Gravity duals of 2d supersymmetric gauge theories

We find new supergravity solutions generated by D5-branes wrapping a four-cycle and preserving four and two supersymmetries. We first consider the configuration in which the fivebranes wrap a four-cycle in a Calabi-Yau threefold, which preserves four supersymmetries and is a gravity dual to the Coulomb branch of two-dimensional gauge theories with N=(2,2) supersymmetry. We also study the case of fivebranes wrapping a co-associative four-cycle in a manifold of G_2-holonomy, which provides a gravity dual of N=(1,1) supersymmetric Yang-Mills theory in two dimensions. We also discuss the addition of unquenched fundamental matter fields to these backgrounds and find the corresponding gravity solutions with flavor brane sources.Comment: 34 pages + appendices; v2: minor improvement

Quantum Critical Superfluid Flows and Anisotropic Domain Walls

We construct charged anisotropic AdS domain walls as solutions of a consistent truncation of type IIB string theory. These are a one-parameter family of solutions that flow to an AdS fixed point in the IR, exhibiting emergent conformal invariance and quantum criticality. They represent the zero-temperature limit of the holographic superfluids at finite superfluid velocity constructed in arXiv:1010.5777. We show that these domain walls exist only for velocities less than a critical value, agreeing in detail with a conjecture made there. We also comment about the IR limits of flows with velocities higher than this critical value, and point out an intriguing similarity between the phase diagrams of holographic superfluid flows and those of ordinary superconductors with imbalanced chemical potential.Comment: 11 pages, 3 figures. V2: Very minor corrections. JHEP versio

Holographic flavor on the Higgs branch

In this paper we study the holographic dual, in several spacetime dimensions, of the Higgs branch of gauge theories with fundamental matter. These theories contain defects of various codimensionalities, where the matter fields are located. In the holographic description the matter is added by considering flavor brane probes in the supergravity backgrounds generated by color branes, while the Higgs branch is obtained when the color and flavor branes recombine with each other. We show that, generically, the holographic dual of the Higgs phase is realized by means of the addition of extra flux on the flavor branes and by choosing their appropriate embedding in the background geometry. This suggests a dielectric interpretation in terms of the color branes, whose vacuum solutions precisely match the F- and D-flatness conditions obtained on the field theory side. We further compute the meson mass spectra in several cases and show that when the defect added has codimension greater than zero it becomes continuous and gapless.Comment: 59 pages, 1 figure;v2: references adde

Adding flavor to the gravity dual of non-commutative gauge theories

We study the addition of flavor degrees of freedom to the supergravity dual of the non-commutative deformation of the maximally supersymmetric gauge theories. By considering D7 flavor branes in the probe approximation and studying their fluctuations we extract the spectrum of scalar and vector mesons as a function of the non-commutativity. We find that the spectrum for very large non-commutative parameter is equal to the one in the commutative theory, while for some intermediate values of the non-commutativity some of the modes disappear from the discrete spectrum. We also study the semiclassical dynamics of rotating open strings attached to the D7-brane, which correspond to mesons with large spin. Under the effect of the non-commutativity the open strings get tilted. However, at small(large) distances they display the same Regge-like (Coulombic) behaviour as in the commutative theory. We also consider the addition of D5-flavor branes to the non-commutative deformation of the N=1 supersymmetric Maldacena-Nunez background.Comment: 50 pages, 9 figures, LaTeX; v2: minor improvements, references added; v3: typos correcte

Open string modes at brane intersections

We study systematically the open string modes of a general class of BPS intersections of branes. We work in the approximation in which one of the branes is considered as a probe embedded in the near-horizon geometry generated by the other type of branes. We mostly concentrate on the D3-D5 and D3-D3 intersections, which are dual to defect theories with a massive hypermultiplet confined to the defect. In these cases we are able to obtain analytical expressions for the fluctuation modes of the probe and to compute the corresponding mass spectra of the dual operators in closed form. Other BPS intersections are also studied and their fluctuation modes and spectra are found numerically.Comment: 58 pages, 3 figures, LaTeX;v2: typos correcte

