In vitro antiproliferative activities and kinases inhibitory potencies of glycosyl-isoindigo derivatives

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Synthesis, in vitro kinase inhibitory potencies and antibacterial evaluation of diversely substituted indolin-2-ones

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Ink bleed-through removal of historical manuscripts based on hyperspectral imaging

Old manuscripts can be degraded by different reasons over time. The ink bleed-through from the back side of the page is a common problem which compromises the readability and the aesthetics of the document. Unsupervised bleed-through removal is a challenging task as pixel intensity of bleed-through areas can be very similar to fine-details of the writing. This paper provides a brief review about state-of-the-art methods for bleed-through removal. Moreover, we propose an algorithm for the segmentation of the bleed-through areas from a manuscript collected from the National Library of Oslo using hyperspectral imaging. This work also presents the restoration of the collected manuscript applying inpainting algorithms based on our segmentation approach

An overview of the CATE algorithms for real-time pitch determination

International audienceIn this paper, we present a recent algorithm for pitch detection based on an implicit circular autocorrelation of the glottal excitation signal. This algorithm operates in real time without the use of any post-processing technique. This article focuses on the correction of the pitch contours estimated and on the reduction in classification errors in speech signals using simple voicing decision techniques. To evaluate the performance of our algorithms, we used the Bagshaw and Keele databases. We show in this study that the sum of the percentage of the unvoiced errors and the percentage of the voiced errors, for the male Bagshaw corpus, reaches a very good score of 14.67. For the female corpus, our results are also competitive compared to other algorithms using the same database. Concerning the Keele database, we succeed to obtain very good gross pitch error, voicing decision error and F0 frame error rates, respectively, 0.44, 0.65 and 1.55 % in the whole corpus

Enhancing the Autonomy of Disabled Persons: Assistive Technologies Directed by User Feedback

Europe faces a major and growing healthcare problem due to increase in population, increasing longevity and an aging population with disability. Such dependent, elderly, disabled and vulnerable persons, are concerned since they wish to live at home as long as possible. This aspiration is also shared by national policies and communities across EU. To ensure the optimum care of dependent people, innovative solutions are encouraged to maintain independent life style. This paper outlines two projects, SYSIASS and COALAS, which aim to develop a set of technology based solutions to meet the needs and empower these people by enhancing mobility and communication