Real-time multiframe blind deconvolution of solar images

The quality of images of the Sun obtained from the ground are severely limited by the perturbing effect of the turbulent Earth's atmosphere. The post-facto correction of the images to compensate for the presence of the atmosphere require the combination of high-order adaptive optics techniques, fast measurements to freeze the turbulent atmosphere and very time consuming blind deconvolution algorithms. Under mild seeing conditions, blind deconvolution algorithms can produce images of astonishing quality. They can be very competitive with those obtained from space, with the huge advantage of the flexibility of the instrumentation thanks to the direct access to the telescope. In this contribution we leverage deep learning techniques to significantly accelerate the blind deconvolution process and produce corrected images at a peak rate of ~100 images per second. We present two different architectures that produce excellent image corrections with noise suppression while maintaining the photometric properties of the images. As a consequence, polarimetric signals can be obtained with standard polarimetric modulation without any significant artifact. With the expected improvements in computer hardware and algorithms, we anticipate that on-site real-time correction of solar images will be possible in the near future.Comment: 16 pages, 12 figures, accepted for publication in A&

Contextual factors and contingent reward leadership: employer adoption of telecommuting

Using a contingency perspective, this paper examines the conditions under which telecommuting is most likely to be adopted with data obtained from a sample of 122 CEOs. We hypothesized that telecommuting fits better in younger organizations, firms with a higher proportion of women and international employees in workforce, and companies that offer variable pay. We found evidence that confirm the prediction that telecommuting, a high proportion of international employees, and the use of variable compensation as an internal control mechanism tend to go hand in hand.

Functional diversity of motoneurons in the oculomotor system

Extraocular muscles contain two types of muscle fibers according to their innervation pattern: singly innervated muscle fibers (SIFs), similar to most skeletal muscle fibers, and multiply innervated muscle fibers (MIFs). Morphological studies have revealed that SIF and MIF motoneurons are segregated anatomically and receive different proportions of certain afferents, suggesting that while SIF motoneurons would participate in the whole repertoire of eye movements, MIF motoneurons would contribute only to slow eye movements and fixations. We have tested that proposal by performing single-unit recordings, in alert behaving cats, of electrophysiologically identified MIF and SIF motoneurons in the abducens nucleus. Our results show that both types of motoneuron discharge in relation to eye position and velocity, displaying a tonic–phasic firing pattern for different types of eye movement (saccades, vestibulo-ocular reflex, vergence) and gaze-holding. However, MIF motoneurons presented an overall reduced firing rate compared with SIF motoneurons, and had significantly lower recruitment threshold and also lower eye position and velocity sensitivities. Accordingly, MIF motoneurons could control mainly gaze in the off-direction, when less force is needed, whereas SIF motoneurons would contribute to increase muscle tension progressively toward the on-direction as more force is required. Anatomically, MIF and SIF motoneurons distributed intermingled within the abducens nucleus, with MIF motoneurons being smaller and having a lesser somatic synaptic coverage. Our data demonstrate the functional participation of both MIF and SIF motoneurons in fixations and slow and phasic eye movements, although their discharge properties indicate a functional segregation.Ministerio de Ciencia, Innovación y Universidades – Fondo Europeo de Desarrollo Regional (BFU2015-64515-P)Junta de Andalucía (BIO-297

Vascular Endothelial Growth Factor (VEGF) Prevents the Downregulation of the Cholinergic Phenotype in Axotomized Motoneurons of the Adult Rat

Vascular endothelial growth factor (VEGF) was initially characterized by its activity on the vascular system. However, there is growing evidence indicating that VEGF also acts as a neuroprotective factor, and that its administration to neurons suffering from trauma or disease is able to rescue them from cell death. We questioned whether VEGF could also maintain damaged neurons in a neurotransmissive mode by evaluating the synthesis of their neurotransmitter, and whether its action would be direct or through its well-known angiogenic activity. Adult rat extraocular motoneurons were chosen as the experimental model. Lesion was performed by monocular enucleation and immediately a gelatine sponge soaked in VEGF was implanted intraorbitally. After 7 days, abducens, trochlear, and oculomotor nuclei were examined by immunohistochemistry against choline acetyltransferase (ChAT), the biosynthetic enzyme of the motoneuronal neurotransmitter acetylcholine. Lesioned motoneurons exhibited a noticeable ChAT downregulation which was prevented by VEGF administration. To explore whether this action was mediated via an increase in blood vessels or in their permeability, we performed immunohistochemistry against laminin, glucose transporter-1 and the plasmatic protein albumin. The quantification of the immunolabeling intensity against these three proteins showed no significant differences between VEGF-treated, axotomized and control animals. Therefore, the present data indicate that VEGF is able to sustain the cholinergic phenotype in damaged motoneurons, which is a first step for adequate neuromuscular neurotransmission, and that this action seems to be mediated directly on neurons since no sign of angiogenic activity was evident. These data reinforces the therapeutical potential of VEGF in motoneuronal diseases.España, MINECO and FEDER BFU2015-64515-PJunta de Andalucía and FEDER : P10-CVI605

