, and the results are finally compared against the general relativistic predictions. In this article, I discuss the current status of both approaches, focusing on the lessons learned from a large number of recent investigations.Comment: To appear in the proceedings of the conference New Developments in Gravit

Construction site evacuation safety: Evacuation strategies for tall construction sites: Research summary

What’s the problem? The soaring scale of high-rise building construction – the number of projects and the size of the buildings – is reflected in the number of workers exposed to these demanding construction environments and the need for large-scale evacuation. In London alone, an estimated 541 high-rise building projects were planned as of the end of 2018. While fire is not a major cause of death or injury on UK construction sites, given the high frequency of fires and the number of workers involved, there is nevertheless a significant risk to the health and safety of workers if an emergency evacuation caused by fire or other on-site emergency is required. It is therefore essential that large-scale construction sites have robust plans for safe and timely emergency evacuation. The overall aim of the project is to improve the safety of construction site workers during on-site emergency evacuation, through the development of a unique evidence base characterising, for the first time, the actual performance and behaviour of construction workers during emergency evacuation. Combining this information with computer simulation will inform the development of more reliable evacuation procedures, improving the work environment through better preparation for, and management of, on-site emergency evacuation, and advancing the safety of construction workers

Construction site evacuation safety: Evacuation strategies for tall construction sites: Research report

BACKGROUND: The soaring scale of high-rise building construction – the number of projects and the size of the buildings – is reflected in the number of workers exposed to these demanding construction environments, and the potential for large-scale evacuation. In London alone, an estimated 541 highrise building projects are planned for the next few years. A typical project, such as the ￡400 million ‘100 Bishopsgate’ building, will have a peak of around 1,500 workers on site, and a cumulative workforce estimated at 12,000. The total number of workers exposed to construction sites in London during the lifetime of these 541 construction projects could easily exceed three million people. AIMS: The overall aim of the project is to improve the safety of construction site workers during on-site emergency evacuation, through the development of a unique evidence base characterising, for the first time, the actual performance and behaviour of construction workers during emergency evacuation. Combining this information with computer simulation will inform the development of more reliable evacuation procedures, improving the work environment through better preparation for, and management of, on-site emergency evacuation, and advancing the safety of construction workers. METHODOLOGY: The project consisted of four full-scale evacuation trials of two different high-rise buildings at two stages of construction, and five walking speed experiments. In total, 1,078 participants were involved in the nine trials, generating a data-set of around 2,200 data points, and information from 61 worker questionnaires. Analysis of this data produced generalised distributions for response times, walking speeds, stair speeds and ladder speeds, which were used to calibrate and validate the buildingEXODUS evacuation model. The validated model was then used to run 1,900 simulations exploring the impact on evacuation efficiency of changes to occupant response time, replacing formwork ladders with temporary stairs, and the use of hoists for evacuation. RESULTS: 31 key findings from this analysis were produced: • questionnaire analysis – eight key findings • generalised response time (RT) analysis relating to the formworks – five key findings • generalised RT analysis relating to the main building – three key findings • generalised climbing/walking speeds on ladders, temporary stairs and floor surfaces – four key findings • validation analysis – four key findings • use of the validated evacuation model to explore improvements in evacuation performance – seven key findings. CONCLUSIONS: The project has developed a unique evidence base characterising, for the first time, the actual performance and behaviour of construction workers during emergency evacuation. It consists of (i) response times for workers in the main building and the formworks, as measured from the sounding of the alarm in the main building, (ii) worker walking speeds on different types of surfaces, such as concrete, decking and decking with rebar, and (iii) worker ascent and descent speeds on temporary dogleg and parallel scaffold stairs and ladders. The data has been incorporated in the building evacuation simulation tool buildingEXODUS, providing it with a unique capability to simulate evacuation from high-rise construction sites. The performance of the software has been validated using measured data collected from the trials. The validated software has been used to explore how evacuation procedures for high-rise construction sites can be improved, including the impact of reducing worker response times, replacing ladders with temporary scaffold stairs within the formworks, and using hoists to assist in evacuation

Y2Y4 Receptor Double Knockout Protects Against Obesity Due to a High-Fat Diet or Y1 Receptor Deficiency in Mice

