955 research outputs found
Modelling of reversible single chain polymer self-assembly: from the polymer towards the protein limit
Data Center Security: Analysis of Two Audit Reports
The increasing volume of electronic data, the need for secure storage of this data and the necessity for organizations to prepare for disaster are key reasons promoting the prominence of data centers in our society. Since data centers house large volumes of valuable information, proper security of organizational data centers is essential. This paper provides the reader with an overview of security principles relevant to data centers. We then offer a synopsis, aggregation and exploratory analysis of two audit reports of government data centers in the United States. We suggest general observations from the audit reports before concluding. As a contribution to the literature, this paper offers an investigative analysis of data center audits that can form a baseline for a more thorough future study on this relevant topic
Hablas vielleicht un peu la mia language? A comprehensive overview of the role of language differences in headquarters-subsidiary communication
The management of human resources in headquarters (HQ)-subsidiary relationships requires intensive communication, but effective communication often depends on having a shared language. Hence, language differences can be a serious threat to the successful management of human resources in multinational corporations (MNCs). In this large-scale quantitative study, encompassing data from more than 800 subsidiaries in thirteen countries, we investigated four related issues.
First, in terms of the importance of language differences, we found that HQ-subsidiary relationships are clearly affected by language differences and that the latter form a distance category of their own, which should not be subsumed under the related, but separate concept of cultural differences. Second, regarding the consequences of language differences for communication outcomes, we found that a lack of a shared language is associated with misunderstanding, conflict and parallel information networks which could harm HQ-subsidiary interactions.
Third, with regard to the impact of language differences on communication methods, we found that alack of a shared language is associated witha significantly lower level of oral (face-to-face and phone) communication, but not written communication. Fourth, and finally, in terms of a potential solution to communication problems caused by language differences, we found that expatriates can facilitate both communication and knowledge transfer between HQ and subsidiaries
Photo-induced chemistry for the design of oligonucleotide conjugates and surfaces
A photocaged diene is introduced at the 5âČ-end of oligonucleotides using the H-phosphonate approach. The photoenol-functionalized DNA is subsequently employed for the conjugation to a protein and the spatially controlled immobilization onto surfaces using a light-induced DielsâAlder cycloaddition. Fully functional proteinâDNA conjugates and patterned DNA surfaces are obtained under mild irradiation conditions
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Electrically heated ex-reactor pellet-cladding interaction (PCI) simulations utilizing irradiated Zircaloy cladding. [PWR]
In a program sponsored by the Fuel Systems Research Branch of the US Nuclear Regulatory Commission, a series of six electrically heated fuel rod simulation tests were conducted at Pacific Northwest Laboratory. The primary objective of these tests was to determine the susceptibility of irradiated pressurized-water reactor (PWR) Zircaloy-4 cladding to failures caused by pellet-cladding mechanical interaction (PCMI). A secondary objective was to acquire kinetic data (e.g., ridge growth or relaxation rates) that might be helpful in the interpretation of in-reactor performance results and/or the modeling of PCMI. No cladding failures attributable to PCMI occurred during the six tests. This report describes the testing methods, testing apparatus, fuel rod diametral strain-measuring device, and test matrix. Test results are presented and discussed
Heterobimetallic Eu(III)/Pt(II) single-chain nanoparticles: a path to enlighten catalytic reactions
We introduce the formation and characterization of heterometallic single-chain nanoparticles entailing both catalytic and luminescent properties. A terpolymer containing two divergent ligand moieties, phosphines and phosphine oxides, is synthesized and intramolecularly folded into nanoparticles via a selective metal complexation of Pt(II) and Eu(III). The formation of heterometallic Eu(III)/Pt(II) nanoparticles is evidenced by size exclusion chromatography, multinuclear NMR (H, P{H}, F, Pt) as well as diffusion-ordered NMR and IR spectroscopy. Critically, we demonstrate the activity of the SCNPs as a homogeneous and luminescent catalytic system in the amination reaction of allyl alcohol
Flexible InkâJet Printed Polymer LightâEmitting Diodes using a SelfâHosted NonâConjugated TADF Polymer
Thermally activated delayed fluorescent (TADF) emitters have become the leading emissive materials for highly efficient organic light-emitting diodes (OLEDs). The deposition of these materials in scalable and cost-effective ways is paramount when looking toward the future of OLED applications. Herein, a simple OLED with fully solution-processed organic layers is introduced, where the TADF emissive layer is ink-jet printed. The TADF polymer has electron and hole conductive side chains, simplifying the fabrication process by removing the need for additional host materials. The OLED has a peak emission of 502 nm and a maximum luminance of close to 9600 cd m. The self-hosted TADF polymer is also demonstrated in a flexible OLED, reaching a maximum luminance of over 2000 cd m. These results demonstrate the potential applications of this self-hosted TADF polymer in flexible ink-jet printed OLEDs and, therefore, for a more scalable fabrication process
Hetero-DielsâAlder Cycloaddition with RAFT Polymers as Bioconjugation Platform
We introduce the bioconjugation of polymers synthesized by RAFT polymerization, bearing no specific functional end group, by means of heteroâDielsâAlder cycloaddition through their inherent terminal thiocarbonylthio moiety with a dieneâmodified model protein. Quantitative conjugation occurs over the course of a few hours, at ambient temperature and neutral pH, and in the absence of any catalyst. Our technology platform affords thermoresponsive bioconjugates, whose aggregation is solely controlled by the polymer chains
Hetero-Diels-Alder-Cycloaddition mit RAFT-Polymeren als Biokonjugationsplattform
Wir stellen die Biokonjugation von Polymeren vor, die durch RAFTâPolymerisation mittels HeteroâDielsâAlderâCycloaddition durch ihren inhĂ€renten terminalen Thiocarbonylthiorest mit einem dienmodifizierten Modellprotein synthetisiert wurden und keine spezifische funktionelle Endgruppe tragen. Die quantitative Konjugation erfolgt im Verlauf einiger Stunden bei Raumtemperatur und nahezu neutralem pHâWert und in Abwesenheit jeglichen Katalysators. Unsere Technologieplattform liefert thermoresponsive Biokonjugate, deren Aggregation allein durch die Polymerketten gesteuert wird
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