17 research outputs found

    How Well Can We Infer the Properties of the Solar Acoustic Sources

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    Measurements of the p-mode line asymmetry in the solar oscillation velocity power spectrum have been used on several occasions to infer the properties of the acoustic sources. These inferences are based on the assumption that, unlike the observed intensity signal, the velocity signal does not contain a nonresonant (background) component that is correlated with the p-mode signal. Line asymmetry measurements have also been used to draw inferences on the nature of the correlated background signal that is present in intensity observations. By simultaneously modeling the observed velocity and intensity power spectra and the intensity-velocity cross spectrum, we enforce strict observational constraints on the properties of the fitting model. We find that in order to accurately describe the observed data, we have to include a correlated background component in both our models for the V and I signals at low frequencies. Our results also show that we cannot uniquely determine the acoustic source depth for low-frequency waves or the detailed properties of the correlated background signals. It appears that further physical and/or observational constraints are needed before we can obtain this information

    Data reduction pipeline for MOF-based synoptic telescopes

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    There are strong scientific cases and practical reasons for building ground-based solar synoptic telescopes. Some issues, like the study of solar dynamics and the forecasting of solar flares, benefit from the 3D reconstruction of the Sun’s atmosphere and magnetic field. Others, like the monitoring and prediction of space weather, require full disk observations, at the proper sampling rate, combining H-alpha images and Doppler velocity and magnetic field. The synoptic telescopes based on Magneto Optical Filters (MOF) using different lines are capable of measuring the line-of-sight Doppler velocity and magnetic field over the full solar disk at different ranges of height in the Sun’s photosphere and low chromosphere. Instruments like the MOTH (Magneto-Optical filters at Two Heights), using a dual-channel based on MOFs operating at 589.0 nm (Na D2 line) and 769.9 nm (K D1 line), the VAMOS instrument (Velocity And Magnetic Observations of the Sun), operating at 769.9 nm (K D1 line), and the future TSST (Tor Vergata Synoptic Solar Telescope), using a dual-channel telescope operating at 656.28 nm (H-alpha line) and at 769.9 nm (K D1 line), allow to face both aspects, the scientific and the operative related to Space Weather applications. The MOTH, VAMOS and TSST data enable a wide variety of studies of the Sun, from seismic probing of the solar interior (sound speed, rotation, details of the tachocline, sub-surface structure of active regions), to the dynamics and magnetic evolution of the lower part of the solar atmosphere (heating of the solar atmosphere, identification of the signatures of solar eruptive events, atmospheric gravity waves, etc.), to the 3D reconstruction of the solar atmosphere and flare locations. However, the use of MOF filters requires special care in calibrating the data for scientific or operational use. This work presents a systematic pipeline that derives from the decennial use of MOF’s technology. More in detail, the pipeline is based on data reduction procedures tested and validated on MOTH data acquired at Mees Solar Observatory of the University of Hawaii Haleakala Observatories and at South Pole Solar Observatory (SPSO), at the Amundsen-Scott South Pole Station in Antarctica, during Antarctica Summer Campaign 2016/17

    Textiles sismographes : Symposium fibres et textiles 1995, actes du colloque = Textiles sismographes : Texts from the Colloquium

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    A collection of texts presented at a colloquium on fibres and textiles by 11 artists, 12 critics and teachers, and students. The authors puzzle over the notion of a "textile identity" and the problem of successfully integrating theory and practice in textile work. Essays are printed in original language with corresponding brief French or English abstracts. Biographical notes. 39 bibl. ref

    Complete genome sequence of Beutenbergia cavernae type strain (HKI 0122).

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    Beutenbergia cavernae (Groth et al. 1999) is the type species of the genus and is of phylogenetic interest because of its isolated location in the actinobacterial suborder Micrococcineae. B. cavernae HKI 0122(T) is a Gram-positive, non-motile, non-spore-forming bacterium isolated from a cave in Guangxi (China). B. cavernae grows best under aerobic conditions and shows a rod-coccus growth cycle. Its cell wall peptidoglycan contains the diagnostic L-lysine ← L-glutamate interpeptide bridge. Here we describe the features of this organism, together with the complete genome sequence, and annotation. This is the first completed genome sequence from the poorly populated micrococcineal family Beutenbergiaceae, and this 4,669,183 bp long single replicon genome with its 4225 protein-coding and 53 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project

    Neuropathy target esterase impairments cause Oliver–McFarlane and Laurence–Moon syndromes

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    BackgroundOliver-McFarlane syndrome is characterised by trichomegaly, congenital hypopituitarism and retinal degeneration with choroidal atrophy. Laurence-Moon syndrome presents similarly, though with progressive spinocerebellar ataxia and spastic paraplegia and without trichomegaly. Both recessively inherited disorders have no known genetic cause.MethodsWhole-exome sequencing was performed to identify the genetic causes of these disorders. Mutations were functionally validated in zebrafish pnpla6 morphants. Embryonic expression was evaluated via in situ hybridisation in human embryonic sections. Human neurohistopathology was performed to characterise cerebellar degeneration. Enzymatic activities were measured in patient-derived fibroblast cell lines.ResultsEight mutations in six families with Oliver-McFarlane or Laurence-Moon syndrome were identified in the PNPLA6 gene, which encodes neuropathy target esterase (NTE). PNPLA6 expression was found in the developing human eye, pituitary and brain. In zebrafish, the pnpla6 curly-tailed morphant phenotype was fully rescued by wild-type human PNPLA6 mRNA and not by mutation-harbouring mRNAs. NTE enzymatic activity was significantly reduced in fibroblast cells derived from individuals with Oliver-McFarlane syndrome. Intriguingly, adult brain histology from a patient with highly overlapping features of Oliver-McFarlane and Laurence-Moon syndromes revealed extensive cerebellar degeneration and atrophy.ConclusionsPreviously, PNPLA6 mutations have been associated with spastic paraplegia type 39, Gordon-Holmes syndrome and Boucher-Neuhäuser syndromes. Discovery of these additional PNPLA6-opathies further elucidates a spectrum of neurodevelopmental and neurodegenerative disorders associated with NTE impairment and suggests a unifying mechanism with diagnostic and prognostic importance
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