879 research outputs found

    SIMULAÇÃO COMO FERRAMENTA DE TOMADA DE DECISÃO DO PROCESSO DE ATENDIMENTO EM EMPRESA DE VAREJO

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    Realizou-se a análise do processo de atendimento nos caixas de um supermercado, por meio da simulação, comparando os resultados obtidos pela simulação com a Teoria das Filas. As variáveis de entrada foram coletadas no sistema real (tempos dos intervalos entre as chegadas sucessivas de clientes nas filas e os tempos de atendimento dos caixas), sendo ajustadas funções de distribuição de probabilidade por meio do teste de Kolmogorov-Smirnov ao nível de 15% de probabilidade. A simulação, quando comparada à Teoria das Filas, mostrou-se uma ferramenta com maior capacidade de representar a realidade, por considerar a variação aleatória dos dados de entrada com maior exatidão. O melhor cenário avaliado sugere a realização de treinamento dos funcionários dos caixas normais e a realocação de um atendente dos caixas normais do turno da manhã para o caixa rápido no turno da tarde, o que contribuiria para a minimização das filas e tempos de espera dos clientes. Os benefícios deste cenário implicam o aumento de eficiência no funcionamento do processo de atendimento, a maior satisfação dos clientes e o equilíbrio na taxa de utilização dos servidores. Palavras-chave: Supermercado. Caixa de atendimento. Arena. Teoria das Filas

    Toxocara Seropositivity, Atopy and Wheezing in Children Living in Poor Neighbourhoods in Urban Latin American

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    Background Toxocara canis and T. cati are parasites of dogs and cats, respectively, that infect humans and cause human toxocariasis. Infection may cause asthma-like symptoms but is often asymptomatic and is associated with a marked eosinophilia. Previous epidemiological studies indicate that T. canis infection may be associated with the development of atopy and asthma. Objectives To investigate possible associations between Toxocara spp. seropositivity and atopy and childhood wheezing in a population of children living in non-affluent areas of a large Latin American city. Methods The study was conducted in the city of Salvador, Brazil. Data on wheezing symptoms were collected by questionnaire, and atopy was measured by the presence of aeroallergen-specific IgE (sIgE). Skin prick test (SPT), total IgE and peripheral eosinophilia were measured. Toxocara seropositivity was determined by the presence of anti-Toxocara IgG antibodies, and intestinal helminth infections were determined by stool microscopy. Findings Children aged 4 to 11 years were studied, of whom 47% were seropositive for anti-Toxocara IgG; eosinophilia >4% occurred in 74.2% and >10% in 25.4%; 59.6% had elevated levels of total IgE; 36.8% had sIgE≥0.70 kU/L and 30.4% had SPT for at least one aeroallergen; 22.4% had current wheezing symptoms. Anti-Toxocara IgG was positively associated with elevated eosinophils counts, total IgE and the presence of specific IgE to aeroallergens but was inversely associated with skin prick test reactivity. Conclusion The prevalence of Toxocara seropositivity was high in the studied population of children living in conditions of poverty in urban Brazil. Toxocara infection, although associated with total IgE, sIgE and eosinophilia, may prevent the development of skin hypersensitivity to aeroallergens, possibly through increased polyclonal IgE and the induction of a modified Th2 immune reaction
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