Uso de internet para evaluar el distrés psicológico en pacientes con cáncer de mama

Objective: The object of this study is to determine the prevalence of distress symptoms and coping strategy among a large sample of Spanish-speaking breast cancer patients recruited on-line. Methods: We designed a cross-sectional study with breast cancer survivors (n=434) that were accrued via Internet (http://www.cancermama.org). Participants completed a demographic and medical questionnaire, and they were also evaluated using self-reporting measures of psychological distress and adjustment to cancer; the 14-item Hospital Anxiety and Depression Scale (HADS) and the 29-item version of the Mental Adjustment to Cancer Scale (Mini-MAC), respectively. Results: Global HAD as a measure of distress on-line is reliable in our study. The overall prevalence rate of distress for our sample was 50%, with no differences for socio-demographics or medical status variables. Concerning to anxiety punctuation 66.2% were clinical cases and 34.5% reached the clinical level for depression. These results were associated with Mini-MAC scales as expected. Conclusions: These results offer support for the use of Internet as valid tool for the psychological distress assessment in patients with breast cancer Spanish-speaking patients. Internet brings us the possibility to identify high-risk patients through psychological screening in order to provide early interventions, and Global HAD punctuation may be an accurate tool. However more studies are needed to analyze internet illness consulting situation as an anxious provoking space.Objetivo: El objetivo de este estudio es determinar la prevalencia de síntomas de distrés y la estrategia de adaptación entre una amplia muestra de pacientes de habla hispana con cáncer de mama mediante el uso de internet.Métodos: Se diseñó un estudio transversal con pacientes con cáncer de mama (n = 434) reclutadas a través de Internet (http://www.cancermama.org). Las participantes completaron un cuestionario demográfico y médico, y también se usaron cuestionarios de evaluación psicológica ampliamente utilizados en Psicooncología, la HADs (Escala de Ansiedad y Depresión Hospitalaria) y la escala MAC (La Escala de Ajuste Mental al Cáncer), en su versión reducida de 29 ítems (Mini-MAC). Resultados: En nuestro estudio el resultado global de la HADs como medida de distrés en línea es confiable en nuestro estudio. La tasa de prevalencia general de distrés para nuestra muestra fue del 50%, sin diferencias según nivel socio-demográfico o variables médicas. En cuanto a puntuación de ansiedad 66,2% y 34% alcanzaron nivel clínico de ansiedad y depresión, respectivamente. Estos resultados se relacionaron con los de la Mini-MAC según lo esperado. Conclusiones: Estos resultados dan apoyo al uso de Internet como herramienta válida para la evaluación de los trastornos psicológicos en pacientes con cáncer de mama. Internet nos brinda la posibilidad de identificar pacientes de alto riesgo a través de screening psicológico con el fin de realizar intervenciones tempranas, y las puntuaciones globales de distrés pueden ser una herramienta precisa. Sin embargo se necesitan más estudios para analizar la situación de consulta en internet como un estímulo provocador de ansiedad

Obesity dependent metabolic signatures associated with nonalcoholic fatty liver disease progression

Our understanding of the mechanisms by which nonalcoholic fatty liver disease (NAFLD) progresses from simple steatosis to steatohepatitis (NASH) is still very limited. Despite the growing number of studies linking the disease with altered serum metabolite levels, an obstacle to the development of metabolome-based NAFLD predictors has been the lack of large cohort data from biopsy-proven patients matched for key metabolic features such as obesity. We studied 467 biopsied individuals with normal liver histology (n=90) or diagnosed with NAFLD (steatosis, n=246; NASH, n=131), randomly divided into estimation (80% of all patients) and validation (20% of all patients) groups. Qualitative determinations of 540 serum metabolite variables were performed using ultra-performance liquid chromatography coupled to mass spectrometry (UPLCMS). The metabolic profile was dependent on patient body-mass index (BMI), suggesting that the NAFLD pathogenesis mechanism may be quite different depending on an individual’s level of obesity. A BMI-stratified multivariate model based on the NAFLD serum metabolic profile was used to separate patients with and without NASH. The area under the receiver operating characteristic curve was 0.87 in the estimation and 0.85 in the validation group. The cutoff (0.54) corresponding to maximum average diagnostic accuracy (0.82) predicted NASH with a sensitivity of 0.71 and a specificity of 0.92 (negative/positive predictive values = 0.82/0.84). The present data, indicating that a BMI-dependent serum metabolic profile may be able to reliably distinguish NASH from steatosis patients, have significant implications for the development of NASH biomarkers and potential novel targets for therapeutic intervention

Pre-service teachers' critical digital literacy skills and attitudes to address social problems

The emergence and expansion of social networks in the digital age has led to social transformations that have a great impact within the field of education. Teacher-training programs face the challenge of preparing future teachers to critically interpret digital media. They must succeed in this if we are to develop citizens who are well informed and reflective, which then raises the question: Are future teachers critical thinkers? This study took third- and fourth-year students of primary education (n = 322) at five Spanish universities and explored their capacity for constructing critical discourses. It examined how well they can analyze and discuss information from digital media on social problems like poverty, economic crises, social justice, and the media. Its findings reveal that future teachers have difficulty in putting together critical discourses based on information from the Internet on social problems. Those who have doubts, compare, analyze, and reason are the minority

