343 research outputs found
PENGEMBANGAN PROGRAM INTERVENSI DINI BERSUMBERDAYA KELUARGA PADA ANAK CEREBRAL PALSY DENGAN HAMBATAN KOMUNIKASI
Penelitian ini dilatarbelakangi oleh kurangnya pemahaman, penerimaan, dan sikap orang tua terhadap hambatan yang dihadapi anak. Hal ini berdampak pada kemampuan keluarga dalam memberikan layanan intervensi dini di rumah. Tujuan dari penelitian ini adalah untuk merumuskan program intervensi dini bersumber daya keluarga yang akan menjadi pedoman orang tua dalam melaksanakan intervensi. Penelitian ini menggunakan pendekatan kualitatif dengan metode deskriptif. Subjek dalam penelitian ini adalah satu keluarga yang memiliki anak Cerebral Palsy dengan hambatan komunikasi di Ciamis. Teknik pengumpulan data yang digunakan adalah observasi, wawancara, dan studi dokumentasi. Hasil penelitian menunjukkan bahwa: 1) anak memiliki hambatan komunikasi yang pencapaian perkembangan komunikasi verbalnya setara dengan anak usia 2-3 tahun dan usia kalender saat ini 5 tahun. 2) rendahnya tingkat pemahaman orangtua terhadap hambatan anak. 3). Rumusan program intervensi dini bersumber daya keluarga ini berdasarkan kondisi objektif serta kebutuhan keluarga dan anak. 4). tingkat pemahaman orang tua mengenai hambatan anak meningkat serta terjadi perubahan sikap dan perilaku orang tua kepada anak;--- The study was motivated by the lack of understanding, acceptance as well as the attitude of the parents toward their child’s obstacles. It somehow has an impact on family’s capacity to give early intervention support at home. This study was aimed at formulating an early intervention program to the child. The study used descriptive qualitative method involving a single family having a child suffering from Cerebral Palsy causing communication barrier at Ciamis. The techniques used in collecting the data were observations, interviews, and document analysis. The study revealed several findings as follows: 1) the child had communication barrier which made her communication verbal developmental stage was equal to 2-3 years old children. 2) The lack of understanding, acceptance and attitude of the parents toward their child’s communication barrier as well as the support in delivering early intervention at home. 3) The early intervention family-based program’s formulation was based on the objective condition as well as the needs’ of both the child and the parents. 4) The level understanding parents of the barriers to child increase and a change in attitudes and behavior of parents to child
Palladium-Catalyzed Allylic Substitution at Four-Membered-Ring Systems: Formation of η<sup>1</sup>-Allyl Complexes and Electrocyclic Ring Opening
Caught in the act: A series of unique η1-allyl palladium complexes of four-membered cyclic systems bearing β-hydrogens were prepared (see structure). Their unusual structure, reactivity, and unprecedented propensity for undergoing pericyclic reactions were uncovered
Antibody-Drug Conjugates in Urothelial Carcinoma: A New Therapeutic Opportunity Moves from Bench to Bedside
Direct Domino Synthesis of Azido-Dienoic Acids: Potential Linker Units
We report an atom-economical domino synthesis of functionalized and stereodefined dienes. This method hinges on an allylic alkylation–electrocyclic ring-opening sequence and allows direct access to doubly vinylogous azido-dienoic acids bearing challenging substitution patterns. This class of compounds represents useful linkers in chemical biology by virtue of the orthogonality between the azido and carboxylic acid moieties
Taxonomy of the ant genus Nesomyrmex Wheeler (Formicidae, Myrmicinae) in the Afrotropical region, with a review of current species groups and description of a new species of the N-angulatus group from Mozambique
This study reviews the taxonomy of the ant genus Nesomyrmex Wheeler, 1910 in the
Afrotropical region. Previous revisionary studies are discussed and four species groups are proposed on the basis of external morphology. The N. angulatus group contains seven species that are widely distributed throughout the whole Afrotropical region, with one species also occurring in the Palaearctic and Malagasy regions. The N. cataulacoides group is monotypic, with one morphologically bizarre species found in Equatorial rain forests. The N. humerosus group is also monotypic and occurs in East Africa. The last and by far most species-rich group is the N. simoni group that contains 17 species, all of which are endemic to South Africa. The four groups are defined for the first time for the region, and an illustrated identification key is provided. Furthermore, the N. angulatus group is more thoroughly reviewed. One new species from Mozambique is described, N. inhaca sp. nov., and species accounts for the other six are provided. Also, an illustrated identification key to the species of the N. angulatus group is presented.journal articl
Macro-moth (Lepidoptera) Diversity of a Newly Shaped Ecological Corridor and the Surrounding Forest Area in the Western Italian Alps
Evaluación de la reparación de defectos óseos corticales tratados con matriz ósea desmineralizada con oxitetraciclina.
La oxitetraciclina es un antibiótico con afinidad de depósito en los sitios de hueso nuevo. Por ese motivo es empleada para realizar estudios histomorfométricos. El objetivo del presente trabajo fue determinar la evolución de la reparación de defectos diafisiarios circulares tratados con matriz ósea desmineralizada (MOD) mediante la fluorescencia emitida por la oxitetraciclina. El estudio se realizó en 11 conejos sexualmente maduros a los que se les practicó un defecto circular de 3 mm en una de las cortezas femorales. Los defectos de 9 animales que conformaron el grupo tratamiento fueron rellenados con MOD, los otros 2 conejos no recibieron tratamiento y constituyeron el grupo control. Los animales tratados se sacrificaron en grupos de 3, a las 2, 4 y 6 semanas. En el tiempo que duraron los tratamientos recibieron 70 mg de oxitetraciclina/kg/día vía oral. Las muestras obtenidas provenientes de los defectos se dividieron para ser teñidas con hematoxilina y eosina (HE) para identificar los cambios histológicos y el resto para observar la fluorescencia emitida con luz ultravioleta. Las capturas adquiridas se analizaron con el software ImageJ. A las 2 semanas las tinciones con HE mostraron que el defecto contenía osteoide con preosteoblastos y osteoblastos mientras que las mismas estructuras contenían pequeños sectores aislados fluorescentes. A las 4 semanas el sitio de reparación contenía trabéculas nuevas integradas a las cortezas, éstas mostraron mayor fluorescencia en los sitios de la matriz que rodeaban a los osteoblastos. Luego de 6 semanas el hueso nuevo fue más fluorescente respecto al hueso circundante. En los inicios de la reparación ósea cuando el osteoide comienza a mineralizarse se detecta fluorescencia como marcador de la actividad de la reparación ósea promovida por la MOD. La actividad ósea progresó en los controles, tanto en las trabéculas nuevas como en el hueso reparado a las 6 semanas posquirúrgica
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