Anuario Económico de Córdoba 2020

La reinvención de los negocios, el trabajo en equipo, el apoyo de las distintas administraciones y el respaldo de los ciudadanos serán las claves para que las empresas más cercanas puedan sobrevivir

Preparación y estudio como inhibidores de monoamino oxidasa de 6-benciloxi-, 6-metoxi- y 6-hidroxi-indol-2-carbohidracidas N2-sustituidas

Tesis inédita de la Universidad Complutense de Madrid, Facultad de Ciencias, Sección de Químicas, leída en mayo de 1972.Fac. de Ciencias QuímicasTRUEProQuestpu

Xerophytic Lichens from Gypsiferous Outcrops of Arid Areas of Andalusia as a Source of Anti-Phytopathogenic Depsides

In a survey to evaluate the potential of lichens associated with gypsum areas as sources of new antifungal metabolites, six species of lichens were collected in the gypsum outcrops of the Sorbas Desert (Diploschistes ocellatus and Seirophora lacunosa) and the Tabernas Desert (Cladonia foliacea, Acarospora placodiformis, Squamarina lentigera and Xanthoparmelia pokornyi) in southern Spain. Raw lichen acetone extracts were tested against a panel of seven phytopathogenic fungi, including Botrytis cinerea, Colletotrichum acutatum, Fusarium oxysporum f.sp cubense TR4, Fusarium ploriferaum, Magnaporthe grisea, Verticillium dahliae and Zymoseptoria tritici. Active extracts of Cladonia foliacea, Xanthoparmelia pokornyi and Squamarina lentigera were analyzed by HPLC-MS/MS and Molecular Networking to identify possible metabolites responsible for the antifungal activity. A total of ten depside-like metabolites were identified by MS/MS dereplication and NMR experiments, of which one was a new derivative of fumaroprotocetraric acid. The compounds without previously described biological activity were purified and tested against the panel of fungal phytopathogens. Herein, the antifungal activity against fungal phytopathogens of 40-O-methylpaludosic acid, divaricatic acid and stenosporic acid is reported for the first time. Stenosporic and divaricatic acids displayed a broad antifungal spectrum against seven relevant fungal phytopathogens in a micromolar range, including the extremely resistant fungus F. oxysporum f. sp. cubense Tropical Race 4 (TR4). 40-Omethylpaludosic acid exhibited specific antifungal activity against the wheat pathogen Z. tritici, with an IC50 of 38.87 g/mL (87.1 M) in the absorbance-based assay and 24.88 g/mL (55.52 M) in the fluorescence-based assa

Bloch functions on the unit ball of an infinite dimensional Hilbert space

The Bloch space has been studied on the open unit disk of C and some homogeneous domains of Cn. We define Bloch functions on the open unit ball of a Hilbert space E and prove that the corresponding space B(BE) is invariant under composition with the automorphisms of the ball, leading to a norm that — modulo the constant functions — is automorphism invariant as well. All bounded analytic functions on BE are also Bloch functions

Dual encoding of muscle tension and eye position by abducens motoneurons

Extraocular muscle tension associated with spontaneous eye movements has a pulse-slide-step profile similar to that of motoneuron firing rate. Existing models only relate motoneuron firing to eye position, velocity and acceleration. We measured and quantitatively compared lateral rectus muscle force and eye position with the firing of abducens motoneurons in the cat to determine fundamental encoding correlations. During fixations (step), muscle force increased exponentially with eccentric eye position, consistent with a model of estimate ensemble motor innervation based on neuronal sensitivities and recruitment order. Moreover, firing rate in all motoneurons tested was better related to eye position than to muscle tension during fixations. In contrast, during the postsaccadic slide phase, the time constant of firing rate decay was closely related to that of muscle force decay, suggesting that all motoneurons encode muscle tension as well. Discharge characteristics of abducens motoneurons formed overlapping clusters of phasic and tonic motoneurons, thus, tonic units recruited earlier and had a larger slide signal. We conclude that the slide signal is a discharge characteristic of the motoneuron that controls muscle tension during the postsaccadic phase and that motoneurons are specialized for both tension and position-related properties. The organization of signal content in the pool of abducens motoneurons from the very phasic to the very tonic units is possibly a result of the differential trophic background received from distinct types of muscle fibers