THE 2003 SUPERMARKET PANEL ANNUAL REPORT

Executive Summary The Food Industry Center established the Supermarket Panel in 1998 as the basis for an ongoing study of the supermarket industry. Since 2000 the core of the Panel has been a random sample of stores drawn from the approximately 32,000 supermarkets in the U.S. that accept food stamps. The purpose of collecting data on supermarket operations and performance is to: Provide timely, useful information for the industry through benchmark reports and annual summaries, trends on key indices of technology adoption, competitive positions and performance. Be a ready source of data for research on current and emerging issues - to be able to track the changes in operation and its impacts on performance over time. This report presents findings from the 2003 Supermarket Panel, and provides an overview of findings from the past four years. The 2003 Panel includes 391 stores that are a representative cross-section of the supermarket industry. The Panel tries to follow the same stores over time. Of the 391 stores, 268 were in the Panel in 2002. Nine percent of the stores have been in the Panel all four years. At least one store from every state is in the Panel. New in 2003 The Panel was offered over the Internet. Forty-seven percent responded on-line. An index on variety offering was created. Questions about offering irradiated fresh ground beef are included (with a follow up study). Supply Chain Technology Practices The Supply Chain Score measures the extent to which stores have adopted computerized methods of communicating with suppliers, handling inventory management, ordering, invoicing, and analyzing consumer purchases. The average score has almost doubled in four years. Stores in groups (chains) with more than 750 stores and/or supercenter formats have adopted supply chain practices most intensively. Internet/Intranet is used by at least two-thirds of all stores; over ninety percent of stores in groups with more than 50 stores use this technology. Vendor managed inventory has been adopted by only 42 percent of stores in the biggest store groups with much lower rates of adoption in smaller store groups. A higher Supply Chain Score benefited significantly higher sales per labor hour. Service and Variety Scores About eighty percent of stores in all size groups offer bagging and custom meat cutting. Variety pays off in better performance for five out of eight measures. Variety helps to grow annual percentage sales. Supercenters/Top Stores/Unions Supercenters have significantly higher sales per labor hour and per transaction. They have lower sales growth. Fifty-three percent of supermarkets face supercenter competition. They have somewhat higher sales per square foot of selling area and higher annual sales growth than stores that do not face supercenter competition. Eleven percent of stores in the 2003 Panel qualified as "top stores." They had above the median levels for each of three performance measures: weekly sales per square foot, sales per labor hour, and annual percentage sales growth. Top stores are more likely to have a unionized labor force, be a price and variety leader, and be wholesaler supplied. One-third of 2003 Panel stores have unionized labor. These stores have more productive labor with significantly higher sales per labor hour. Statistically Significant Drivers of Performance Over Time The descriptive profile and analysis of the Panel provide useful insights on the structure of the supermarket industry and factors associated with strong performance. However, statistical regression analysis identifies whether a variable is significantly correlated with a performance measure holding all else constant. This section presents findings from a multivariate regression analysis of five key performance measures. These regression analyses are summarized on the table below. If a characteristic is listed on the table it was a significant correlate in at least three out of the past four years. For example, in the last row, the only variable that was consistently significant for increasing annual percentage sales growth is being in an area with higher household incomes. Having a warehouse format decreased sales growth and three other factors were significant in at least three years but alternated with positive and negative effects.Industrial Organization, Marketing,

Effects of fibre content and textile structure on dynamic-mechanical and shape-memory properties of ELO/flax biocomposites

Biocomposites were prepared using epoxidized linseed oil (ELO) and flax fibre reinforcements in different assemblies. ELO was cured by two different anhydrides to check how its thermomechanical properties can be influenced. As reinforcements nonwoven mat, twill weave and quasi-unidirectional textile fabrics with two different yarn finenesses were used. Their reinforcing effect was determined in dynamic mechanical analysis (DMA) in flexure. DMA served also to determine the glass transition temperature (Tg). Shape memory properties were derived from quasiunconstrained flexural tests performed near to the Tg of the ELO and its biocomposites. Flax reinforcement reduced the Tg that was attributed to off-stoichiometry owing to chemical reaction between the hydroxyl groups of flax and anhydride hardener. The shape memory parameters were moderate or low. They were affected by both textile content and type

3D printing of twisting and rotational bistable structures with tuning elements

Three-dimensional (3D) printing is ideal for the fabrication of various customized 3D components with fine details and material-design complexities. However, most components fabricated so far have been static structures with fixed shapes and functions. Here we introduce bistability to 3D printing to realize highly-controlled, reconfigurable structures. Particularly, we demonstrate 3D printing of twisting and rotational bistable structures. To this end, we have introduced special joints to construct twisting and rotational structures without post-assembly. Bistability produces a well-defined energy diagram, which is important for precise motion control and reconfigurable structures. Therefore, these bistable structures can be useful for simplified motion control in actuators or for mechanical switches. Moreover, we demonstrate tunable bistable components exploiting shape memory polymers. We can readjust the bistability-energy diagram (barrier height, slope, displacement, symmetry) after printing and achieve tunable bistability. This tunability can significantly increase the use of bistable structures in various 3D-printed components