Neuropeptide Y receptors are critical regulators of energy homeostasis, but the functional interactions and relative contributions of Y receptors and the environment in this process are unknown. We measured the effects of an ad libitum diet of normal or high-fat food on energy balance in mice with single, double, or triple deficiencies of Y1, Y2, or Y4 receptors. Whereas wild-type mice developed diet-induced obesity, Y2Y4 double knockouts did not. In contrast, Y1 knockout or Y1Y2 or Y1Y4 receptor double knockout mice developed an exacerbated diet-induced obesity syndrome. Remarkably, the antiobesity effect of Y2Y4 deficiency was stronger than the obesogenic effect of Y1 deficiency, since Y1Y2Y4 triple knockouts did not develop obesity on the high-fat diet. Resistance to diet-induced obesity in Y2Y4 knockouts was associated with reduced food intake and improved glucose tolerance in the absence of changes in total physical activity. Fecal concentration of free fatty acids was significantly increased in Y2Y4 knockouts in association with a significantly reduced bile acid pool and marked alterations in intestinal morphology. In addition, hypothalamic proopiomelanocortin expression was decreased in diet-induced obesity (in both wild-type and Y1 receptor knockout mice) but not in obesity-resistant Y2Y4 receptor knockout mice fed a high-fat diet. Therefore, deletion of Y2 and Y4 receptors synergistically protects against diet-induced obesity, at least partially via changes in food intake and hypothalamic proopiomelanocortin expression

A Randomized Trial of Nighttime Physician Staffing in an Intensive Care Unit

Background Increasing numbers of intensive care units (ICUs) are adopting the practice of nighttime intensivist staffing despite the lack of experimental evidence of its effectiveness. Methods We conducted a 1-year randomized trial in an academic medical ICU of the effects of nighttime staffing with in-hospital intensivists (intervention) as compared with nighttime coverage by daytime intensivists who were available for consultation by telephone (control). We randomly assigned blocks of 7 consecutive nights to the intervention or the control strategy. The primary outcome was patients’ length of stay in the ICU. Secondary outcomes were patients’ length of stay in the hospital, ICU and in-hospital mortality, discharge disposition, and rates of readmission to the ICU. For length-of-stay outcomes, we performed time-to-event analyses, with data censored at the time of a patient’s death or transfer to another ICU. Results A total of 1598 patients were included in the analyses. The median Acute Physiology and Chronic Health Evaluation (APACHE) III score (in which scores range from 0 to 299, with higher scores indicating more severe illness) was 67 (interquartile range, 47 to 91), the median length of stay in the ICU was 52.7 hours (interquartile range, 29.0 to 113.4), and mortality in the ICU was 18%. Patients who were admitted on intervention days were exposed to nighttime intensivists on more nights than were patients admitted on control days (median, 100% of nights [interquartile range, 67 to 100] vs. median, 0% [interquartile range, 0 to 33]; P\u3c0.001). Nonetheless, intensivist staffing on the night of admission did not have a significant effect on the length of stay in the ICU (rate ratio for the time to ICU discharge, 0.98; 95% confidence interval [CI], 0.88 to 1.09; P=0.72), ICU mortality (relative risk, 1.07; 95% CI, 0.90 to 1.28), or any other end point. Analyses restricted to patients who were admitted at night showed similar results, as did sensitivity analyses that used different definitions of exposure and outcome. Conclusions In an academic medical ICU in the United States, nighttime in-hospital intensivist staffing did not improve patient outcomes. (Funded by University of Pennsylvania Health System and others; ClinicalTrials.gov number, NCT01434823.

Climate vulnerability assessment for Pacific salmon and steelhead in the California Current Large Marine Ecosystem.

Major ecological realignments are already occurring in response to climate change. To be successful, conservation strategies now need to account for geographical patterns in traits sensitive to climate change, as well as climate threats to species-level diversity. As part of an effort to provide such information, we conducted a climate vulnerability assessment that included all anadromous Pacific salmon and steelhead (Oncorhynchus spp.) population units listed under the U.S. Endangered Species Act. Using an expert-based scoring system, we ranked 20 attributes for the 28 listed units and 5 additional units. Attributes captured biological sensitivity, or the strength of linkages between each listing unit and the present climate; climate exposure, or the magnitude of projected change in local environmental conditions; and adaptive capacity, or the ability to modify phenotypes to cope with new climatic conditions. Each listing unit was then assigned one of four vulnerability categories. Units ranked most vulnerable overall were Chinook (O. tshawytscha) in the California Central Valley, coho (O. kisutch) in California and southern Oregon, sockeye (O. nerka) in the Snake River Basin, and spring-run Chinook in the interior Columbia and Willamette River Basins. We identified units with similar vulnerability profiles using a hierarchical cluster analysis. Life history characteristics, especially freshwater and estuary residence times, interplayed with gradations in exposure from south to north and from coastal to interior regions to generate landscape-level patterns within each species. Nearly all listing units faced high exposures to projected increases in stream temperature, sea surface temperature, and ocean acidification, but other aspects of exposure peaked in particular regions. Anthropogenic factors, especially migration barriers, habitat degradation, and hatchery influence, have reduced the adaptive capacity of most steelhead and salmon populations. Enhancing adaptive capacity is essential to mitigate for the increasing threat of climate change. Collectively, these results provide a framework to support recovery planning that considers climate impacts on the majority of West Coast anadromous salmonids