Experimental studies on the aerodynamic performance and dynamic response of flow direction sensing vanes

Systematic investigations were performed on a variety of aerodynamic surfaces to obtain their potential for possible application to wind vanes. Among the surfaces tested were: (1) single vanes consisting of flat plates of various planforms having aspect ratios between 0.5 and 5; (2) bi-vanes with aspect ratio 2.5; (3) various cone and box vanes; and (4) various cruciform configurations. The models were subjected to windtunnel tests. In addition to lift and drag force measurements, damping and frequency test were performed under a variety of flow conditions

Estimation of automobile-driver describing function from highway tests using the double steering wheel

The automobile-driver describing function for lateral position control was estimated for three subjects from frequency response analysis of straight road test results. The measurement procedure employed an instrumented full size sedan with known steering response characteristics, and equipped with a lateral lane position measuring device based on video detection of white stripe lane markings. Forcing functions were inserted through a servo driven double steering wheel coupling the driver to the steering system proper. Random appearing, Gaussian, and transient time functions were used. The quasi-linear models fitted to the random appearing input frequency response characterized the driver as compensating for lateral position error in a proportional, derivative, and integral manner. Similar parameters were fitted to the Gabor transformed frequency response of the driver to transient functions. A fourth term corresponding to response to lateral acceleration was determined by matching the time response histories of the model to the experimental results. The time histories show evidence of pulse-like nonlinear behavior during extended response to step transients which appear as high frequency remnant power

Artful Liars: Malingering on the Draw-A-Person Task

Malingering is a form of deception in which one fakes illness to earn (positive or negative) reinforcement. The purpose of the current research was to explore the ability of naïve participants to malinger distress on a clinical, projective measure (Draw-A-Person; DAP). In two experiments, individuals first drew figures of a man, woman, and self. Then, they imagined they were in a motor vehicle accident and drew the figures again as if they were falsely claiming distress from the accident. In Experiment 1, 65 undergraduates participated and in Experiment 2, 70 undergraduates and 40 high school students participated. The drawings were objectively scored using a standardized protocol and ‘honest’ and ‘malingered’ drawings were compared. In both Experiments, participants successfully malingered distress and did so by drawing more “primitively”, earning lower cognitive ability scores on their malingered drawings. Hence, objectively-scored DAP tasks are vulnerable to deliberate distortion by naïve individuals, though malingering detection may be possible in the future via cognitive skill scores. However, reliance on DAP tasks for diagnostic or forensic purposes currently seems questionable

Fast response vanes for sensing flow patterns in helicopter rotor environment

Wind tunnel experiments were conducted on four small-scale flow-direction vanes for the determination of aerodynamic response. The tests were further extended to include a standard sized low-inertia vane currently employed in aircraft flight testing. The four test vanes had different aspect ratios and were about 35 percent of the surface area of the standard vane. The test results indicate satisfactory damping and frequency response for all vanes tested and compare favorably with the standard design

Power requirement of rotating rods in airflow

Experiments were performed to determine the power required for rotating a rotor disc fitted with a number of radially arranged rods placed into a ducted airflow. An array of stationary rods, also radially arranged, were placed upstream close to the rotor with a small gap between the rods to cause wake interference. The results show that power increased with increasing airflow and the rate of increase varied considerably. At lower values of airflow the rate of increase was larger than at higher airflow and definite power peaks occurred at certain airflow rates, where the power attained a maximum within the test airflow range. During the test a maximum blade passage frequency of 2037 Hz was attained

Xrn1/Pacman affects apoptosis and regulates expression of hid and reaper

Programmed cell death, or apoptosis, is a highly conserved cellular process that is crucial for tissue homeostasis under normal development as well as environmental stress. Misregulation of apoptosis is linked to many developmental defects and diseases such as tumour formation, autoimmune diseases and neurological disorders. In this paper, we show a novel role for the exoribonuclease Pacman/Xrn1 in regulating apoptosis. Using Drosophila wing imaginal discs as a model system, we demonstrate that a null mutation in pacman results in small imaginal discs as well as lethality during pupation. Mutant wing discs show an increase in the number of cells undergoing apoptosis, especially in the wing pouch area. Compensatory proliferation also occurs in these mutant discs, but this is insufficient to compensate for the concurrent increase in apoptosis. The phenotypic effects of the pacman null mutation are rescued by a deletion that removes one copy of each of the pro-apoptotic genes reaper, hid and grim, demonstrating that pacman acts through this pathway. The null pacman mutation also results in a significant increase in the expression of the pro-apoptotic mRNAs, hid and reaper, with this increase mostly occurring at the post-transcriptional level, suggesting that Pacman normally targets these mRNAs for degradation. Our results uncover a novel function for the conserved exoribonuclease Pacman and suggest that this exoribonuclease is important in the regulation of apoptosis in other organisms

