18,292 research outputs found
ATP as a presynaptic modulator
© 2000 Elsevier Science Inc.There is considerable evidence that ATP acts as a fast transmitter or co-transmitter in autonomic and sensory nerves mostly through activation of ionotropic P2X receptors but also through metabotropic P2Y receptors. By analogy, the observations that ATP is released from stimulated central nervous
system (CNS) nerve terminals and that responses to exogenously added ATP can be recorded in central neurons, lead to the proposal that ATP might also be a fast transmitter in the CNS. However, in spite of
the robust expression of P2 receptor mRNA and binding to P2 receptors in the CNS, the demonstration of central purinergic transmission has mostly remained elusive. We now review evidence to suggest that ATP may also act presynaptically rather than solely postsynaptically in the nervous system.Fundação Ciência e Tecnologia and European nio
Deflationary cosmology: constraints from angular size and ages of globular clusters
Observational constraints to a large class of decaying vacuum cosmologies are
derived using the angular size data of compact radio sources and the latest age
estimates of globular clusters. For this class of deflationary
models, the present value of the vacuum energy density is quantified by a
positive parameter smaller than unity. In the case of milliarcsecond
compact radio-sources, we find that the allowed intervals for and the
matter density parameter are heavily dependent on the value of the
mean projected linear size . For pc, the best
fit occurs for , , and , , respectively. This analysis shows that if
one minimizes for the free parameters , and
, the best fit for these angular size data corresponds to a decaying
with and
pc. Constraints from age estimates of globular clusters and old high redshift
galaxies are not so restrictive, thereby suggesting that there is no age crisis
for this kind of cosmologies.Comment: 6 pages, 3 figures, revised version to appear in Phys. Rev.
Is CDM an effective CCDM cosmology?
We show that a cosmology driven by gravitationally induced particle
production of all non-relativistic species existing in the present Universe
mimics exactly the observed flat accelerating CDM cosmology with just
one dynamical free parameter. This kind of scenario includes the creation cold
dark matter (CCDM) model [Lima, Jesus & Oliveira, JCAP 011(2010)027] as a
particular case and also provides a natural reduction of the dark sector since
the vacuum component is not needed to accelerate the Universe. The new cosmic
scenario is equivalent to CDM both at the background and perturbative
levels and the associated creation process is also in agreement with the
universality of the gravitational interaction and equivalence principle.
Implicitly, it also suggests that the present day astronomical observations
cannot be considered the ultimate proof of cosmic vacuum effects in the evolved
Universe because CDM may be only an effective cosmology.Comment: 6 pages, 2 figures, changes in the abstract, introduction, new
references and typo correction
Asteroseismology and Magnetic Cycles
Small cyclic variations in the frequencies of acoustic modes are expected to
be a common phenomenon in solar-like pulsators, as a result of stellar magnetic
activity cycles. The frequency variations observed throughout the solar and
stellar cycles contain information about structural changes that take place
inside the stars as well as about variations in magnetic field structure and
intensity. The task of inferring and disentangling that information is,
however, not a trivial one. In the sun and solar-like pulsators, the direct
effect of the magnetic field on the oscillations might be significantly
important in regions of strong magnetic field (such as solar- / stellar-spots),
where the Lorentz force can be comparable to the gas-pressure gradient. Our aim
is to determine the sun- / stellar-spots effect on the oscillation frequencies
and attempt to understand if this effect contributes strongly to the frequency
changes observed along the magnetic cycle. The total contribution of the spots
to the frequency shifts results from a combination of direct and indirect
effects of the magnetic field on the oscillations. In this first work we
considered only the indirect effect associated with changes in the
stratification within the starspot. Based on the solution of the wave equation
and the variational principle we estimated the impact of these stratification
changes on the oscillation frequencies of global modes in the sun and found
that the induced frequency shifts are about two orders of magnitude smaller
than the frequency shifts observed over the solar cycle.Comment: 4 pages, 6 figures, ESF Conference: The Modern Era of Helio- and
Asteroseismology, to be published on 3 December 2012 at Astronomische
Nachrichten 333, No. 10, 1032-103
Accessing the Acceleration of the Universe with Sunyaev-Zel'dovich and X-ray Data from Galaxy Clusters
By using exclusively the Sunyaev-Zel'dovich effect and X-ray surface
brightness data from 25 galaxy clusters in the redshift range 0.023< z < 0.784
we access cosmic acceleration employing a kinematic description. Such result is
fully independent on the validity of any metric gravity theory, the possible
matter-energy contents filling the Universe, as well as on the SNe Ia Hubble
diagram.Comment: 3 pages, 4 figures, To appear in the Proceedings of the Twelfth
Marcel Grossmann Meeting on General Relativit
Wang-Landau sampling in three-dimensional polymers
Monte Carlo simulations using Wang-Landau sampling are performed to study
three-dimensional chains of homopolymers on a lattice. We confirm the accuracy
of the method by calculating the thermodynamic properties of this system. Our
results are in good agreement with those obtained using Metropolis importance
sampling. This algorithm enables one to accurately simulate the usually hardly
accessible low-temperature regions since it determines the density of states in
a single simulation.Comment: 5 pages, 9 figures arch-ive/Brazilian Journal of Physic
Are Galaxy Clusters Suggesting an Accelerating Universe?
The present cosmic accelerating stage is discussed through a new kinematic
method based on the Sunyaev- Zel'dovich effect (SZE) and X-ray surface
brightness data from galaxy clusters. By using the SZE/X-ray data from 38
galaxy clusters in the redshift range [Bonamente et
al., Astrop. J. {\bf 647}, 25 (2006)] it is found that the present Universe is
accelerating and that the transition from an earlier decelerating to a late
time accelerating regime is relatively recent. The ability of the ongoing
Planck satellite mission to obtain tighter constraints on the expansion history
through SZE/X-ray angular diameters is also discussed. Our results are fully
independent on the validity of any metric gravity theory, the possible matter-
energy contents filling the Universe, as well as on the SNe Ia Hubble diagram
from which the presenting accelerating stage was inferred.Comment: 6 pages, 6 figures, AIP Conf. Proc. Invisible Universe: Proceedings
of the Conferenc
Asteroseismic Theory of Rapidly Oscillating Ap Stars
This paper reviews some of the important advances made over the last decade
concerning theory of roAp stars.Comment: 9 pages, 5 figure
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