Type IIB Holographic Superfluid Flows

We construct fully backreacted holographic superfluid flow solutions in a five-dimensional theory that arises as a consistent truncation of low energy type IIB string theory. We construct a black hole with scalar and vector hair in this theory, and study the phase diagram. As expected, the superfluid phase ceases to exist for high enough superfluid velocity, but we show that the phase transition between normal and superfluid phases is always second order. We also analyze the zero temperature limit of these solutions. Interestingly, we find evidence that the emergent IR conformal symmetry of the zero-temperature domain wall is broken at high enough velocity.Comment: v3: Published version. Figures 5 and 6 corrected. 24 pages, 7 figure

On D3-brane Potentials in Compactifications with Fluxes and Wrapped D-branes

We study the potential governing D3-brane motion in a warped throat region of a string compactification with internal fluxes and wrapped D-branes. If the Kahler moduli of the compact space are stabilized by nonperturbative effects, a D3-brane experiences a force due to its interaction with D-branes wrapping certain four-cycles. We compute this interaction, as a correction to the warped four-cycle volume, using explicit throat backgrounds in supergravity. This amounts to a closed-string channel computation of the loop corrections to the nonperturbative superpotential that stabilizes the volume. We demonstrate for warped conical spaces that the superpotential correction is given by the embedding equation specifying the wrapped four-cycle, in agreement with the general form proposed by Ganor. Our approach automatically provides a solution to the problem of defining a holomorphic gauge coupling on wrapped D7-branes in a background with D3-branes. Finally, our results have applications to cosmological inflation models in which the inflaton is modeled by a D3-brane moving in a warped throat.Comment: 45 pages, 1 figure; v2: added reference, clarified notatio

Holographic duals of SQCD models in low dimensions

We obtain gravity duals to supersymmetric gauge theories in two and three spacetime dimensions with unquenched flavor. The supergravity solutions are generated by a set of color branes wrapping a compact cycle in a Calabi-Yau threefold, together with another set of flavor branes extended along the directions orthogonal to the cycle wrapped by the color branes. We construct supergravity backgrounds which include the backreaction induced by a smeared set of flavor branes, which act as delocalized dynamical sources of the different supergravity fields.Comment: 42 pages, 5 figures;v2: typos correcte

Does publication bias inflate the apparent efficacy of psychological treatment for major depressive disorder? A systematic review and meta-analysis of US national institutes of health-funded trials

Background The efficacy of antidepressant medication has been shown empirically to be overestimated due to publication bias, but this has only been inferred statistically with regard to psychological treatment for depression. We assessed directly the extent of study publication bias in trials examining the efficacy of psychological treatment for depression. Methods and Findings We identified US National Institutes of Health grants awarded to fund randomized clinical trials comparing psychological treatment to control conditions or other treatments in patients diagnosed with major depressive disorder for the period 1972–2008, and we determined whether those grants led to publications. For studies that were not published, data were requested from investigators and included in the meta-analyses. Thirteen (23.6%) of the 55 funded grants that began trials did not result in publications, and two others never started. Among comparisons to control conditions, adding unpublished studies (Hedges’ g = 0.20; CI95% -0.11~0.51; k = 6) to published studies (g = 0.52; 0.37~0.68; k = 20) reduced the psychotherapy effect size point estimate (g = 0.39; 0.08~0.70) by 25%. Moreover, these findings may overestimate the "true" effect of psychological treatment for depression as outcome reporting bias could not be examined quantitatively. Conclusion The efficacy of psychological interventions for depression has been overestimated in the published literature, just as it has been for pharmacotherapy. Both are efficacious but not to the extent that the published literature would suggest. Funding agencies and journals should archive both original protocols and raw data from treatment trials to allow the detection and correction of outcome reporting bias. Clinicians, guidelines developers, and decision makers should be aware that the published literature overestimates the effects of the predominant treatments for depression