30 research outputs found
Relazione sull'attivita' svolta dal 15 Marzo al 7 Marzo 2003
Consiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome / CNR - Consiglio Nazionale delle RichercheSIGLEITItal
Delineation of the larynx as organ at risk in radiotherapy: a contouring course within “Rete Oncologica Piemonte-Valle d’Aosta” network to reduce inter- and intraobserver variability
Aims: To evaluate the usefulness of a contouring course in reducing inter- and intraobserver variability in the definition of the larynx as organ at risk (OAR). Methods: Within the “Rete Oncologica Piemonte-Valle d’Aosta” network, a contouring course focusing on larynx delineation was proposed. Twenty-six radiotherapist technicians (RTTs) experienced in delineating OARs were asked to contour larynx before and after the training. An expert radiation oncologist defined the reference volume for educational purpose. The contoured volumes obtained before and after the course were compared using descriptive statistics (mean value, standard deviation—SD, and coefficient of variation—COV) of volumes and maximum diameters. Conformity index (CI), dice coefficient (DC), and percentage of overlap were used to evaluate the spatial accuracy of the different volumes compared to the reference. Further analysis regarding the variation in the centre of mass (COM) displacement was performed. Results: The mean volume was 40.4 cm3 before and 65.9 cm3 after the course, approaching the reference value. Mean anteroposterior, laterolateral, and craniocaudal diameters improved, getting each closer to the reference. Moreover, the COM moved approaching reference coordinates. Mean percentage of intersection and DC strongly increased after the course, rising from 57.76 to 93.83 % and from 0.68 to 0.89, respectively. CI enhanced from 0.06 to 0.31. Conclusions: This study shows an improvement in larynx definition after the contouring course with lower interobserver variability and major consistency compared to the reference volume. Other specific educational activities may further increase the quality of radiation therapy contouring in this setting
Relazione sull'attivita' svolta dal Difensore civico della Regione autonoma Valle d'Aosta dal 10 marzo 2003 al 12 marzo 2004
Consiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7 , Rome / CNR - Consiglio Nazionale delle RichercheSIGLEITItal
Second-line treatment of partially-platinum-sensitive recurrent ovarian cancer: a MANGO - PIEMONTE E VALLE D'AOSTA CANCER NETWORK Italian multicentric retrospective study.
Jaw osteonecrosis associated with intravenous bisphosphonate: is incidence reduced after adoption of dental preventive measures?
Non esiste Abstract in quanto è una lettera all'Editore pubblicata ed indicizzata
\u201cStudy Group Jaw osteonecrosis associated with intravenous bisphosphonate: is incidence reduced after adoption of dental preventive measures?\u201d
Groundwater-level risk assessment by using statistical and geographic information system (GIS) techniques: a case study in the Aosta Valley region, Italy
In the present study, groundwater-level monitoring has been carried out on 26 observation dug wells in the Aosta Valley region, Italy, during the dry season (June 2013) and wet season (November 2013) in order to assess the water-level fluctuation (WLF). The depth to water level varied from 3.04 to 28.70Â metres below ground level (mbgl) in the dry season and from 2.92 to 25.62 mbgl in the wet season. The WLF of the study area varied from 0.01 to 6.80 mbgl, and the western and north-western regions of the study area showed higher WFL. The WLF map was validated with a statistical analysis and elevation value of the area in a geographic information system environment, and this indicated that validation can be accepted for the WLF in the Aosta Valley. The results of the study demonstrated that the eastern region could be considered as a safe and good recharge zone for the groundwater in the Aosta Valley region. The WLF map generated in this study could also be used for the management of future groundwater resources and environmental planning of the area