1,026 research outputs found

    Towards a synthesized critique of neoliberal biodiversity conservation

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    During the last three decades, the arena of biodiversity conservation has largely aligned itself with the globally dominant political ideology of neoliberalism and associated governmentalities. Schemes such as payments for ecological services are promoted to reach the multiple ‘wins’ so desired: improved biodiversity conservation, economic development, (international) cooperation and poverty alleviation, amongst others. While critical scholarship with respect to understanding the linkages between neoliberalism, capitalism and the environment has a long tradition, a synthesized critique of neoliberal conservation - the ideology (and related practices) that the salvation of nature requires capitalist expansion - remains lacking. This paper aims to provide such a critique. We commence with the assertion that there has been a conflation between ‘economics’ and neoliberal ideology in conservation thinking and implementation. As a result, we argue, it becomes easier to distinguish the main problems that neoliberal win-win models pose for biodiversity conservation. These are framed around three points: the stimulation of contradictions; appropriation and misrepresentation and the disciplining of dissent. Inspired by Bruno Latour’s recent ‘compositionist manifesto’, the conclusion outlines some ideas for moving beyond critique

    Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGF(delta/delta) mouse model of amyotrophic lateral sclerosis

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    Background: Vascular endothelial growth factor (VEGF) is an endothelial cell mitogen that stimulates vasculogenesis. It has also been shown to act as a neurotrophic factor in vitro and in vivo. Deletion of the hypoxia response element of the promoter region of the gene encoding VEGF in mice causes a reduction in neural VEGF expression, and results in adult-onset motor neurone degeneration that resembles amyotrophic lateral sclerosis (ALS). Investigating the molecular pathways to neurodegeneration in the VEGF(delta/delta) mouse model of ALS may improve understanding of the mechanisms of motor neurone death in the human disease. Results: Microarray analysis was used to determine the transcriptional profile of laser captured spinal motor neurones of transgenic and wild-type littermates at 3 time points of disease. 324 genes were significantly differentially expressed in motor neurones of presymptomatic VEGF(delta/delta) mice, 382 at disease onset, and 689 at late stage disease. Massive transcriptional downregulation occurred with disease progression, associated with downregulation of genes involved in RNA processing at late stage disease. VEGF(delta/delta) mice showed reduction in expression, from symptom onset, of the cholesterol synthesis pathway, and genes involved in nervous system development, including axonogenesis, synapse formation, growth factor signalling pathways, cell adhesion and microtubule-based processes. These changes may reflect a reduced capacity of VEGF(delta/delta) mice for maintenance and remodelling of neuronal processes in the face of demands of neural plasticity. The findings are supported by the demonstration that in primary motor neurone cultures from VEGF(delta/delta) mice, axon outgrowth is significantly reduced compared to wild-type littermates. Conclusions: Downregulation of these genes involved in axon outgrowth and synapse formation in adult mice suggests a hitherto unrecognized role of VEGF in the maintenance of neuronal circuitry. Dysregulation of VEGF may lead to neurodegeneration through synaptic regression and dying-back axonopathy

    Experimental characterization of railgun-driven supersonic plasma jets motivated by high energy density physics applications

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    We report experimental results on the parameters, structure, and evolution of high-Mach-number (M) argon plasma jets formed and launched by a pulsed-power-driven railgun. The nominal initial average jet parameters in the data set analyzed are density \approx 2 x 10^(16) cm^(-3), electron temperature \approx 1.4 eV, velocity \approx 30 km/s, M \approx 14, ionization fraction \approx 0.96, diameter \approx 5 cm, and length \approx 20 cm. These values approach the range needed by the Plasma Liner Experiment (PLX), which is designed to use merging plasma jets to form imploding spherical plasma liners that can reach peak pressures of 0.1-1 Mbar at stagnation. As these jets propagate a distance of approximately 40 cm, the average density drops by one order of magnitude, which is at the very low end of the 8-160 times drop predicted by ideal hydrodynamic theory of a constant-M jet.Comment: 35 pages, 2 tables, 14 figures, accepted for publication in Physics of Plasmas (12/11/2012

    Inter-sectoral and multilevel coordination alone do not reduce deforestation and advance environmental justice:Why bold contestation works when collaboration fails

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    Policy makers, academics, and conservationists often posit that poor coordination between different land use sectors, and between levels of governance, as an underlying challenge for reducing deforestation and forest degradation. This paper analyzes this argument using data from interviews with over 500 respondents from government, nongovernmental organizations, private companies, local and indigenous communities, activists, and individuals involved in 35 diverse land use initiatives in three countries: Peru, Indonesia, and Mexico. We find that while there is strong evidence of widespread coordination failures between sectors and levels, more fundamental political issues preclude effective coordination. We argue that political coalitions act to oppose environmental objectives and to impede their opponents from participating in land use governance. Moreover, we find that where coordination between actors does occur, it does not necessarily produce environmentally sustainable and socially just land use outcomes. Where we do find successful initiatives to reduce deforestation and benefit local people, effective coordination between well-informed actors is often present, but it does not occur spontaneously, and is instead driven by political organizing over time by activists, local people, nongovernmental organizations, and international donors. We suggest that the global environmental community must recognize explicitly these political dimensions of land use governance in order to successfully collaborate with local people to reduce deforestation
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