A hemoglobin és bomlástermékei gátolják a szérum- és a szöveti ACE-aktivitást

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Obesity-induced cognitive impairment in older adults: a microvascular perspective

Over two-thirds of individuals aged 65 and older are obese or overweight in the United States. Epidemiological data show an association between the degree of adiposity and cognitive dysfunction in the elderly. In this review, the pathophysiological roles of microvascular mechanisms, including impaired endothelial function and neurovascular coupling responses, microvascular rarefaction, and blood-brain barrier disruption in the genesis of cognitive impairment in geriatric obesity are considered. The potential contribution of adipose-derived factors and fundamental cellular and molecular mechanisms of senescence to exacerbated obesity-induced cerebromicrovascular impairment and cognitive decline in aging are discussed

Kardiovaszkuláris kutatások a Kardiológiai Intézetben

Társszerzős előadás, első szerző: Édes IstvánTanulmányi rendszerbe betöltv

Modulation of vascular smooth muscle contraction by trasient receptor potencial melastatin-4 (TRPM4)

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A tranziens receptor potenciál melastatin 4 (TRPM-4) vaszkuláris biológiai szerepe

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