Simple models for the heat flux from the Atlantic meridional overturning cell to the atmosphere

It has been suggested that a slowdown of the Atlantic meridional overturning cell (AMOC) would cause the Northern Hemisphere to cool by a few degrees. We use a sequence of simple analytical models to show that due to the nonlinearity of the system, the simplified heat flux from the modeled AMOC to the atmosphere above is so robust that even changes of as much as 50% in the present AMOC transport are not enough to significantly change the temperature of the outgoing warmed atmosphere (i.e., the fraction of the atmosphere warmed by the AMOC). Our most realistic model (which is still a far cry from reality) involves a warm ocean losing heat to an otherwise motionless and colder atmosphere. As a result, the compressible atmosphere convects, and the generated airflow ultimately penetrates horizontally into the surrounding air. The behavior of the system is attributable to four key aspects of the underlying physical processes: (1) convective atmospheric transport increases by warming the atmosphere, (2) the ocean is warmer than the atmosphere, (3) the surface heat flux is usually proportional to the temperature difference between the ocean and the atmosphere, and (4) the specific heat capacity of water is much larger than that of the air. Taken together, these properties of the system lead to the existence of a dynamic “asymptotic” state, a modeled regime, in which even significant changes in the AMOC transport have almost no effect on the ocean-atmosphere heat flux and the resulting outgoing atmospheric temperature. In the hypothetical limit of an infinitely large specific heat capacity of water, Cpw there is no change in either the atmospheric transport or the temperatures of the ocean and the atmosphere, regardless of how large the reduction in the AMOC transport is. Although our models may be too simple to allow for a direct application to the ocean and atmosphere, they do shed light on the processes in question

The Role of Family-led Disability Organizations in Supporting Families with Hearing-Related Concerns

A survey was conducted with state level chapters from Family Voices, Parent Training and Information Centers, and Parent–to-Parent USA to understand their current activities support families of children with hearing-related concerns and to identify gaps in their ability to support families of children who are D/HH. these organizations reported that they are contacted with parent requests for information in regard to family support opportunities, early intervention, referral sources pertaining to hearing concerns, financial help, and providing information about legal rights. Results showed that the greatest challenges for these organizations were related to needing to connect families to financial resources pertaining to hearing-related needs, engaging families of children who are deaf/hard of hearing in their organization\u27s activities, having resources available in other languages, and 4) identifying pediatric providers that serve D/HH children. Potential ways to strengthen the capacity of these organizations to meet the needs of families with hearing-related concerns as well as increasing their awareness of partnerships with the EHDI system are discussed

Efficient derivation of NPCs, spinal motor neurons and midbrain dopaminergic neurons from hESCs at 3% oxygen

This protocol has been designed to generate neural precursor cells (NPCs) from human embryonic stem cells (hESCs) using a physiological oxygen (O(2)) level of 3% and chemically defined conditions. The first stage involves suspension culture of hESC colonies at 3% O(2), where they acquire a neuroepithelial identity over two weeks. This timescale is comparable to that at 20% O(2), but survival is enhanced. Sequential application of retinoic acid (RA) and purmorphamine (PM), from day 14 to 28, directs differentiation towards spinal motor neurons. Alternatively, addition of FGF-8 and PM generates midbrain dopaminergic neurons. OLIG2 induction in motor neuron precursors is 2-fold greater than at 20% O(2), whereas EN1 is 5-fold enhanced. 3% NPCs can be differentiated into all three neural lineages, and such cultures can be maintained long-term in the absence of neurotrophins. The ability to generate defined cell types at 3% O(2) should represent a significant advance for in vitro disease modelling and potentially cell-based therapies

Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation

Prova tipográfica (In Press)An important question arising from previous observations in vivo is whether glucocorticoids can directly influence neuronal survival in the hippocampus. To this end, a primary postnatal hippocampal culture system containing mature neurons and expressing both glucocorticoid (GR) and mineralocorticoid (MR) receptors was developed. Results show that the GR agonist dexamethasone (DEX) targets neurons (microtubule-associated protein 2-positive cells) for death through apoptosis. GR-mediated cell death was counteracted by the MR agonist aldosterone (ALDO). Antagonism of MR with spironolactone ([7a-(acetylthio)-3-oxo-17a-pregn- 4-ene,21 carbolactone] (SPIRO)) causes a dose-dependent increase in neuronal apoptosis in the absence of DEX, indicating that nanomolar levels of corticosterone present in the culture medium, which are sufficient to activate MR, can mask the apoptotic response to DEX. Indeed, both SPIRO and another MR antagonist, oxprenoate potassium ((7a,17a)-17-Hydroxy-3-oxo-7- propylpregn-4-ene-21-carboxylic acid, potassium salt (RU28318)), accentuated DEX-induced apoptosis. These results demonstrate that GRs can act directly to induce hippocampal neuronal death and that demonstration of their full apoptotic potency depends on abolition of survival-promoting actions mediated by MR