New Media and Support for Same-Sex Marriage

Research in advanced industrialized democracies on social attitudes toward same-sex marriage suggests that intergroup social contact and positive media coverage play an important role in promoting tolerance and support for same-sex marriage. Using AmericasBarometer survey data for eighteen countries in 2010, 2012, and 2014, this article examines the ways in which individual-level Internet use interacts with news exposure, country-level quality of democracy, Internet penetration, and their association with support for same-sex marriage. The results suggest that not only is Internet use associated with greater support for same-sex marriage, but that among those who both use the Internet and pay more attention to the news, the positive effects are amplified. In addition, national level of democracy, economic development, and Internet use are also associated with overall higher probabilities of supporting same-sex marriage. We find that Internet use has a strong positive association with the probability of supporting same-sex marriage as the percentage of the national population on the Internet increases. These findings extend our understanding of social and political tolerance of same-sex marriage in Latin America. Investigación en países industrializados sugiere que el contacto entre grupos sociales y la cobertura positiva de los mismos en medios de comunicación juegan un papel importante en la promoción de tolerancia y en aumentar apoyo al matrimonio entre personas del mismo sexo. Basándonos en las encuestas del AmericasBarometer de 2010, 2012 y 2014, este artículo examina cómo el uso de la Internet interactúa con el consumo de noticias, la calidad de la democracia en el país, el grado nacional de penetración de la Internet, y su asociación con mayor apoyo al matrimonio igualitario. Estos resultados sugieren que no solamente existe una asociación entre el uso de la Internet y apoyo al matrimonio igualitario, pero que esta asociación amplifica los efectos positivos entre las personas que usan la Internet y prestan atención a las noticias. Además, la calidad de la democracia al nivel nacional, niveles de desarrollo económico, así como el uso de la Internet están también asociados con probabilidades mayores de apoyo. Encontramos que existe una fuerte asociación positiva entre el uso de la Internet y probabilidades de mayor apoyo conforme aumenta el porcentaje de la población con acceso a la Internet

Design of the Front End Electronics for the Infrared Camera of JEM-EUSO, and manufacturing and verification of the prototype model

The Japanese Experiment Module (JEM) Extreme Universe Space Observatory (EUSO) will be launched and attached to the Japanese module of the International Space Station (ISS). Its aim is to observe UV photon tracks produced by ultra-high energy cosmic rays developing in the atmosphere and producing extensive air showers. The key element of the instrument is a very wide-field, very fast, large-lense telescope that can detect extreme energy particles with energy above $10^{19}$ eV. The Atmospheric Monitoring System (AMS), comprising, among others, the Infrared Camera (IRCAM), which is the Spanish contribution, plays a fundamental role in the understanding of the atmospheric conditions in the Field of View (FoV) of the telescope. It is used to detect the temperature of clouds and to obtain the cloud coverage and cloud top altitude during the observation period of the JEM-EUSO main instrument. SENER is responsible for the preliminary design of the Front End Electronics (FEE) of the Infrared Camera, based on an uncooled microbolometer, and the manufacturing and verification of the prototype model. This paper describes the flight design drivers and key factors to achieve the target features, namely, detector biasing with electrical noise better than $100 \mu$V from $1$ Hz to $10$ MHz, temperature control of the microbolometer, from $10^{\circ}$C to $40^{\circ}$C with stability better than $10$ mK over $4.8$ hours, low noise high bandwidth amplifier adaptation of the microbolometer output to differential input before analog to digital conversion, housekeeping generation, microbolometer control, and image accumulation for noise reduction

Subzero Temperature Storage to Preserve the Quality Attributes of Veiled Virgin Olive Oil

Unfiltered olive oils (UO) have gained popularity in the global market, but they lose their quality characteristics faster than filtered oils (FO). In this work, refrigeration and freezing temperatures were explored to maintain UO quality features during storage. A full factorial design was applied to an UO and to the same oil after filtration to evaluate the effect of storage temperature (room temperature, 4 ◦C and –20 ◦C) and freezing speed (slow-freezing, in the freezer at −20 ◦C and fast-freezing, in a bath of liquid nitrogen). Official quality parameters, polar and nonpolar phenolic compounds, oxidative stability index, volatile compounds and descriptive sensory profile were measured periodically over 24 months of storage in the dark. Storage temperature influenced the quality of both UO and FO, but in different ways. At non-freezing temperature, UO experienced a severe decrease in its sensory quality compared to FO, mainly due to the hydrolysis of secoiridoids and degradation of the volatile fraction, but storage at −20 ◦C allowed to effectively preserve UO quality traits, thus resulting as a suitable strategy to increase the shelf-life of UO to satisfy the demand of consumers for this particular product. The results showed that slow-freezing was the most appropriate method for freezing.info:eu-repo/semantics/publishedVersio

Effect of the Storage Conditions and Freezing Speed on the Color and Chlorophyll Profile of Premium Extra Virgin Olive Oils

Premium extra virgin olive oils (PEVOO) are oils of exceptional quality and retail at high prices. The green color of recently extracted olive oils is lost during storage at room temperature, mainly because of the pheophytinization of chlorophylls. Since a green color is perceived as a mark of high-quality oils by consumers, it is especially important for PEVOO to maintain their initial green color. This study assessed the effect of applying low temperatures (refrigeration and freezing) and modified atmospheres on the color of four PEVOO for 24 months. Also, the effect of two freezing methods (slow freezing by placing the oil at −20 ◦C and fast freezing by immersing the oil in a bath of liquid nitrogen) was studied. Results showed that the green color was better preserved in oils frozen and stored at −20 ◦C whereas in oils frozen with liquid nitrogen the green color was lost much faster during frozen storage. An in-depth study of this unexpected phenomenon showed that this loss of green color was mainly due to a pheophytinization of chlorophylls. This phenomenon did not happen at the moment of freezing with liquid nitrogen, but over the first 100 days of storage at −20 ◦C. In addition, correlations between single chlorophyll and pheophytin contents and chromatic coordinates were established.info:eu-repo/semantics/publishedVersio