Changes in Assortative Matching and Inequality in Income: Evidence for the UK

The extent to which like‐with‐like marry is important for inequality as well as for the outcomes of children who result from the union. In this paper, we present evidence on changes in assortative mating and its implications for household inequality in the UK. Our approach contrasts with others in the literature in that it is consistent with an underlying model of the marriage market. We argue that a key advantage of this approach is that it creates a direct connection between changes in assortativeness in marriage and changes in the value of marriage for the various possible matches by education group. Our empirical results do not show a clear direction of change in assortativeness in the UK between the birth cohorts of 1945–54 and 1965–74. We find that changes in assortativeness pushed income inequality up slightly, but that the strong changes in education attainment across the two cohorts contributed to scale down inequality

Microdosimetry of photoneutrons around medical linear accelerators.

Photoneutrons produced in the vicinity of medical linear accelerators for therapy, constitute a hazard which is difficult to assess and monitor. The aims of the project were to develop new techniques, using microdosimetry, which would be suitable for the improved quality control of pulsed photon beams and for the assessment of the associated photoneutron hazard in typical treatment facilities from the perspective of the patients and staff. The measurements of photoneutron yields and equivalent doses were obtained using activation analysis detectors around a 10 MV LINAC. To obtain adequate statistical precision, an optimum thickness of 2.5 cm of polyethylene was used that doubled the detector's sensitivity. This enabled the yields and spatial distribution of the low intensity field to be recorded. Photoneutron equivalent dose-rates of up to 0.104 Sv.h-1, or 0.1% of the useful photon dose- rates, were measured. In the literature, however, it was found that equivalent dose-rates could reach as high as 1 % of the useful photon treatment dose-rate for machines operating at X ray energies of ≥18 MV. Thus it is recommended that to uphold the principle of ALARA, such high energies (≥18 MV) should only be used when no lower energy machine is available. Microdosimetry with a tissue equivalent proportional counter (TEPC) microdosimeter, enabled the photoneutron contribution to the quality spectrum to be identified in the maze to the treatment room of the 10 MV LIN AC, and the photoneutrons there were assigned a radiation weighting factor of 20. The known problems concerning the rf interference and very high pulsed dose-rates inside the treatment room proved too severe to obtain meaningful results with the TEPC. The microdosimeter did however provide useful diagnostic information. Furthermore, a novel calibration technique for TEPC's was developed and an established one, the proton-edge method, was improved. A new approach was adopted to conduct microdosimetry in the vicinity of medical accelerators. This involved the design of a condensed phase microdosimeter comprising, a miniature CsI(T1) scintillator coupled to an optical fibre 20 m long, for conducting in-beam, on-line measurements of quality spectra. However, Cerenkov light and scintillation light produced in the optical fibre by the radiation fields was the cause of strong interference that has yet to be overcome. The application of the microdosimeter, which is still under development, to brachytherapy is proposed for in-vivo measurements

Charged black holes: Wave equations for gravitational and electromagnetic perturbations

A pair of wave equations for the electromagnetic and gravitational perturbations of the charged Kerr black hole are derived. The perturbed Einstein-Maxwell equations in a new gauge are employed in the derivation. The wave equations refer to the perturbed Maxwell spinor $\Phi_0$ and to the shear $\sigma$ of a principal null direction of the Weyl curvature. The whole construction rests on the tripod of three distinct derivatives of the first curvature $\kappa$ of a principal null direction.Comment: 12 pages, to appear in Ap.

T-tubule disease:Relationship between t-tubule organization and regional contractile performance in human dilated cardiomyopathy

Evidence from animal models suggest that t-tubule changes may play an important role in the contractile deficit associated with heart failure. However samples are usually taken at random with no regard as to regional variability present in failing hearts which leads to uncertainty in the relationship between contractile performance and possible t-tubule derangement. Regional contraction in human hearts was measured by tagged cine MRI and model fitting. At transplant, failing hearts were biopsy sampled in identified regions and immunocytochemistry was used to label t-tubules and sarcomeric z-lines. Computer image analysis was used to assess 5 different unbiased measures of t-tubule structure/organization. In regions of failing hearts that showed good contractile performance, t-tubule organization was similar to that seen in normal hearts, with worsening structure correlating with the loss of regional contractile performance. Statistical analysis showed that t-tubule direction was most highly correlated with local contractile performance, followed by the amplitude of the sarcomeric peak in the Fourier transform of the t-tubule image. Other area based measures were less well correlated. We conclude that regional contractile performance in failing human hearts is strongly correlated with the local t-tubule organization. Cluster tree analysis with a functional definition of failing contraction strength allowed a pathological definition of ‘t-tubule disease’. The regional variability in contractile performance and cellular structure is a confounding issue for analysis of samples taken from failing human hearts, although this may be overcome with regional analysis by using tagged cMRI and biopsy mapping