Screening For Neurotoxic Potential Of 15 Flame Retardants Using Freshwater Planarians

Asexual freshwater planarians are an attractive invertebrate model for high-throughput neurotoxicity screening, because they possess multiple quantifiable behaviors to assess distinct neuronal functions. Planarians uniquely allow direct comparisons between developing and adult animals to distinguish developmentally selective effects from general neurotoxicity. In this study, we used our automated planarian screening platform to compare the neurotoxicity of 15 flame retardants (FRs), consisting of representative phased-out brominated (BFRs) and replacement organophosphorus FRs (OPFRs). OPFRs have emerged as a proposed safer alternative to BFRs; however, limited information is available on their health effects. We found 11 of the 15 FRs (3/6 BFRs, 7/8 OPFRs, and Firemaster 550) caused adverse effects in both adult and developing planarians with similar nominal lowest-effect-levels for BFRs and OPFRs. This suggests that replacement OPFRs are comparably neurotoxic to the phased-out compounds. BFRs were primarily systemically toxic, whereas OPFRs, except Tris(2-chloroethyl) phosphate, shared a behavioral phenotype in response to noxious heat at sublethal concentrations, indicating specific neurotoxic effects. We found this behavioral phenotype was correlated with cholinesterase inhibition, thus linking behavioral outcomes to molecular targets. By directly comparing effects on adult and developing planarians, we further found that one BFR (3,3′,5,5′-Tetrabromobisphenol A) caused a developmental selective defect. Together, these results demonstrate that our planarian screening platform yields high content data from various behavioral and morphological endpoints, allowing us to distinguish selective neurotoxic effects and effects specific to the developing nervous system. Ten of these 11 bioactive FRs were previously found to be bioactive in other models, including cell culture and alternative animal models (nematodes and zebrafish). This level of concordance across different platforms emphasizes the urgent need for further evaluation of OPFRs in mammalian systems

Determination of nutrient salts by automatic methods both in seawater and brackish water: the phosphate blank

9 páginas, 2 tablas, 2 figurasThe main inconvenience in determining nutrients in seawater by automatic methods is simply solved: the preparation of a suitable blank which corrects the effect of the refractive index change on the recorded signal. Two procedures are proposed, one physical (a simple equation to estimate the effect) and the other chemical (removal of the dissolved phosphorus with ferric hydroxide).Support for this work came from CICYT (MAR88-0245 project) and Conselleria de Pesca de la Xunta de GaliciaPeer reviewe

Drug utilization study of antimicrobial agents in patients of neonatal sepsis in neonatal intensive care unit at a tertiary care hospital in western part of India

Background: Neonatal sepsis is one of the major causes of death and morbidity among neonates in India; however, studies related to neonatal sepsis are somewhat in limited numbers. Furthermore, time to time sensitivity and efficacy of various antimicrobial agents (AMA) change which necessitates studies related to antimicrobial drug utilization in hospitals. The objective of present study was to evaluate the pattern of use of AMAs in neonatal sepsis at the neonatal intensive care unit (NICU) at a tertiary care hospital in western part of India.Methods: It was a prospective cross-sectional study conducted over a period of 6-month duration in NICU at tertiary care hospital. Data were collected and analyzed.Results: It has been observed that 57.67% patients were pre-term, 42.32% full term; 23.28% were of normal birth weight, 58.73% low birth weight and 15.34% were very low birth weight. In 48.7% of patients, two different antibiotics were prescribed while in 40.1% of patients three different antibiotics were prescribed. A total number of antibiotics prescribed were 499, per patient 2.78 antibiotics were prescribed. Amikacin was used in 73.01% cases while cefotaxime was used in 64.55% of cases. Piperacilin + tazobactam combination was used in 41.26% cases. In 50.9% cases, antibiotics were prescribed by generic name.Conclusion: Antibiotic resistance is increasing due to the irrational prescribing habits of physicians, leading to increasing morbidity, mortality and treatment costs. Therefore, the medical professionals as well as government personnel who are related to the health sector need to understand that antibiotics are precious and finite resources. The remedy of this situation requires that regular educational awareness programs should be conducted in hospitals at a regular basis