Gifted Education: Looking at Alternatives for Small, Rural Secondary Schools

Is enrichment or acceleration more suitable for gifted youth in rural areas

The Impact of a Two-Visit Occupational Therapy Home Modification Model on Low-Income Older Adults

Background: Various studies support the benefit of occupational therapist-led home modification to support successful aging in place for older adults. However, methodological differences limit generalizability. This study aimed to determine the impact of a replicable two-visit occupational therapy home modification program on occupational performance of low-income, community-dwelling older adults. Method: The researcher used a quasi-experimental one group pretest-posttest design. The participants were low-income homeowners, age 55 years and older, with decreased performance and/or satisfaction in one or more ADLs and IADLs as determined by the COPM. An occupational therapist provided the participants with a home safety assessment using the Rebuilding Together Safe at Home Checklist, along with a follow-up visit to deliver equipment and education. Results: Data analysis using paired t-tests revealed statistically significant increases in COPM performance and satisfaction ratings from pretest to posttest for the nine participants. The mean average total costs for home modification were $10,396.65 compared to average annual health care costs from$22,763 to $154,478. Conclusion: A two-visit model of occupational therapist-led home modifications benefits low-income older adults. This study provides support for these cost-effective services in support of AOTA’s Vision 2025, to maximize health, well-being, and quality of life for all people, populations, and communities through effective solutions that facilitate participation in everyday living

Developmental Effects of Perfluorononanoic Acid in the Mouse Are Dependent on Peroxisome Proliferator-Activated Receptor-Alpha

Perfluorononanoic acid (PFNA) is one of the perfluoroalkyl acids found in the environment and in tissues of humans and wildlife. Prenatal exposure to PFNA negatively impacts survival and development of mice and activates the mouse and human peroxisome proliferator-activated receptor-alpha (PPARα). In the current study, we used PPARα knockout (KO) and 129S1/SvlmJ wild-type (WT) mice to investigate the role of PPARα in mediating PFNA-induced in vivo effects. Pregnant KO and WT mice were dosed orally with water (vehicle control: 10 ml/kg), 0.83, 1.1, 1.5, or 2 mg/kg PFNA on gestational days (GDs) 1–18 (day of sperm plug = GD 0). Maternal weight gain, implantation, litter size, and pup weight at birth were unaffected in either strain. PFNA exposure reduced the number of live pups at birth and survival of offspring to weaning in the 1.1 and 2 mg/kg groups in WT. Eye opening was delayed (mean delay 2.1 days) and pup weight at weaning was reduced in WT pups at 2 mg/kg. These developmental endpoints were not affected in the KO. Relative liver weight was increased in a dose-dependent manner in dams and pups of the WT strain at all dose levels but only slightly increased in the highest dose group in the KO strain. In summary, PFNA altered liver weight of dams and pups, pup survival, body weight, and development in the WT, while only inducing a slight increase in relative liver weight of dams and pups at 2 mg/kg in KO mice. These results suggest that PPARα is an essential mediator of PFNA-induced developmental toxicity in the mouse

The Ursinus Weekly, October 12, 1972

Freshman voters elect leaders • Senator George L. Murphy to speak at convocation - dedication ceremonies • Continued false alarms may bring restrictions • Messiah\u27s annual performance slated for December 7th • Student-teachers assignments presented to seniors • Editorial: The Weekly wants you! • Student from Sri-Lanka speaks to Socratic Club • Stenzler sculpture in review: A good show • ProTheatre presents: Albee\u27s American dream • Faculty portrait: Emilio Paul • Bear Gridders win first • Harriers return to winning ways; Roll over three opponents • Aggressive play leads to victory at Goucher games • Manning takes helm; Aggression made keyhttps://digitalcommons.ursinus.edu/weekly/1087/thumbnail.jp

A review of fatty acid profiles and antioxidant content in grass-fed and grain-fed beef

Abstract Growing consumer interest in grass-fed beef products has raised a number of questions with regard to the perceived differences in nutritional quality between grass-fed and grain-fed cattle. Research spanning three decades suggests that grass-based diets can significantly improve the fatty acid (FA) composition and antioxidant content of beef, albeit with variable impacts on overall palatability. Grass-based diets have been shown to enhance total conjugated linoleic acid (CLA) (C18:2) isomers, trans vaccenic acid (TVA) (C18:1 t11), a precursor to CLA, and omega-3 (n-3) FAs on a g/g fat basis. While the overall concentration of total SFAs is not different between feeding regimens, grass-finished beef tends toward a higher proportion of cholesterol neutral stearic FA (C18:0), and less cholesterol-elevating SFAs such as myristic (C14:0) and palmitic (C16:0) FAs. Several studies suggest that grassbased diets elevate precursors for Vitamin A and E, as well as cancer fighting antioxidants such as glutathione (GT) and superoxide dismutase (SOD) activity as compared to grain-fed contemporaries. Fat conscious consumers will also prefer the overall lower fat content of a grass-fed beef product. However, consumers should be aware that the differences in FA content will also give grass-fed beef a distinct grass flavor and unique cooking qualities that should be considered when making the transition from grain-fed beef. In addition, the fat from grass-finished beef may have a yellowish appearance from the elevated carotenoid content (precursor to Vitamin A). It is also noted that grain-fed beef consumers may achieve similar intakes of both n-3 and CLA through the consumption of higher fat grain-fed portions

A national clinician–educator program: a model of an effective community of practice

Background: The increasing complexity of medical training often requires faculty members with educational expertise to address issues of curriculum design, instructional methods, assessment, program evaluation, faculty development, and educational scholarship, among others. Discussion: In 2007, The Royal College of Physicians & Surgeons of Canada responded to this need by establishing the first national clinician–educator program. We define a clinician–educator and describe the development of the program. Adopting a construct from the business community, we use a community of practice framework to describe the benefits (with examples) of this program and challenges in developing it. The benefits of the clinician–educator program include: improved educational problem solving, recognition of educational needs and development of new projects, enhanced personal educational expertise, maintenance of professional satisfaction and retention of group members, a positive influence within the Royal College, and a positive influence within other Canadian academic institutions. Summary: Our described experience of a social reorganization – a community of practice – suggests that the organizational and educational benefits of a national clinician–educator program are not theoretical, but real

Effects of perfluorooctanoic acid on mouse mammary gland development and differentiation resulting from cross-foster and restricted gestational exposures

The adverse consequences of developmental exposures to perfluorooctanoic acid (PFOA) are established in mice, and include impaired development of the mammary gland (MG). However, the relationships between timing or route of exposure, and consequences in the MG have not been characterized. To address the effects of these variables on the onset and persistence of MG effects in female offspring, timed pregnant CD-1 dams received PFOA by oral gavage over various gestational durations. Cross-fostering studies identified the 5 mg/kg dose, under either lactational- or intrauterine-only exposures, to delay MG development as early as postnatal day (PND) 1, persisting beyond PND 63. Intrauterine exposure during the final days of pregnancy caused adverse MG developmental effects similar to that of extended gestational exposures. These studies confirm a window of MG sensitivity in late fetal and early neonatal life, and demonstrate developmental PFOA exposure results in early and persistent MG effects, suggesting permanent consequences

In Vitro Cell Culture Infectivity Assay for Human Noroviruses

A 3-dimensional organoid human small intestinal epithelium model was used